arXiv:2603.07365v1 Announce Type: cross Abstract: Neural scaling laws describe how model performance improves as a power law with size, but existing work focuses on models above 100M parameters. The sub-20M regime -- where TinyML and edge AI operate -- remains unexamined. We train 90 models (22K--19.8M parameters) across two architectures (plain ConvNet, MobileNetV2) on CIFAR-100, varying width while holding depth and training fixed. Both follow approximate power laws in error rate: $\alpha = 0.156 \pm 0.002$ (ScaleCNN) and $\alpha = 0.106 \pm 0.001$ (MobileNetV2) across five seeds. Since prior work fit cross-entropy loss rather than error rate, direct exponent comparison is approximate; with that caveat, these are 1.4--2x steeper than $\alpha \approx 0.076$ for large language models. The power law does not hold uniformly: local exponents decay with scale, and MobileNetV2 saturates at 19.8M parameters ($\alpha_{\mathrm{local}} = 0.006$). Error structure also changes. Jaccard overlap between error sets of the smallest and largest ScaleCNN is only 0.35 (25 seed pairs, $\pm 0.004$) -- compression changes which inputs are misclassified, not merely how many. Small models concentrate capacity on easy classes (Gini: 0.26 at 22K vs. 0.09 at 4.7M) while abandoning the hardest (bottom-5 accuracy: 10% vs. 53%). Counter to expectation, the smallest models are best calibrated (ECE = 0.013 vs. peak 0.110 at mid-size). Aggregate accuracy is therefore misleading for edge deployment; validation must happen at the target model size.

arXiv:2603.08304v1 Announce Type: cross Abstract: This work addresses the accurate and efficient simulation of physical phenomena governed by parametric Partial Differential Equations (PDEs) characterized by varying boundary conditions, where parametric instances modify not only the physics of the problem but also the imposition of boundary constraints on the computational domain. In such scenarios, classical Galerkin projection-based reduced order techniques encounter a fundamental bottleneck. Parametric boundaries typically necessitate a re-formulation of the discrete problem for each new configuration, and often, these approaches are unsuitable for real-time applications. To overcome these limitations, we propose a novel methodology based on Graph-Instructed Neural Networks (GINNs). The GINN framework effectively learns the mapping between the parametric description of the computational domain and the corresponding PDE solution. Our results demonstrate that the proposed GINN-based models, can efficiently represent highly complex parametric PDEs, serving as a robust and scalable asset for several applied-oriented settings when compared with fully connected architectures.

arXiv:2603.08305v1 Announce Type: cross Abstract: Text-conditioned generative models for volumetric medical imaging provide semantic control but lack explicit anatomical guidance, often resulting in outputs that are spatially ambiguous or anatomically inconsistent. In contrast, structure-driven methods ensure strong anatomical consistency but typically assume access to ground-truth annotations, which are unavailable when the target image is to be synthesized. We propose a retrieval-augmented approach for Text-to-CT generation that integrates semantic and anatomical information under a realistic inference setting. Given a radiology report, our method retrieves a semantically related clinical case using a 3D vision-language encoder and leverages its associated anatomical annotation as a structural proxy. This proxy is injected into a text-conditioned latent diffusion model via a ControlNet branch, providing coarse anatomical guidance while maintaining semantic flexibility. Experiments on the CT-RATE dataset show that retrieval-augmented generation improves image fidelity and clinical consistency compared to text-only baselines, while additionally enabling explicit spatial controllability, a capability inherently absent in such approaches. Further analysis highlights the importance of retrieval quality, with semantically aligned proxies yielding consistent gains across all evaluation axes. This work introduces a principled and scalable mechanism to bridge semantic conditioning and anatomical plausibility in volumetric medical image synthesis. Code will be released.

arXiv:2602.22758v2 Announce Type: replace Abstract: We decompose physician disagreement in the HealthBench medical AI evaluation dataset to understand where variance resides and what observable features can explain it. Rubric identity accounts for 15.8% of met/not-met label variance but only 3.6-6.9% of disagreement variance; physician identity accounts for just 2.4%. The dominant 81.8% case-level residual is not reduced by HealthBench's metadata labels (z = -0.22, p = 0.83), normative rubric language (pseudo R^2 = 1.2%), medical specialty (0/300 Tukey pairs significant), surface-feature triage (AUC = 0.58), or embeddings (AUC = 0.485). Disagreement follows an inverted-U with completion quality (AUC = 0.689), confirming physicians agree on clearly good or bad outputs but split on borderline cases. Physician-validated uncertainty categories reveal that reducible uncertainty (missing context, ambiguous phrasing) more than doubles disagreement odds (OR = 2.55, p

arXiv:2508.02879v3 Announce Type: replace-cross Abstract: Time series foundation models (TSFMs) have recently gained significant attention due to their strong zero-shot capabilities and widespread real-world applications. Such models typically require a computationally costly pre-training on large-scale, carefully curated collections of real-world sequences. To allow for a sample-efficient pre-training of TSFMs, we propose \textsc{CauKer}, a novel algorithm designed to generate diverse, causally coherent synthetic time series with realistic trends, seasonality, and nonlinear interactions. \textsc{CauKer} combines Gaussian Process (GP) kernel composition with Structural Causal Models (SCM) to produce data for sample-efficient pre-training of state-of-the-art classification TSFMs having different architectures and following different pre-training approaches. Additionally, our experiments reveal that \textsc{CauKer}-generated datasets exhibit clear scaling laws for both dataset size (10K to 10M samples) and model capacity (1M to 783M parameters), unlike real-world datasets, which display irregular scaling behavior. The source code is publicly available at https://github.com/ShifengXIE/CauKer.

arXiv:2511.18694v2 Announce Type: replace-cross Abstract: Stable and accurate tracking is essential for marine robotics, yet Global Navigation Satellite System (GNSS) signals vanish immediately below the sea surface. Traditional alternatives suffer from error accumulation, high computational demands, or infrastructure dependence. In this work, we present a multi-drone GNSS-based tracking system for surface and near-surface marine robots. Our approach combines efficient visual detection, lightweight multi-object tracking, GNSS-based triangulation, and a confidence-weighted Extended Kalman Filter (EKF) to provide stable GNSS estimation in real time. We further introduce a cross-drone tracking ID alignment algorithm that enforces global consistency across views, enabling robust multi-robot tracking with cooperative aerial coverage. We validate our system in diversified complex settings to show the accuracy and robustness of the proposed algorithm.

arXiv:2512.16848v2 Announce Type: replace-cross Abstract: Reinforcement learning (RL) has enabled the training of large language model (LLM) agents to interact with the environment and to solve multi-turn long-horizon tasks. However, the RL-trained agents often struggle in tasks that require active exploration and fail to efficiently adapt from trial-and-error experiences. In this paper, we present LaMer, a general Meta-RL framework that enables LLM agents to actively explore and learn from the environment feedback at test time. LaMer consists of two key components: (i) a cross-episode training framework to encourage exploration and long-term rewards optimization; and (ii) in-context policy adaptation via reflection, allowing the agent to adapt their policy from task feedback signal without gradient update. Experiments across diverse environments show that LaMer significantly improves performance over RL baselines, with 11%, 14%, and 19% performance gains on Sokoban, MineSweeper and Webshop, respectively. Moreover, LaMer also demonstrates better generalization to more challenging or previously unseen tasks compared to the RL-trained agents. Overall, our results demonstrate that Meta-RL provides a principled approach to induce exploration in language agents, enabling more robust adaptation to novel environments through learned exploration strategies.

arXiv:2601.19940v2 Announce Type: replace-cross Abstract: Among hardware accelerators for deep-learning inference, data flow implementations offer low latency and high throughput capabilities. In these architectures, each neuron is mapped to a dedicated hardware unit, making them well-suited for field-programmable gate array (FPGA) implementation. Previous unrolled implementations mostly focus on fully connected networks because of their simplicity, although it is well known that convolutional neural networks (CNNs) require fewer computations for the same accuracy. When observing the data flow in CNNs, pooling layers and convolutional layers with a stride larger than one, the number of data at their output is reduced with respect to their input. This data reduction strongly affects the data rate in a fully parallel implementation, making hardware units heavily underutilized unless it is handled properly. This work addresses this issue by analyzing the data flow of CNNs and presents a novel approach to designing data-rate-aware, continuous-flow CNN architectures. The proposed approach ensures a high hardware utilization close to 100% by interleaving low data rate signals and sharing hardware units, as well as using the right parallelization to achieve the throughput of a fully parallel implementation. The results show that a significant amount of the arithmetic logic can be saved, which allows implementing complex CNNs like MobileNet on a single FPGA with high throughput.

Nature, Published online: 10 March 2026; doi:10.1038/d41586-026-00778-4

Prevent pandemics through One Health commitments

Oncogenesis, Published online: 07 March 2026; doi:10.1038/s41389-026-00606-4

C1s protects cutaneous squamous carcinoma cells from TRAIL-induced apoptosis

arXiv:2603.04149v1 Announce Type: new Abstract: Structural and functional heterogeneity are hallmarks of cortical circuits, from broad degree distributions in the mouse connectome to diverse intrinsic neuronal timescales. Yet a mechanistic link between connectivity heterogeneity and functional diversity is lacking. To bridge this gap, we introduce a random recurrent network in which connectivity is generated by a configuration model with tunable degree heterogeneity and synaptic weights exhibiting varying levels of correlation. Using generating-functional methods, we derive a heterogeneous dynamical mean-field theory (hDMFT) with degree-conditioned stochastic dynamics. The theory shows that the interaction of partial symmetry in the weights and degree heterogeneity induces a non-Markovian memory term in the form of an emergent self-coupling whose strength scales with degree and produces a broad distribution of activity timescales. We obtain analytic stability criteria demonstrating that degree heterogeneity lowers the critical gain and localizes unstable modes onto hubs. The resulting rich dynamical landscape includes silent, chaotic, and multistable regimes, which we uncover via spectral, replica, and Lyapunov exponent analyses. We highlight the computational benefits of the observed timescale heterogeneity by revealing that, under an external input drive featuring a broadband spectrum, slow hub neurons act as integrators, demixing slow input components. Finally, instantiating the model with the empirically measured topology from the MICrONS cubic-millimeter mouse connectome explains the broad range of single-neuron timescales and their positive correlation with in-degree observed in resting-state recordings. Our results provide a mechanistic link between connectome topology, neural dynamics, and computation, identifying hubs in partially symmetric networks as a natural substrate for multiplexed processing across timescales.

arXiv:2507.15796v2 Announce Type: replace Abstract: Federated Learning (FL) enables privacy-preserving collaborative learning, yet deployments increasingly show that privacy guarantees alone do not sustain trust in high-risk settings. As FL systems move toward agentic AI, large language model-enabled, and dynamically adaptive architectures, trustworthiness becomes a system-level problem shaped by autonomous decision-making, non-stationary environments, and multi-stakeholder governance. We argue for Trustworthy FL (TFL), treating trust as a continuously maintained operating condition rather than a static model property. Through the lens of Trust Report 2.0, we propose a requirement-driven taxonomy of challenges grounded in TAI and explicitly extended to account for control-plane decisions, agency, and system dynamics across the federated lifecycle. Building on this diagnosis, we introduce a coordination blueprint that structures cross-requirement trade-offs, decision justification, and governance alignment in TFL systems. To operationalize assurance, Trust Report 2.0 is instantiated as a lightweight, privacy-preserving artifact that surfaces decision-centric trust evidence without centralizing raw data. We illustrate applicability via healthcare as a stress-test domain, focusing on oncology FL under regulatory pressure and clinical risk.

arXiv:2405.01440v3 Announce Type: replace-cross Abstract: Reinforcement learning has emerged as an important approach for autonomous driving. A reward function is used in reinforcement learning to establish the learned skill objectives and guide the agent toward the optimal policy. Since autonomous driving is a complex domain with partly conflicting objectives with varying degrees of priority, developing a suitable reward function represents a fundamental challenge. This paper aims to highlight the gap in such function design by assessing different proposed formulations in the literature and dividing individual objectives into Safety, Comfort, Progress, and Traffic Rules compliance categories. Additionally, the limitations of the reviewed reward functions are discussed, such as objectives aggregation and indifference to driving context. Furthermore, the reward categories are frequently inadequately formulated and lack standardization. This paper concludes by proposing future research that potentially addresses the observed shortcomings in rewards, including a reward validation framework and structured rewards that are context-aware and able to resolve conflicts.

arXiv:2406.06512v2 Announce Type: replace-cross Abstract: The large volume of abdominal computed tomography (CT) scans coupled with the shortage of radiologists have intensified the need for automated medical image analysis tools. Previous state-of-the-art approaches for automated analysis leverage vision-language models (VLMs) that jointly model images and radiology reports. However, current medical VLMs are generally limited to 2D images and short reports. Here to overcome these shortcomings for abdominal CT interpretation, we introduce Merlin, a 3D VLM that learns from volumetric CT scans, electronic health record data and radiology reports. This approach is enabled by a multistage pretraining framework that does not require additional manual annotations. We trained Merlin using a high-quality clinical dataset of paired CT scans (>6 million images from 15,331 CT scans), diagnosis codes (>1.8 million codes) and radiology reports (>6 million tokens). We comprehensively evaluated Merlin on 6 task types and 752 individual tasks that covered diagnostic, prognostic and quality-related tasks. The non-adapted (off-the-shelf) tasks included zero-shot classification of findings (30 findings), phenotype classification (692 phenotypes) and zero-shot cross-modal retrieval (image-to-findings and image-to-impression). The model-adapted tasks included 5-year chronic disease prediction (6 diseases), radiology report generation and 3D semantic segmentation (20 organs). We validated Merlin at scale, with internal testing on 5,137 CT scans and external testing on 44,098 CT scans from 3 independent sites and 2 public datasets. The results demonstrated high generalization across institutions and anatomies. Merlin outperformed 2D VLMs, CT foundation models and off-the-shelf radiology models. We also release our trained models, code, and dataset, available at: https://github.com/StanfordMIMI/Merlin.

arXiv:2505.06743v4 Announce Type: replace-cross Abstract: Trajectory prediction is crucial for autonomous driving, enabling vehicles to navigate safely by anticipating the movements of surrounding road users. However, current deep learning models often lack trustworthiness as their predictions can be physically infeasible and illogical to humans. To make predictions more trustworthy, recent research has incorporated prior knowledge, like the social force model for modeling interactions and kinematic models for physical realism. However, these approaches focus on priors that suit either vehicles or pedestrians and do not generalize to traffic with mixed agent classes. We propose incorporating interaction and kinematic priors of all agent classes--vehicles, pedestrians, and cyclists with class-specific interaction layers to capture agent behavioral differences. To improve the interpretability of the agent interactions, we introduce DG-SFM, a rule-based interaction importance score that guides the interaction layer. To ensure physically feasible predictions, we proposed suitable kinematic models for all agent classes with a novel pedestrian kinematic model. We benchmark our approach on the Argoverse 2 dataset, using the state-of-the-art transformer HPTR as our baseline. Experiments demonstrate that our method improves interaction interpretability, revealing a correlation between incorrect predictions and divergence from our interaction prior. Even though incorporating the kinematic models causes a slight decrease in accuracy, they eliminate infeasible trajectories found in the dataset and the baseline model. Thus, our approach fosters trust in trajectory prediction as its interaction reasoning is interpretable, and its predictions adhere to physics.

arXiv:2505.16985v2 Announce Type: replace-cross Abstract: Out-of-distribution (OOD) detection and segmentation are crucial for deploying machine learning models in safety-critical applications such as autonomous driving and robot-assisted surgery. While prior research has primarily focused on unimodal image data, real-world applications are inherently multimodal, requiring the integration of multiple modalities for improved OOD detection. A key challenge is the lack of supervision signals from unknown data, leading to overconfident predictions on OOD samples. To address this challenge, we propose Feature Mixing, an extremely simple and fast method for multimodal outlier synthesis with theoretical support, which can be further optimized to help the model better distinguish between in-distribution (ID) and OOD data. Feature Mixing is modality-agnostic and applicable to various modality combinations. Additionally, we introduce CARLA-OOD, a novel multimodal dataset for OOD segmentation, featuring synthetic OOD objects across diverse scenes and weather conditions. Extensive experiments on SemanticKITTI, nuScenes, CARLA-OOD datasets, and the MultiOOD benchmark demonstrate that Feature Mixing achieves state-of-the-art performance with a $10 \times$ to $370 \times$ speedup. Our source code and dataset will be available at https://github.com/mona4399/FeatureMixing.

arXiv:2603.02297v1 Announce Type: cross Abstract: Large language models (LLMs) are increasingly being deployed as software engineering agents that autonomously contribute to repositories. A major benefit these agents present is their ability to find and patch security vulnerabilities in the codebases they oversee. To estimate the capability of agents in this domain, we introduce ZeroDayBench, a benchmark where LLM agents find and patch 22 novel critical vulnerabilities in open-source codebases. We focus our efforts on three popular frontier agentic LLMs: GPT-5.2, Claude Sonnet 4.5, and Grok 4.1. We find that frontier LLMs are not yet capable of autonomously solving our tasks and observe some behavioral patterns that suggest how these models can be improved in the domain of proactive cyberdefense.

arXiv:2603.02345v1 Announce Type: cross Abstract: Infrastructure as code (IaC) tools automate cloud provisioning but verifying that deployed systems remain consistent with the IaC specifications remains challenging. Such configuration drift occurs because of bugs in the IaC specification, manual changes, or system updates. Large language model (LLM)-based agentic AI systems can automate the analysis of large volumes of telemetry data, making them suitable for the detection of configuration drift. However, existing agentic systems implicitly assume that the tools they invoke always return correct outputs, making them vulnerable to erroneous tool responses. Since agents cannot distinguish whether an anomalous tool output reflects a real infrastructure problem or a broken tool, such errors may cause missed drift or false alarms, reducing reliability precisely when it is most needed. We introduce RIVA (Robust Infrastructure by Verification Agents), a novel multi-agent system that performs robust IaC verification even when tools produce incorrect or misleading outputs. RIVA employs two specialized agents, a verifier agent and a tool generation agent, that collaborate through iterative cross-validation, multi-perspective verification, and tool call history tracking. Evaluation on the AIOpsLab benchmark demonstrates that RIVA, in the presence of erroneous tool responses, recovers task accuracy from 27.3% when using a baseline ReAct agent to 50.0% on average. RIVA also improves task accuracy 28% to 43.8% without erroneous tool responses. Our results show that cross-validation of diverse tool calls enables more reliable autonomous infrastructure verification in production cloud environments.

arXiv:2603.02638v1 Announce Type: cross Abstract: Machine learning for mobile network analysis, planning, and optimization is often limited by the lack of large, comprehensive real-world datasets. This paper introduces the Vienna 4G/5G Drive-Test Dataset, a city-scale open dataset of georeferenced Long Term Evolution (LTE) and 5G New Radio (NR) measurements collected across Vienna, Austria. The dataset combines passive wideband scanner observations with active handset logs, providing complementary network-side and user-side views of deployed radio access networks. The measurements cover diverse urban and suburban settings and are aligned with time and location information to support consistent evaluation. For a representative subset of base stations (BSs), we provide inferred deployment descriptors, including estimated BS locations, sector azimuths, and antenna heights. The release further includes high-resolution building and terrain models, enabling geometry-conditioned learning and calibration of deterministic approaches such as ray tracing. To facilitate practical reuse, the data are organized into scanner, handset, estimated cell information, and city-model components, and the accompanying documentation describes the available fields and intended joins between them. The dataset enables reproducible benchmarking across environment-aware learning, propagation modeling, coverage analysis, and ray-tracing calibration workflows.

arXiv:2503.14572v4 Announce Type: replace-cross Abstract: The capacity of foundation models allows for their application to new, unseen tasks. The adaptation to such tasks is called transfer learning. An efficient transfer learning method that circumvents parameter optimization is imprinting. The conceptual differences between studies on imprinting form the basis of our systematic investigation. In this work, we propose the general \texttt{IMPRINT} framework, identifying three main components: generation, normalization, and aggregation. Through the lens of this framework, we conduct an in-depth analysis and a comparison of the existing methods. Our findings reveal the benefits of representing novel data with multiple proxies in the generation step and show the importance of proper normalization. Beyond an extensive analytical grounding, our framework enables us to propose a novel variant of imprinting which outperforms previous work on transfer learning tasks by 4\%. This variant determines proxies through clustering motivated by the neural collapse phenomenon -- a connection that we draw for the first time. We publicly release our code at https://github.com/DATEXIS/IMPRINT.