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DECADE: A Temporally-Consistent Unsupervised Diffusion Model for Enhanced Rb-82 Dynamic Cardiac PET Image Denoising

arXiv:2603.07759v1 Announce Type: cross Abstract: Rb-82 dynamic cardiac PET imaging is widely used for the clinical diagnosis of coronary artery disease (CAD), but its short half-life results in high noise levels that degrade dynamic frame quality and parametric imaging. The lack of paired clean-noisy training data, rapid tracer kinetics, and frame-dependent noise variations further limit the effectiveness of existing deep learning denoising methods. We propose DECADE (A Temporally-Consistent Unsupervised Diffusion model for Enhanced Rb-82 CArdiac PET DEnoising), an unsupervised diffusion framework that generalizes across early- to late-phase dynamic frames. DECADE incorporates temporal consistency during both training and iterative sampling, using noisy frames as guidance to preserve quantitative accuracy. The method was trained and evaluated on datasets acquired from Siemens Vision 450 and Siemens Biograph Vision Quadra scanners. On the Vision 450 dataset, DECADE consistently produced high-quality dynamic and parametric images with reduced noise while preserving myocardial blood flow (MBF) and myocardial flow reserve (MFR). On the Quadra dataset, using 15%-count images as input and full-count images as reference, DECADE outperformed UNet-based and other diffusion models in image quality and K1/MBF quantification. The proposed framework enables effective unsupervised denoising of Rb-82 dynamic cardiac PET without paired training data, supporting clearer visualization while maintaining quantitative integrity.

Scores Know Bobs Voice: Speaker Impersonation Attack

arXiv:2603.02781v1 Announce Type: cross Abstract: Advances in deep learning have enabled the widespread deployment of speaker recognition systems (SRSs), yet they remain vulnerable to score-based impersonation attacks. Existing attacks that operate directly on raw waveforms require a large number of queries due to the difficulty of optimizing in high-dimensional audio spaces. Latent-space optimization within generative models offers improved efficiency, but these latent spaces are shaped by data distribution matching and do not inherently capture speaker-discriminative geometry. As a result, optimization trajectories often fail to align with the adversarial direction needed to maximize victim scores. To address this limitation, we propose an inversion-based generative attack framework that explicitly aligns the latent space of the synthesis model with the discriminative feature space of SRSs. We first analyze the requirements of an inverse model for score-based attacks and introduce a feature-aligned inversion strategy that geometrically synchronizes latent representations with speaker embeddings. This alignment ensures that latent updates directly translate into score improvements. Moreover, it enables new attack paradigms, including subspace-projection-based attacks, which were previously infeasible due to the absence of a faithful feature-to-audio mapping. Experiments show that our method significantly improves query efficiency, achieving competitive attack success rates with on average 10x fewer queries than prior approaches. In particular, the enabled subspace-projection-based attack attains up to 91.65% success using only 50 queries. These findings establish feature-aligned inversion as a key tool for evaluating the robustness of modern SRSs against score-based impersonation threats.
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