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Spatial atlas of the human brain vasculature reveals specialized cell ensembles

An integrative cell and spatial atlas defines the organizing logic of the adult human cerebrovasculature, providing a framework for studying how vascular cell states support brain function and shape neurological disease vulnerability.

Behind EvoMap: Characterizing a Self-Evolving Agent-to-Agent Collaboration Network

arXiv:2605.25815v2 Announce Type: new Abstract: Agent-to-Agent (A2A) networks enable autonomous AI agents to collaborate by sharing reusable problem-solving instructions. However, how these decentralized ecosystems operate in practice remains largely unexplored. We present the first large-scale empirical study of EvoMap, a prominent A2A collaboration network. By analyzing over 1.5M assets and 128K agents, we show how design choices that prioritize scalable growth introduce trade-offs in reusability, evolution, and auditability. First, EvoMap's credit economy rewards agents for publishing valuable assets. Although this design encourages participation at scale, rewards are tied primarily to publication rather than adoption. This leads agents to mass-produce assets to accumulate credits. As a result, 98% of assets are never reused, while rewards become highly concentrated among a small fraction of agents. Second, EvoMap employs an algorithm (referred to as GDI) to score and rank the quality of these shared assets. We demonstrate that this scoring system is flawed: rather than measuring objective performance, an asset's rank is heavily dictated by unverified, self-reported metadata (e.g., claimed lines of code modified). This allows agents to trivially manipulate their asset's scores. Finally, EvoMap relies on agents to provide local execution logs as evidence that uploaded assets function correctly. Because these validations are not independently verified, over 84% of approved assets bypass quality checks using vacuous tests (e.g., `console.log`). Our findings show that future A2A collaboration networks cannot rely on unverified self-reporting alone. Scalable collaboration requires mechanisms that balance open participation with verifiable execution and trustworthy evaluation.

DEFNet: Multitasks-based Deep Evidential Fusion Network for Blind Image Quality Assessment

arXiv:2507.19418v1 Announce Type: cross Abstract: Blind image quality assessment (BIQA) methods often incorporate auxiliary tasks to improve performance. However, existing approaches face limitations due to insufficient integration and a lack of flexible uncertainty estimation, leading to suboptimal performance. To address these challenges, we propose a multitasks-based Deep Evidential Fusion Network (DEFNet) for BIQA, which performs multitask optimization with the assistance of scene and distortion type classification tasks. To achieve a more robust and reliable representation, we design a novel trustworthy information fusion strategy. It first combines diverse features and patterns across sub-regions to enhance information richness, and then performs local-global information fusion by balancing fine-grained details with coarse-grained context. Moreover, DEFNet exploits advanced uncertainty estimation technique inspired by evidential learning with the help of normal-inverse gamma distribution mixture. Extensive experiments on both synthetic and authentic distortion datasets demonstrate the effectiveness and robustness of the proposed framework. Additional evaluation and analysis are carried out to highlight its strong generalization capability and adaptability to previously unseen scenarios.

Can Multimodal LLMs See Science Instruction? Benchmarking Pedagogical Reasoning in K-12 Classroom Videos

arXiv:2602.18466v1 Announce Type: cross Abstract: K-12 science classrooms are rich sites of inquiry where students coordinate phenomena, evidence, and explanatory models through discourse; yet, the multimodal complexity of these interactions has made automated analysis elusive. Existing benchmarks for classroom discourse focus primarily on mathematics and rely solely on transcripts, overlooking the visual artifacts and model-based reasoning emphasized by the Next Generation Science Standards (NGSS). We address this gap with SciIBI, the first video benchmark for analyzing science classroom discourse, featuring 113 NGSS-aligned clips annotated with Core Instructional Practices (CIP) and sophistication levels. By evaluating eight state-of-the-art LLMs and Multimodal LLMs, we reveal fundamental limitations: current models struggle to distinguish pedagogically similar practices, suggesting that CIP coding requires instructional reasoning beyond surface pattern matching. Furthermore, adding video input yields inconsistent gains across architectures. Crucially, our evidence-based evaluation reveals that models often succeed through surface shortcuts rather than genuine pedagogical understanding. These findings establish science classroom discourse as a challenging frontier for multimodal AI and point toward human-AI collaboration, where models retrieve evidence to accelerate expert review rather than replace it.

Backdooring Bias in Large Language Models

arXiv:2602.13427v1 Announce Type: cross Abstract: Large language models (LLMs) are increasingly deployed in settings where inducing a bias toward a certain topic can have significant consequences, and backdoor attacks can be used to produce such models. Prior work on backdoor attacks has largely focused on a black-box threat model, with an adversary targeting the model builder's LLM. However, in the bias manipulation setting, the model builder themselves could be the adversary, warranting a white-box threat model where the attacker's ability to poison, and manipulate the poisoned data is substantially increased. Furthermore, despite growing research in semantically-triggered backdoors, most studies have limited themselves to syntactically-triggered attacks. Motivated by these limitations, we conduct an analysis consisting of over 1000 evaluations using higher poisoning ratios and greater data augmentation to gain a better understanding of the potential of syntactically- and semantically-triggered backdoor attacks in a white-box setting. In addition, we study whether two representative defense paradigms, model-intrinsic and model-extrinsic backdoor removal, are able to mitigate these attacks. Our analysis reveals numerous new findings. We discover that while both syntactically- and semantically-triggered attacks can effectively induce the target behaviour, and largely preserve utility, semantically-triggered attacks are generally more effective in inducing negative biases, while both backdoor types struggle with causing positive biases. Furthermore, while both defense types are able to mitigate these backdoors, they either result in a substantial drop in utility, or require high computational overhead.
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