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Lineage-specific pulmonary transcriptome landscape of coronavirus infection unveils universal immunotherapy for viral pneumonia

In the infection courses of different SARS-CoV-2 variants, disease outcomes and signatures were delineated by physiological changes, viral load, pathology, and pulmonary transcriptome analysis. This multi-dimensional landscape of disease outcomes and underlying mechanisms might provide important clues for immunotherapy of SARS-CoV-2 infection and pneumonia caused by other respiratory viruses.

PiXTime: A Model for Federated Time Series Forecasting with Heterogeneous Data across Nodes

arXiv:2601.05613v2 Announce Type: replace-cross Abstract: While collaborative forecasting on distributed time series is highly desirable, directly pooling localized datasets is often impractical due to data sharing constraints. Federated learning offers a promising alternative, yet conventional federated learning algorithms require homogeneous model architectures, which are incompatible with the structural discrepancies, such as unaligned temporal resolutions and mismatched variable channels, commonly observed across decentralized nodes. To bridge this gap, we introduce PiXTime, a novel Transformer-based framework designed to natively accommodate and leverage structurally heterogeneous temporal data. At its core, PiXTime adopts a parameter-decoupling architecture, strategically partitioning the model into localized personalized modules and a globally aggregated shared backbone. Specifically, node-specific local modules act as dimensional adapters, projecting raw sequences of diverse lengths into a unified representation space. Concurrently, a globally synchronized VE Table injects consistent categorical identities into the feature space, allowing the shared backbone to collaboratively learn and generalize representations across inconsistent variable distributions. Comprehensive evaluations on multiple benchmarks demonstrate that PiXTime achieves state-of-the-art performance in heterogeneous federated environments, while maintaining robust superiority in standard homogeneous and centralized forecasting settings.

InCoder-32B: Code Foundation Model for Industrial Scenarios

arXiv:2603.16790v3 Announce Type: replace-cross Abstract: Recent code large language models have achieved remarkable progress on general programming tasks. Nevertheless, their performance degrades significantly in industrial scenarios that require reasoning about hardware semantics, specialized language constructs, and strict resource constraints. To address these challenges, we introduce InCoder-32B (Industrial-Coder-32B), the first 32B-parameter code foundation model unifying code intelligence across chip design, GPU kernel optimization, embedded systems, compiler optimization, and 3D modeling. By adopting an efficient architecture, we train InCoder-32B from scratch with general code pre-training, curated industrial code annealing, mid-training that progressively extends context from 8K to 128K tokens with synthetic industrial reasoning data, and post-training with execution-grounded verification. We conduct extensive evaluation on 14 mainstream general code benchmarks and 9 industrial benchmarks spanning 4 specialized domains. Results show InCoder-32B achieves highly competitive performance on general tasks while establishing strong open-source baselines across industrial domains.

CMMR-VLN: Vision-and-Language Navigation via Continual Multimodal Memory Retrieval

arXiv:2603.07997v1 Announce Type: new Abstract: Although large language models (LLMs) are introduced into vision-and-language navigation (VLN) to improve instruction comprehension and generalization, existing LLM- based VLN lacks the ability to selectively recall and use relevant priori experiences to help navigation tasks, limiting their performance in long-horizon and unfamiliar scenarios. In this work, we propose CMMR-VLN (Continual Multimodal Memory Retrieval based VLN), a VLN framework that endows LLM agents with structured memory and reflection capabilities. Specifically, the CMMR-VLN constructs a multimodal experi- ence memory indexed by panoramic visual images and salient landmarks to retrieve relevant experiences during navigation, introduces a retrieved-augmented generation pipeline to mimick how experienced human navigators leverage priori knowledge, and incorporates a reflection-based memory update strategy that selectively stores complete successful paths and the key initial mistake in failure cases. Comprehensive tests illustrate average success rate improvements of 52.9%, 20.9% and 20.9%, and 200%, 50% and 50% over the NavGPT, the MapGPT, and the DiscussNav in simulation and real tests, respectively eluci- dating the great potential of the CMMR-VLN as a backbone VLN framework.

ViSA-Enhanced Aerial VLN: A Visual-Spatial Reasoning Enhanced Framework for Aerial Vision-Language Navigation

arXiv:2603.08007v1 Announce Type: cross Abstract: Existing aerial Vision-Language Navigation (VLN) methods predominantly adopt a detection-and-planning pipeline, which converts open-vocabulary detections into discrete textual scene graphs. These approaches are plagued by inadequate spatial reasoning capabilities and inherent linguistic ambiguities. To address these bottlenecks, we propose a Visual-Spatial Reasoning (ViSA) enhanced framework for aerial VLN. Specifically, a triple-phase collaborative architecture is designed to leverage structured visual prompting, enabling Vision-Language Models (VLMs) to perform direct reasoning on image planes without the need for additional training or complex intermediate representations. Comprehensive evaluations on the CityNav benchmark demonstrate that the ViSA-enhanced VLN achieves a 70.3\% improvement in success rate compared to the fully trained state-of-the-art (SOTA) method, elucidating its great potential as a backbone for aerial VLN systems.
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