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  • ✇cs.AI, q-bio.NC updates on arXiv.org
  • RelayS2S: A Dual-Path Speculative Generation for Real-Time Dialogue Long Mai · Junli Liang
    arXiv:2603.23346v2 Announce Type: replace Abstract: Real-time spoken dialogue systems face a fundamental tension between latency and response quality. End-to-end speech-to-speech (S2S) models respond immediately and naturally handle turn-taking, backchanneling, and interruption, but produce semantically weaker outputs. Cascaded pipelines (ASR -> LLM) deliver stronger responses at the cost of latency that grows with model size. We present RelayS2S, a hybrid architecture that runs two paths in
     

RelayS2S: A Dual-Path Speculative Generation for Real-Time Dialogue

arXiv:2603.23346v2 Announce Type: replace Abstract: Real-time spoken dialogue systems face a fundamental tension between latency and response quality. End-to-end speech-to-speech (S2S) models respond immediately and naturally handle turn-taking, backchanneling, and interruption, but produce semantically weaker outputs. Cascaded pipelines (ASR -> LLM) deliver stronger responses at the cost of latency that grows with model size. We present RelayS2S, a hybrid architecture that runs two paths in parallel upon turn detection. The fast path - a duplex S2S model - speculatively drafts a short response prefix that is streamed immediately to TTS for low-latency response onset, while continuing to monitor live audio events. The slow path - a cascaded ASR -> LLM pipeline - generates a higher-quality continuation conditioned on the committed prefix, producing an uninterrupted utterance. A lightweight learned verifier gates the handoff, committing the prefix when appropriate or falling back gracefully to the cascaded pipeline. With GPT-4.1 as the back-end, RelayS2S substantially reduces response latency while preserving nearly all of the cascaded pipeline's textual quality. On synthetic voice dialogues, it achieves a P90 first-chunk latency of 81 ms, excluding TTS and network latency, compared with 1,006 ms for the cascaded baseline. On real voice dialogues, RelayS2S reduces average first-chunk latency by 479 ms while retaining 99% of the cascaded pipeline's textual quality. These benefits become larger as the slow-path model scales. Because the prefix handoff requires no architectural modification to either component, RelayS2S serves as a lightweight, drop-in addition to existing cascaded pipelines. Our code is publicly available at: https://github.com/mailong25/relays2s

SentGraph: Hierarchical Sentence Graph for Multi-hop Retrieval-Augmented Question Answering

arXiv:2601.03014v3 Announce Type: replace-cross Abstract: Traditional Retrieval-Augmented Generation (RAG) effectively supports single-hop question answering with large language models but faces significant limitations in multi-hop question answering tasks, which require combining evidence from multiple documents. Existing chunk-based retrieval often provides irrelevant and logically incoherent context, leading to incomplete evidence chains and incorrect reasoning during answer generation. To address these challenges, we propose SentGraph, a sentence-level graph-based RAG framework that explicitly models fine-grained logical relationships between sentences for multi-hop question answering. Specifically, we construct a hierarchical sentence graph offline by first adapting Rhetorical Structure Theory to distinguish nucleus and satellite sentences, and then organizing them into topic-level subgraphs with cross-document entity bridges. During online retrieval, SentGraph performs graph-guided evidence selection and path expansion to retrieve fine-grained sentence-level evidence. Extensive experiments on four multi-hop question answering benchmarks demonstrate the effectiveness of SentGraph, validating the importance of explicitly modeling sentence-level logical dependencies for multi-hop reasoning.

A Deployment-Friendly Foundational Framework for Efficient Computational Pathology

arXiv:2602.14010v1 Announce Type: cross Abstract: Pathology foundation models (PFMs) have enabled robust generalization in computational pathology through large-scale datasets and expansive architectures, but their substantial computational cost, particularly for gigapixel whole slide images, limits clinical accessibility and scalability. Here, we present LitePath, a deployment-friendly foundational framework designed to mitigate model over-parameterization and patch level redundancy. LitePath integrates LiteFM, a compact model distilled from three large PFMs (Virchow2, H-Optimus-1 and UNI2) using 190 million patches, and the Adaptive Patch Selector (APS), a lightweight component for task-specific patch selection. The framework reduces model parameters by 28x and lowers FLOPs by 403.5x relative to Virchow2, enabling deployment on low-power edge hardware such as the NVIDIA Jetson Orin Nano Super. On this device, LitePath processes 208 slides per hour, 104.5x faster than Virchow2, and consumes 0.36 kWh per 3,000 slides, 171x lower than Virchow2 on an RTX3090 GPU. We validated accuracy using 37 cohorts across four organs and 26 tasks (26 internal, 9 external, and 2 prospective), comprising 15,672 slides from 9,808 patients disjoint from the pretraining data. LitePath ranks second among 19 evaluated models and outperforms larger models including H-Optimus-1, mSTAR, UNI2 and GPFM, while retaining 99.71% of the AUC of Virchow2 on average. To quantify the balance between accuracy and efficiency, we propose the Deployability Score (D-Score), defined as the weighted geometric mean of normalized AUC and normalized FLOP, where LitePath achieves the highest value, surpassing Virchow2 by 10.64%. These results demonstrate that LitePath enables rapid, cost-effective and energy-efficient pathology image analysis on accessible hardware while maintaining accuracy comparable to state-of-the-art PFMs and reducing the carbon footprint of AI deployment.
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