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TAG: Thinking with Action Unit Grounding for Facial Expression Recognition

arXiv:2602.18763v1 Announce Type: cross Abstract: Facial Expression Recognition (FER) is a fine-grained visual understanding task where reliable predictions require reasoning over localized and meaningful facial cues. Recent vision--language models (VLMs) enable natural language explanations for FER, but their reasoning is often ungrounded, producing fluent yet unverifiable rationales that are weakly tied to visual evidence and prone to hallucination, leading to poor robustness across different datasets. We propose TAG (Thinking with Action Unit Grounding), a vision--language framework that explicitly constrains multimodal reasoning to be supported by facial Action Units (AUs). TAG requires intermediate reasoning steps to be grounded in AU-related facial regions, yielding predictions accompanied by verifiable visual evidence. The model is trained via supervised fine-tuning on AU-grounded reasoning traces followed by reinforcement learning with an AU-aware reward that aligns predicted regions with external AU detectors. Evaluated on RAF-DB, FERPlus, and AffectNet, TAG consistently outperforms strong open-source and closed-source VLM baselines while simultaneously improving visual faithfulness. Ablation and preference studies further show that AU-grounded rewards stabilize reasoning and mitigate hallucination, demonstrating the importance of structured grounded intermediate representations for trustworthy multimodal reasoning in FER. The code will be available at https://github.com/would1920/FER_TAG .

AI-driven Large-scale Electron Microscopy enables Whole-tissue Subcellular Digitization

By: Li Xiao Β· Liqing Liu Β· Hongjun Wu Β· Jiayi Zhong Β· Xixia Li Β· Yan Zhang Β· Junjie Hu Β· Sun Fei Β· Ge Yang Β· Tao Xu
24 February 2026 at 13:00
arXiv:2511.02860v2 Announce Type: replace-cross Abstract: The distribution and interactions of cellular organelles play a critical role in mediating cellular physiology and pathology. Large-scale electron microscopy enables visualization of organelle distribution and interactions at the tissue level with nanometer resolution, but robust and efficient computational analysis tools are lacking. Here, we present a deep learning tool for universal large-scale 2D/3D electron microscopy analysis, DeepOrganelle. This new tool enables high-throughput, cell-resolved spatiotemporal mapping and digitization of organelle distribution and interactions. When applied to spermatogenesis across 12 stages and 22 differentiation status of the germ cells, DeepOrganelle uncovered previously unrecognized, stage-dependent dynamics of mitochondria-endoplasmic reticulum contact sites within one subphase of prophase I during meiosis. It also revealed coordinated organelle redistribution in Sertoli cells towards the blood-testis barrier, digitizing the remodeling dynamics of the tissue. This study demonstrates that DeepOrganelle provides a powerful framework that captures subcellular dynamics at the whole-tissue level.
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