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cs.AI, q-bio.NC updates on arXiv.org
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DisDop: Distillation with Domain Priors for Open-Vocabulary Aerial Object Detection
arXiv:2605.24639v1 Announce Type: cross Abstract: With the widespread application of drones in recent years, object detection of aerial images has attracted increasing attention, especially open-vocabulary aerial detection which is not restricted to predefined categories. Due to the scarcity of drone's viewpoint images and their significant differences from natural images, it is difficult to achieve satisfying results by directly applying vanilla open-vocabulary detection methods designed for n
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cs.AI, q-bio.NC updates on arXiv.org
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Safety in Embodied AI: A Survey of Risks, Attacks, and Defenses
arXiv:2605.02900v2 Announce Type: replace-cross Abstract: Embodied Artificial Intelligence (Embodied AI) integrates perception, cognition, planning, and interaction into agents that operate in open-world, safety-critical environments. As these systems gain autonomy and enter domains such as transportation, healthcare, and industrial or assistive robotics, ensuring their safety becomes both technically challenging and socially indispensable. Unlike digital AI systems, embodied agents must act un
Safety in Embodied AI: A Survey of Risks, Attacks, and Defenses
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Omics In Lung
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Dunhuang Daxiefei Decoction ameliorates acute lung injury via the HIF-1alpha/glycolysis/H3K18la axis
J Ethnopharmacol. 2026 Mar 26;365:121591. doi: 10.1016/j.jep.2026.121591. Online ahead of print.ABSTRACTETHNOPHARMACOLOGICAL RELEVANCE: Acute lung injury (ALI) lacks effective therapies. HIF-1α-driven glycolysis can promote histone lactylation and sustain pro-inflammatory (M1) macrophage responses. Daxiefei Decoction (DXFD), a classic traditional Chinese medicine formula, is used for pulmonary inflammatory diseases, but its immunometabolic mechanism remains unclear.AIM OF THE STUDY: To evaluate
Dunhuang Daxiefei Decoction ameliorates acute lung injury via the HIF-1alpha/glycolysis/H3K18la axis
J Ethnopharmacol. 2026 Mar 26;365:121591. doi: 10.1016/j.jep.2026.121591. Online ahead of print.
ABSTRACT
ETHNOPHARMACOLOGICAL RELEVANCE: Acute lung injury (ALI) lacks effective therapies. HIF-1α-driven glycolysis can promote histone lactylation and sustain pro-inflammatory (M1) macrophage responses. Daxiefei Decoction (DXFD), a classic traditional Chinese medicine formula, is used for pulmonary inflammatory diseases, but its immunometabolic mechanism remains unclear.
AIM OF THE STUDY: To evaluate the protective efficacy of DXFD against lipopolysaccharide (LPS)-induced ALI and to determine whether it acts through the HIF-1α/glycolysis/histone H3K18 lactylation (H3K18la) axis to regulate macrophage polarization.
MATERIALS & METHODS: DXFD constituents were characterized by UPLC-LTQ-Orbitrap-MS/MS, followed by network pharmacology, molecular docking, and molecular dynamics (MD) simulations. Lung transcriptomics and metabolomics were performed in ALI mice. Efficacy and mechanisms were assessed in LPS-challenged mice and RAW264.7 macrophages using histopathology, ELISA, qRT-PCR, Western blotting, and immunofluorescence. HIF-1α overexpression was used for validation.
RESULTS: DXFD dose-dependently alleviated lung injury and reduced pro-inflammatory cytokines in vivo, and suppressed M1 polarization in vivo and in LPS-stimulated macrophages. Multi-omics indicated activation of HIF-1α-associated inflammatory and glycolytic programs in ALI, which were normalized by DXFD. DXFD decreased glycolytic enzyme expression and reduced histone H3K18 lactylation (H3K18la); these effects were partially reversed by HIF-1α overexpression. Molecular docking and dynamics suggested stable binding of baicalin to HIF-1α.
CONCLUSIONS: DXFD mitigates ALI by dampening HIF-1α-dependent glycolysis and H3K18la, thereby restraining M1-driven inflammatory amplification.
PMID:41903585 | DOI:10.1016/j.jep.2026.121591
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cs.AI, q-bio.NC updates on arXiv.org
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JFTA-Bench: Evaluate LLM's Ability of Tracking and Analyzing Malfunctions Using Fault Trees
arXiv:2603.22978v1 Announce Type: new Abstract: In the maintenance of complex systems, fault trees are used to locate problems and provide targeted solutions. To enable fault trees stored as images to be directly processed by large language models, which can assist in tracking and analyzing malfunctions, we propose a novel textual representation of fault trees. Building on it, we construct a benchmark for multi-turn dialogue systems that emphasizes robust interaction in complex environments, ev
JFTA-Bench: Evaluate LLM's Ability of Tracking and Analyzing Malfunctions Using Fault Trees
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cs.AI, q-bio.NC updates on arXiv.org
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Kaleido: Open-Sourced Multi-Subject Reference Video Generation Model
arXiv:2510.18573v2 Announce Type: replace-cross Abstract: We present Kaleido, a subject-to-video~(S2V) generation framework, which aims to synthesize subject-consistent videos conditioned on multiple reference images of target subjects. Despite recent progress in S2V generation models, existing approaches remain inadequate at maintaining multi-subject consistency and at handling background disentanglement, often resulting in lower reference fidelity and semantic drift under multi-image conditio
Kaleido: Open-Sourced Multi-Subject Reference Video Generation Model
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cs.AI, q-bio.NC updates on arXiv.org
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Social-JEPA: Emergent Geometric Isomorphism
arXiv:2603.02263v1 Announce Type: cross Abstract: World models compress rich sensory streams into compact latent codes that anticipate future observations. We let separate agents acquire such models from distinct viewpoints of the same environment without any parameter sharing or coordination. After training, their internal representations exhibit a striking emergent property: the two latent spaces are related by an approximate linear isometry, enabling transparent translation between them. Thi
Social-JEPA: Emergent Geometric Isomorphism
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cs.AI, q-bio.NC updates on arXiv.org
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MolReasoner: Toward Effective and Interpretable Reasoning for Molecular LLMs
arXiv:2508.02066v2 Announce Type: replace-cross Abstract: Large Language Models (LLMs) have shown impressive performance across various domains, but their ability to perform molecular reasoning remains underexplored. Existing methods mostly rely on general-purpose prompting, which lacks domain-specific molecular semantics, or fine-tuning, which faces challenges in interpretability and reasoning depth, often leading to structural and textual hallucinations. To address these issues, we introduce
MolReasoner: Toward Effective and Interpretable Reasoning for Molecular LLMs
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cs.AI, q-bio.NC updates on arXiv.org
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LQA: A Lightweight Quantized-Adaptive Framework for Vision-Language Models on the Edge
arXiv:2602.07849v2 Announce Type: replace Abstract: Deploying Vision-Language Models (VLMs) on edge devices is challenged by resource constraints and performance degradation under distribution shifts. While test-time adaptation (TTA) can counteract such shifts, existing methods are too resource-intensive for on-device deployment. To address this challenge, we propose LQA, a lightweight, quantized-adaptive framework for VLMs that combines a modality-aware quantization strategy with gradient-free