Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10416-8

A genome-to-genome association study identifies host and viral risk factors that interact to drive nasopharyngeal carcinoma endemicity in southern China.

arXiv:2604.01988v1 Announce Type: new Abstract: Large language models often default to step-by-step computation even when efficient numerical shortcuts are available. This raises a basic question: do they exhibit number sense in a human-like behavioral sense, i.e., the ability to recognize numerical structure, apply shortcuts when appropriate, and avoid them when they are not? We introduce SenseMath, a controlled benchmark for evaluating structure-sensitive numerical reasoning in LLMs. SenseMath contains 4,800 items spanning eight shortcut categories and four digit scales, with matched strong-shortcut, weak-shortcut, and control variants. It supports three evaluation settings of increasing cognitive demand: Shortcut Use (whether models can apply shortcuts on shortcut-amenable problems); Applicability Judgment (whether they can recognize when a shortcut is appropriate or misleading); and Problem Generation (whether they can generate new problem items that correctly admit a given type of shortcut). Our evaluation across five LLMs, ranging from GPT-4o-mini to Llama-3.1-8B, shows a consistent pattern: when explicitly prompted, models readily adopt shortcut strategies and achieve substantial accuracy gains on shortcut-amenable items (up to 15%), yet under standard chain-of-thought prompting they spontaneously employ such strategies in fewer than 40% of cases, even when they demonstrably possess the requisite capability. Moreover, this competence is confined to the Use level; models systematically over-generalise shortcuts to problems where they do not apply, and fail to generate valid shortcut-bearing problems from scratch. Together, these results suggest that current LLMs exhibit procedural shortcut fluency without the structural understanding of when and why shortcuts work that underlies human number sense.

arXiv:2604.02296v1 Announce Type: cross Abstract: Existing video object removal methods excel at inpainting content "behind" the object and correcting appearance-level artifacts such as shadows and reflections. However, when the removed object has more significant interactions, such as collisions with other objects, current models fail to correct them and produce implausible results. We present VOID, a video object removal framework designed to perform physically-plausible inpainting in these complex scenarios. To train the model, we generate a new paired dataset of counterfactual object removals using Kubric and HUMOTO, where removing an object requires altering downstream physical interactions. During inference, a vision-language model identifies regions of the scene affected by the removed object. These regions are then used to guide a video diffusion model that generates physically consistent counterfactual outcomes. Experiments on both synthetic and real data show that our approach better preserves consistent scene dynamics after object removal compared to prior video object removal methods. We hope this framework sheds light on how to make video editing models better simulators of the world through high-level causal reasoning.

arXiv:2508.03346v2 Announce Type: replace Abstract: Large Language Models (LLMs) using Chain-of-Thought (CoT) prompting excel at complex reasoning but generate verbose thought processes with considerable redundancy, leading to increased inference costs and reduced efficiency. We introduce a novel CoT compression framework based on step entropy, a metric that quantifies \emph{the informational contribution of individual reasoning steps} to identify redundancy. Through theoretical analysis and extensive empirical validation on mathematical reasoning benchmarks, we demonstrate that steps with low entropy are indeed highly redundant. Our experiments reveal that an astonishing 80\% of low-entropy intermediate steps can be pruned with minor degradation in the final answer accuracy across DeepSeek-R1-7B, 14B and Qwen3-8B. This finding sharply contrasts with random or high-entropy pruning, which severely impairs reasoning performance. Building on this, we propose a novel two-stage training strategy combining Supervised Fine-Tuning (SFT) and Group Relative Policy Optimization (GRPO) reinforcement learning. This approach enables LLMs to autonomously learn to generate compressed COTs during inference by strategically incorporating [SKIP] tokens. Our method significantly improves LLM inference efficiency while preserving accuracy, paving the way for more scalable LLM deployments and a better understanding of their internal reasoning. The code and data are released in https://github.com/staymylove/COT_Compresstion_via_Step_entropy.