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IV Co-Scientist: Multi-Agent LLM Framework for Causal Instrumental Variable Discovery

arXiv:2602.07943v2 Announce Type: replace Abstract: In the presence of confounding between an endogenous variable and the outcome, instrumental variables (IVs) are used to isolate the causal effect of the endogenous variable. Identifying valid instruments requires interdisciplinary knowledge, creativity, and contextual understanding, making it a non-trivial task. In this paper, we investigate whether large language models (LLMs) can aid in this task. We perform a two-stage evaluation framework. First, we test whether LLMs can recover well-established instruments from the literature, assessing their ability to replicate standard reasoning. Second, we evaluate whether LLMs can identify and avoid instruments that have been empirically or theoretically discredited. Building on these results, we introduce IV Co-Scientist, a multi-agent system that proposes, critiques, and refines IVs for a given treatment-outcome pair. We also introduce a statistical test to contextualize consistency in the absence of ground truth. Our results show the potential of LLMs to discover valid instrumental variables from a large observational database.

Causality Is Key to Understand and Balance Multiple Goals in Trustworthy ML and Foundation Models

arXiv:2502.21123v5 Announce Type: replace-cross Abstract: Ensuring trustworthiness in machine learning (ML) systems is crucial as they become increasingly embedded in high-stakes domains. This paper advocates for integrating causal methods into machine learning to navigate the trade-offs among key principles of trustworthy ML, including fairness, privacy, robustness, accuracy, and explainability. While these objectives should ideally be satisfied simultaneously, they are often addressed in isolation, leading to conflicts and suboptimal solutions. Drawing on existing applications of causality in ML that successfully align goals such as fairness and accuracy or privacy and robustness, this paper argues that a causal approach is essential for balancing multiple competing objectives in both trustworthy ML and foundation models. Beyond highlighting these trade-offs, we examine how causality can be practically integrated into ML and foundation models, offering solutions to enhance their reliability and interpretability. Finally, we discuss the challenges, limitations, and opportunities in adopting causal frameworks, paving the way for more accountable and ethically sound AI systems.
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