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Lineage-specific pulmonary transcriptome landscape of coronavirus infection unveils universal immunotherapy for viral pneumonia

In the infection courses of different SARS-CoV-2 variants, disease outcomes and signatures were delineated by physiological changes, viral load, pathology, and pulmonary transcriptome analysis. This multi-dimensional landscape of disease outcomes and underlying mechanisms might provide important clues for immunotherapy of SARS-CoV-2 infection and pneumonia caused by other respiratory viruses.

AgentDrift: Unsafe Recommendation Drift Under Tool Corruption Hidden by Ranking Metrics in LLM Agents

arXiv:2603.12564v5 Announce Type: replace-cross Abstract: Tool-augmented LLM agents increasingly operate as multi-turn advisors in high-stakes domains, yet their evaluation relies on ranking metrics that measure what is recommended but not whether it is safe for the user. We present a paired-trajectory protocol that replays real financial dialogues under clean and contaminated tool-output conditions across eight LLMs (7B to frontier), decomposing divergence into information-channel and memory-channel mechanisms. We observe evaluation blindness: recommendation quality is preserved under contamination (UPR~1.0) while risk-inappropriate products appear in 65-93% of turns, invisible to standard NDCG. Violations are information-channel-driven, emerge at turn 1, and persist without self-correction over 23-step trajectories. Even non-extreme perturbations (within-band corruption, narrative-only attacks) evade threshold monitors while producing significant drift. Susceptibility scales with instruction-following fidelity across all eight models. Sparse autoencoder probing reveals models internally distinguish adversarial perturbations but fail to propagate this signal to output; causal interventions (activation patching, feature clamping, direct steering) confirm this representation-to-action gap is structural and resists linear repair. A safety-penalized NDCG variant (sNDCG) reduces preservation ratios to 0.51-0.74. These results motivate trajectory-level safety monitoring for deployed multi-turn agents.

AgentDrift: Unsafe Recommendation Drift Under Tool Corruption Hidden by Ranking Metrics in LLM Agents

arXiv:2603.12564v1 Announce Type: cross Abstract: Tool-augmented LLM agents increasingly serve as multi-turn advisors in high-stakes domains, yet their evaluation relies on ranking-quality metrics that measure what is recommended but not whether it is safe for the user. We introduce a paired-trajectory protocol that replays real financial dialogues under clean and contaminated tool-output conditions across seven LLMs (7B to frontier) and decomposes divergence into information-channel and memory-channel mechanisms. Across the seven models tested, we consistently observe the evaluation-blindness pattern: recommendation quality is largely preserved under contamination (utility preservation ratio approximately 1.0) while risk-inappropriate products appear in 65-93% of turns, a systematic safety failure poorly reflected by standard NDCG. Safety violations are predominantly information-channel-driven, emerge at the first contaminated turn, and persist without self-correction over 23-step trajectories; no agent across 1,563 contaminated turns explicitly questions tool-data reliability. Even narrative-only corruption (biased headlines, no numerical manipulation) induces significant drift while completely evading consistency monitors. A safety-penalized NDCG variant (sNDCG) reduces preservation ratios to 0.51-0.74, indicating that much of the evaluation gap becomes visible once safety is explicitly measured. These results motivate considering trajectory-level safety monitoring, beyond single-turn quality, for deployed multi-turn agents in high-stakes settings.

CognitionCapturerPro: Towards High-Fidelity Visual Decoding from EEG/MEG via Multi-modal Information and Asymmetric Alignment

arXiv:2603.12722v1 Announce Type: cross Abstract: Visual stimuli reconstruction from EEG remains challenging due to fidelity loss and representation shift. We propose CognitionCapturerPro, an enhanced framework that integrates EEG with multi-modal priors (images, text, depth, and edges) via collaborative training. Our core contributions include an uncertainty-weighted similarity scoring mechanism to quantify modality-specific fidelity and a fusion encoder for integrating shared representations. By employing a simplified alignment module and a pre-trained diffusion model, our method significantly outperforms the original CognitionCapturer on the THINGS-EEG dataset, improving Top-1 and Top-5 retrieval accuracy by 25.9% and 10.6%, respectively. Code is available at: https://github.com/XiaoZhangYES/CognitionCapturerPro.
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