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The Effectiveness of Digital Intervention on Psychological Resilience in Postoperative Breast Cancer Patients During Chemotherapy Intervals: Quasi-Experimental Study

Background: Patients with breast cancer during postoperative chemotherapy intervals commonly experience psychological distress and reduced resilience while recovering at home. Digital mindfulness interventions may provide accessible psychological support during this vulnerable period; however, evidence regarding tailored interventions for postoperative patients with breast cancer during chemotherapy intervals remains limited. Objective: This study aimed to examine the effectiveness of a digital intervention on psychological resilience in postoperative patients with breast cancer during chemotherapy intervals. Methods: A quasi-experimental study with repeated measures was conducted from October 2021 to June 2022. A total of 80 eligible participants were recruited from the Department of Breast Surgery at a tertiary hospital in Zhejiang Province, China, and 71 completed the study. The control group received routine discharge instructions and nursing follow-ups, whereas the intervention group additionally received an 8-week digital psychological resilience intervention. Outcomes were assessed at baseline (T0), 3 months post intervention (T1), and 6 months post intervention (T2). The measures included the Connor-Davidson Resilience Scale (CD-RISC), Hospital Anxiety and Depression Scale (HADS), Social Support Rating Scale (SSRS), Breast Cancer Survivor Self-Efficacy Scale (BCSSS), and Functional Assessment of Cancer Therapy-Breast (FACT-B). Independent-samples tests, chi-square tests, and repeated-measures ANOVA were performed using SPSS (version 26.0; IBM Corp). Results: No statistically significant baseline differences were observed between the two groups in the outcome measures. At T1, the intervention group had higher CD-RISC scores than the control group (mean 67.58, SD 11.41 vs mean 62.09, SD 10.18; =.036) and higher BCSSS scores (mean 42.36, SD 3.59 vs mean 39.23, SD 4.90; =.003). However, these between-group differences were no longer statistically significant at T2 (>.05). Significant time effects and group×time interaction effects were observed for both psychological resilience and self-efficacy (.05), although both scales showed significant time effects (

Denisovans from southwestern China and their subsistence strategies

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10997-4

Evidence from Bianfu Cave shows specialized hunting, expedient stone-tool production and extensive bone use of Denisovans, providing new insights into their ecology, behaviour and cultural legacy in eastern Asia.

Mode-as-Sequence: Translating Multimodal Motion Prediction into Unified Sequential Mode Modeling

arXiv:2605.24037v1 Announce Type: cross Abstract: Multimodal motion forecasting is inherently under-supervised: each training scene provides only one realized future, yet multiple plausible futures exist. This sparse supervision often leads to mode collapse (redundant hypotheses and insufficient mode coverage) and unreliable confidence ranking when predicting a small set of trajectories. We propose Mode-as-Sequence, a unified decoding framework that translates an unordered mode set into an ordered mode sequence and explicitly models mode-to-mode dependency. Under this framework, we develop two complementary instantiations. ModeSeq performs recurrent mode decoding, where each mode is generated conditioned on the previously generated modes, encouraging diverse, non-redundant hypotheses with calibrated confidence ordering. To remove the mode-by-mode autoregressive bottleneck, we further propose Parallel ModeSeq, which preserves the same causal dependency using masked mode-to-mode self-attention while decoding all modes in a single forward pass, enabling efficient large-$K$ inference and scalable joint-scene prediction. To learn representative modes and calibrated confidence under sparse labels, we introduce Early-Match-Take-All (EMTA) and its joint-scene extension MA-EMTA, together with a lightweight ranking regularizer that reduces confidence inversions. Extensive experiments on large-scale benchmarks demonstrate consistent improvements in both ranking-oriented metrics and best-of-K accuracy across datasets, horizons, and object types. In the Waymo Open Dataset challenges, ModeSeq achieves 1st place in the 2024 LiDAR-free motion prediction track, and Parallel ModeSeq achieves 1st place in the 2025 Interaction Prediction Challenge, validating the effectiveness of Mode-as-Sequence for both accuracy and efficiency.

Rethinking Weak Supervision in Anomaly Detection: A Comprehensive Benchmark

arXiv:2605.26068v2 Announce Type: cross Abstract: Weakly supervised anomaly detection (WSAD) has developed in three primary directions: incomplete, inexact, and inaccurate supervision. However, these directions remain isolated, lacking a unified framework to assess whether they address unique challenges or share fundamental mechanics. This paper introduces WSADBench, the first benchmark that unifies evaluation across distinct weakly supervised scenarios, benchmarking diverse approaches from specialized WSAD methods to advanced tabular foundation models. WSADBench establishes standardized protocols to evaluate 36 algorithms across 4 modalities by systematically varying label quantity, granularity, and quality, revealing the performance boundaries of various methods. Based on over 700K experiments, WSADBench reveals four critical insights: (i) Strong intrinsic correlations exist between these weak supervision scenarios, challenging the isolation of current research directions. (ii) Specialized WSAD algorithms excel only in extreme label-scarcity regimes but are quickly dominated by tabular foundation models and general classification methods as supervision increases or in OOD scenarios. (iii) Unlabeled data shows inconsistent utility across settings, with marginal gains compared to label refinement. (iv) Models exhibit asymmetric sensitivity to different types of label noise. We release WSADBench as an open-source benchmark with code and datasets to facilitate future WSAD research: https://github.com/SUFE-AILAB/WSADBench.

Safety in Embodied AI: A Survey of Risks, Attacks, and Defenses

arXiv:2605.02900v2 Announce Type: replace-cross Abstract: Embodied Artificial Intelligence (Embodied AI) integrates perception, cognition, planning, and interaction into agents that operate in open-world, safety-critical environments. As these systems gain autonomy and enter domains such as transportation, healthcare, and industrial or assistive robotics, ensuring their safety becomes both technically challenging and socially indispensable. Unlike digital AI systems, embodied agents must act under uncertain sensing, incomplete knowledge, and dynamic human-robot interactions, where failures can directly lead to physical harm. This survey provides a comprehensive and structured review of safety research in embodied AI, examining attacks and defenses across the full embodied pipeline, from perception and cognition to planning, action and interaction, and agentic system. We introduce a multi-level taxonomy that unifies fragmented lines of work and connects embodied-specific safety findings with broader advances in vision, language, and multimodal foundation models. Our review synthesizes insights from over 500 papers spanning adversarial, backdoor, jailbreak, and hardware-level attacks; attack detection, safe training and robust inference; and risk-aware human-agent interaction. This analysis reveals several overlooked challenges, including the fragility of multimodal perception fusion, the instability of planning under jailbreak attacks, and the trustworthiness of human-agent interaction in open-ended scenarios. By organizing the field into a coherent framework and identifying critical research gaps, this survey provides a roadmap for building embodied agents that are not only capable and autonomous but also safe, robust, and reliable in real-world deployment.

A pathogen lncRNA secreted into rice sequesters a host miRNA for virulence

Nature, Published online: 20 May 2026; doi:10.1038/s41586-026-10572-x

A fungal long non-coding RNA from Magnaporthe oryzae translocates into rice cells to sequester a host microRNA that normally represses PKR1, a negative immunity regulator, thereby facilitating infection and revealing a widespread RNA-based pathogen–host interaction mechanism.
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  • Grokking as Dimensional Phase Transition in Neural Networks Ping Wang
    arXiv:2604.04655v1 Announce Type: cross Abstract: Neural network grokking -- the abrupt memorization-to-generalization transition -- challenges our understanding of learning dynamics. Through finite-size scaling of gradient avalanche dynamics across eight model scales, we find that grokking is a \textit{dimensional phase transition}: effective dimensionality~$D$ crosses from sub-diffusive (subcritical, $D 1$) at generalization onset, exhibiting self-organized criticality (SOC). Crucially, $D$
     

Grokking as Dimensional Phase Transition in Neural Networks

arXiv:2604.04655v1 Announce Type: cross Abstract: Neural network grokking -- the abrupt memorization-to-generalization transition -- challenges our understanding of learning dynamics. Through finite-size scaling of gradient avalanche dynamics across eight model scales, we find that grokking is a \textit{dimensional phase transition}: effective dimensionality~$D$ crosses from sub-diffusive (subcritical, $D 1$) at generalization onset, exhibiting self-organized criticality (SOC). Crucially, $D$ reflects \textbf{gradient field geometry}, not network architecture: synthetic i.i.d.\ Gaussian gradients maintain $D \approx 1$ regardless of graph topology, while real training exhibits dimensional excess from backpropagation correlations. The grokking-localized $D(t)$ crossing -- robust across topologies -- offers new insight into the trainability of overparameterized networks.

Overcoming missing data in spatial metabolomics with machine learning imputation to accelerate downstream discovery

iScience. 2026 Mar 3;29(4):115203. doi: 10.1016/j.isci.2026.115203. eCollection 2026 Apr 17.

ABSTRACT

Mass spectrometry imaging (MSI)-based spatial metabolomics exhibits extensive missing values; yet, practical guidance on how imputation choices affect both imputation accuracy and downstream spatial analyses remains limited. In this study, we evaluated eight imputation methods, including both existing approaches and a graph convolutional network (GCN)-based method specifically designed for spatial metabolomics data, to identify suitable approaches for spatial metabolomics. To enable comprehensive assessment, we developed an evaluation framework focusing on two objective criteria: (a) imputation accuracy and (b) preservation of spatial cluster structure. We assembled six benchmark datasets spanning mouse brain and liver, human kidney and stomach, and plant seed sections, and conducted controlled dropout simulations of missing values. Across both evaluation dimensions, including imputation accuracy and preservation of spatial cluster structure, RF ranked first overall, and GCN ranked second in both dimensions. Overall, this systematic, dual-perspective benchmark study provides guidance for selecting imputation strategies in spatial metabolomics research.

PMID:41869568 | PMC:PMC12999350 | DOI:10.1016/j.isci.2026.115203

Hierarchical Dual-Change Collaborative Learning for UAV Scene Change Captioning

arXiv:2603.12832v1 Announce Type: cross Abstract: This paper proposes a novel task for UAV scene understanding - UAV Scene Change Captioning (UAV-SCC) - which aims to generate natural language descriptions of semantic changes in dynamic aerial imagery captured from a movable viewpoint. Unlike traditional change captioning that mainly describes differences between image pairs captured from a fixed camera viewpoint over time, UAV scene change captioning focuses on image-pair differences resulting from both temporal and spatial scene variations dynamically captured by a moving camera. The key challenge lies in understanding viewpoint-induced scene changes from UAV image pairs that share only partially overlapping scene content due to viewpoint shifts caused by camera rotation, while effectively exploiting the relative orientation between the two images. To this end, we propose a Hierarchical Dual-Change Collaborative Learning (HDC-CL) method for UAV scene change captioning. In particular, a novel transformer, \emph{i.e.} Dynamic Adaptive Layout Transformer (DALT) is designed to adaptively model diverse spatial layouts of the image pair, where the interrelated features derived from the overlapping and non-overlapping regions are learned within the flexible and unified encoding layer. Furthermore, we propose a Hierarchical Cross-modal Orientation Consistency Calibration (HCM-OCC) method to enhance the model's sensitivity to viewpoint shift directions, enabling more accurate change captioning. To facilitate in-depth research on this task, we construct a new benchmark dataset, named UAV-SCC dataset, for UAV scene change captioning. Extensive experiments demonstrate that the proposed method achieves state-of-the-art performance on this task. The dataset and code will be publicly released upon acceptance of this paper.
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