arXiv:2609.09263v1 Announce Type: cross Abstract: Speech-to-speech (S2S) models now run inside dubbing, translation, and voice agents. Unlike text models, they hear the speaker's voice, which carries the speaker's gender. A faithful system should treat a speaker as who they sound like, not as whoever usually says what they said. Testing this is harder than it looks, since most S2S models answer in a single, fixed output voice, hard-coded so it cannot drift toward a stereotype. Checking the output voice comes back clean even when the model is biased. We therefore ask two questions. When a model re-speaks the input, does the stereotype in the words shift the perceived gender of the output voice (voice rendering)? And when the model states the speaker's gender, does it follow the voice or the content (gender attribution)? We answer both with one controlled experiment crossing male and female voices with masculine-, neutral-, and feminine-stereotyped passages, on five open- and closed-source models in English, Spanish, and Mandarin. The rendered voice shows no stereotype drift. But every model decides the speaker's gender from the content, not the voice. Making the content one step more feminine (masculine -> neutral -> feminine) multiplies the odds of a "female" judgment by 1.7-24. When the content clashes with the voice, the worst model misgenders the speaker in 90% of cases. When they agree, it misgenders in only 2%. The bias thus hides in gender attribution, where fixed-voice evaluation cannot see, and where audits must look as S2S systems increasingly speak for real people.

Within the skin, glutamatergic neurons expressing neurofilament heavy chain (Nefh) play a role in aging. Loss of Nefh during aging drives skin fibroblast senescence and collagen loss, whereas glutamate supplementation improves skin aging phenotypes.

arXiv:2605.16953v2 Announce Type: replace Abstract: While AI-generated hallucinations pose considerable risks, the underlying cognitive mechanisms by which humans can successfully recognize or be misled by these hallucinations remain unclear. To address this problem, this paper explores humans' neural dynamics to characterize how the brain processes hallucinated content. We record EEG signals from 27 participants while they are performing a verification task to judge the correctness of image descriptions generated by a multi-modal large language model (MLLM). Based on an averaged event-related potential (ERP) study, we reveal that multiple cognitive processes, e.g., semantic integration, inferential processing, memory retrieval, and cognitive load, exhibit distinct patterns when humans process hallucinated versus non-hallucinated content. Notably, neural responses to hallucinations that were misjudged versus correctly judged by human participants showed significant differences. This indicates that misjudged AI-generated hallucinations failed to trigger the standard neurocognitive fact verification pathway.

Background: Evidence-based physician-pharmacist collaborative clinics have demonstrated significant short-term benefits for patients with type 2 diabetes (T2D), but their long-term effectiveness remains unclear, especially in primary health care settings. Objective: This study aimed to explore the long-term effectiveness and cost-effectiveness of a novel, digital-driven, multifaceted physician-pharmacist collaborative model for managing patients with T2D in underresourced settings. Methods: We conducted a 12-month cluster randomized controlled trial from May 2021 to December 2022 across 6 primary health care settings in China. Guided by the theory of planned behavior, the intervention involved routine therapy from physicians along with pharmaceutical interventions from pharmacists. These were delivered through a combination of face-to-face visits and mobile health care. The intervention group received 4 face-to-face visits and biweekly remote education sessions over the 12 months. We conducted intention-to-treat analyses to estimate differences in clinical and behavior indicators between the intervention and control groups. Primary outcomes included glycosylated hemoglobin and 10-year atherosclerotic cardiovascular risk. Data were analyzed using adjusted generalized estimation equations. Results: This study included 574 patients (291 in the intervention group and 283 in the control group). Over 12 months, patients in the intervention group had significant reductions in hemoglobin A_1c (–2.57 vs –1.96, respectively; P<.001; 95% CI –1.027 to –0.238) and 10-year atherosclerotic cardiovascular risk (–1.35 vs 0.01, respectively; P<.001; 95% CI –1.690 to –0.630) compared with the control group. Substantial improvements were also observed in several secondary outcomes, including fasting blood glucose, 2-hour postprandial blood glucose, waist circumference, waist-to-hip ratio, blood pressure, triglyceride, and total cholesterol. Total diabetes-related costs decreased, and patient satisfaction improved significantly in the intervention group. There were no significant differences in BMI, high-density lipoprotein, or low-density lipoprotein. Conclusions: These findings suggest that the physician-pharmacist collaborative model could improve the long-term quality and efficiency of T2D management and reduce medical costs in underresourced areas globally. Patients with T2D, especially those with central obesity or high cardiovascular risk, may benefit more from collaborative clinics. Trial Registration: Chinese Clinical Trial Registry ChiCTR2000031839; https://www.chictr.org.cn/showproj.html?proj=51910

arXiv:2603.08090v1 Announce Type: cross Abstract: Significant progress has been achieved in subject-driven text-to-image (T2I) generation, which aims to synthesize new images depicting target subjects according to user instructions. However, evaluating these models remains a significant challenge. Existing benchmarks exhibit critical limitations: 1) insufficient diversity and comprehensiveness in subject images, 2) inadequate granularity in assessing model performance across different subject difficulty levels and prompt scenarios, and 3) a profound lack of actionable insights and diagnostic guidance for subsequent model refinement. To address these limitations, we propose DSH-Bench, a comprehensive benchmark that enables systematic multi-perspective analysis of subject-driven T2I models through four principal innovations: 1) a hierarchical taxonomy sampling mechanism ensuring comprehensive subject representation across 58 fine-grained categories, 2) an innovative classification scheme categorizing both subject difficulty level and prompt scenario for granular capability assessment, 3) a novel Subject Identity Consistency Score (SICS) metric demonstrating a 9.4\% higher correlation with human evaluation compared to existing measures in quantifying subject preservation, and 4) a comprehensive set of diagnostic insights derived from the benchmark, offering critical guidance for optimizing future model training paradigms and data construction strategies. Through an extensive empirical evaluation of 19 leading models, DSH-Bench uncovers previously obscured limitations in current approaches, establishing concrete directions for future research and development.

arXiv:2603.08148v1 Announce Type: cross Abstract: Recently, large language models (LLMs) have gained much attention for the emergence of human-comparable capabilities and huge potential. However, for open-domain implicit question-answering problems, LLMs may not be the ultimate solution due to the reasons of: 1) uncovered or out-of-date domain knowledge, 2) one-shot generation and hence restricted comprehensiveness. To this end, this work proposes a gradual knowledge excavation framework for open-domain complex question answering, where LLMs iteratively and actively acquire external information, and then reason based on acquired historical knowledge. Specifically, during each step of the solving process, the model selects an action to execute, such as querying external knowledge or performing a single logical reasoning step, to gradually progress toward a final answer. Our method can effectively leverage plug-and-play external knowledge and dynamically adjust the strategy for solving complex questions. Evaluated on the StrategyQA dataset, our method achieves 78.17% accuracy with less than 6% parameters of its competitors, setting new SOTA for ~10B-scale LLMs.

arXiv:2602.14257v1 Announce Type: cross Abstract: While Large Language Model (LLM) agents have achieved remarkable progress in complex reasoning tasks, evaluating their performance in real-world environments has become a critical problem. Current benchmarks, however, are largely restricted to idealized simulations, failing to address the practical demands of specialized domains like advertising and marketing analytics. In these fields, tasks are inherently more complex, often requiring multi-round interaction with professional marketing tools. To address this gap, we propose AD-Bench, a benchmark designed based on real-world business requirements of advertising and marketing platforms. AD-Bench is constructed from real user marketing analysis requests, with domain experts providing verifiable reference answers and corresponding reference tool-call trajectories. The benchmark categorizes requests into three difficulty levels (L1-L3) to evaluate agents' capabilities under multi-round, multi-tool collaboration. Experiments show that on AD-Bench, Gemini-3-Pro achieves Pass@1 = 68.0% and Pass@3 = 83.0%, but performance drops significantly on L3 to Pass@1 = 49.4% and Pass@3 = 62.1%, with a trajectory coverage of 70.1%, indicating that even state-of-the-art models still exhibit substantial capability gaps in complex advertising and marketing analysis scenarios. AD-Bench provides a realistic benchmark for evaluating and improving advertising marketing agents, the leaderboard and code can be found at https://github.com/Emanual20/adbench-leaderboard.