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cs.AI, q-bio.NC updates on arXiv.org
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What Are We Actually Decoding? Source Attribution for Non-Invasive Brain-to-Language Retrieval
arXiv:2605.24524v1 Announce Type: cross Abstract: In non-invasive neural language decoding, results can be inflated by sources that are not stimulus-evoked neural evidence: decoder priors, embedding-based metrics, and non-neural structural nuisances such as signal duration. The methodological challenge is therefore attribution: a reported gain is more informative when it can be traced to a specific source. We recast stimulus-locked MEG-to-audio retrieval as an auditing framework that separates
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Nature - Issue - nature.com science feeds
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EBV strain interacts with host HLA to drive nasopharyngeal carcinoma risk
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10416-8A genome-to-genome association study identifies host and viral risk factors that interact to drive nasopharyngeal carcinoma endemicity in southern China.
EBV strain interacts with host HLA to drive nasopharyngeal carcinoma risk
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10416-8
A genome-to-genome association study identifies host and viral risk factors that interact to drive nasopharyngeal carcinoma endemicity in southern China.-
Omics in Gastric
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Mechanisms of Xinwei Tang in stress-induced gastric dysmotility: evidence from rat and In Vitro models
In Vitro Cell Dev Biol Anim. 2026 Mar 18. doi: 10.1007/s11626-026-01151-5. Online ahead of print.ABSTRACTStress is a key trigger of gastric dysmotility, partly via mitochondrial dysfunction and disordered gut-brain hormonal signaling. Xinwei Tang (XWT) is a multi-herb formula used empirically for upper gastrointestinal symptoms, but its mechanisms remain unclear. This study aimed to determine whether XWT alleviates water-immersion restraint stress (WIRS)-induced gastric dysmotility and to deline
Mechanisms of Xinwei Tang in stress-induced gastric dysmotility: evidence from rat and In Vitro models
In Vitro Cell Dev Biol Anim. 2026 Mar 18. doi: 10.1007/s11626-026-01151-5. Online ahead of print.
ABSTRACT
Stress is a key trigger of gastric dysmotility, partly via mitochondrial dysfunction and disordered gut-brain hormonal signaling. Xinwei Tang (XWT) is a multi-herb formula used empirically for upper gastrointestinal symptoms, but its mechanisms remain unclear. This study aimed to determine whether XWT alleviates water-immersion restraint stress (WIRS)-induced gastric dysmotility and to delineate underlying mitochondrial and metabolic pathways using integrated in vivo, in vitro and multi-omics approaches. Male rats underwent 7-d WIRS and received vehicle, domperidone (3 mg/kg) or XWT (3, 6, 12 g/kg). Gastric emptying, serum motilin/gastrin, oxidative stress indices and PINK1/Parkin-LC3/p62 proteins were assessed, and H₂O₂-injured GES-1 cells were treated with XWT-medicated serum. Gastric antra from MOD and XWT-H rats were analyzed by RNA-seq and DIA proteomics (n = 3/group). WIRS reduced gastric emptying by roughly half and lowered motilin/gastrin, increased ROS/MDA and disrupted PINK1/Parkin-LC3/p62 profiles; XWT dose-dependently reversed these changes, with XWT-H approximating domperidone. Omics revealed XWT-associated downregulation of inflammatory/protease and acute-phase genes/proteins and enrichment of oxidative phosphorylation, tricarboxylic-acid cycle and other metabolic pathways, without global activation of canonical autophagy/mitophagy gene sets. These preclinical data indicate that XWT ameliorates stress-induced gastric dysmotility via mitochondria- and metabolism-centred protection with selective tuning of mitophagy-related proteins.
PMID:41851413 | DOI:10.1007/s11626-026-01151-5