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Multi-Agent Memory from a Computer Architecture Perspective: Visions and Challenges Ahead

arXiv:2603.10062v2 Announce Type: replace-cross Abstract: As LLM agents evolve into collaborative multi-agent systems, their memory requirements grow rapidly in complexity. This position paper frames multi-agent memory as a computer architecture problem. We distinguish shared and distributed memory paradigms, propose a three-layer memory hierarchy (I/O, cache, and memory), and identify two critical protocol gaps: cache sharing across agents and structured memory access control. We argue that the most pressing open challenge is multi-agent memory consistency. Our architectural framing provides a foundation for building reliable, scalable multi-agent systems.

Learning Patient-Specific Disease Dynamics with Latent Flow Matching for Longitudinal Imaging Generation

By: Hao Chen Β· Rui Yin Β· Yifan Chen Β· Qi Chen Β· Chao Li
17 February 2026 at 13:00
arXiv:2512.09185v3 Announce Type: replace-cross Abstract: Understanding disease progression is a central clinical challenge with direct implications for early diagnosis and personalized treatment. While recent generative approaches have attempted to model progression, key mismatches remain: disease dynamics are inherently continuous and monotonic, yet latent representations are often scattered, lacking semantic structure, and diffusion-based models disrupt continuity with random denoising process. In this work, we propose to treat the disease dynamic as a velocity field and leverage Flow Matching (FM) to align the temporal evolution of patient data. Unlike prior methods, it captures the intrinsic dynamic of disease, making the progression more interpretable. However, a key challenge remains: in latent space, Auto-Encoders (AEs) do not guarantee alignment across patients or correlation with clinical-severity indicators (e.g., age and disease conditions). To address this, we propose to learn patient-specific latent alignment, which enforces patient trajectories to lie along a specific axis, with magnitude increasing monotonically with disease severity. This leads to a consistent and semantically meaningful latent space. Together, we present $\Delta$-LFM, a framework for modeling patient-specific latent progression with flow matching. Across three longitudinal MRI benchmarks, $\Delta$-LFM demonstrates strong empirical performance and, more importantly, offers a new framework for interpreting and visualizing disease dynamics.
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