arXiv:2603.22317v1 Announce Type: cross Abstract: Graph-structured data typically exhibits complex topological heterogeneity, making it difficult to model accurately within a single Riemannian manifold. While emerging mixed-curvature methods attempt to capture such diversity, they often rely on implicit, task-driven routing that lacks fundamental geometric grounding. To address this challenge, we propose a Geometric Mixture-of-Experts framework (GeoMoE) that adaptively fuses node representations across diverse Riemannian spaces to better accommodate multi-scale topological structures. At its core, GeoMoE leverages Ollivier-Ricci Curvature (ORC) as an intrinsic geometric prior to orchestrate the collaboration of specialized experts. Specifically, we design a graph-aware gating network that assigns node-specific fusion weights, regularized by a curvature-guided alignment loss to ensure interpretable and geometry-consistent routing. Additionally, we introduce a curvature-aware contrastive objective that promotes geometric discriminability by constructing positive and negative pairs according to curvature consistency. Extensive experiments on six benchmark datasets demonstrate that GeoMoE outperforms state-of-the-art baselines across diverse graph types.

Cell Death Discovery, Published online: 14 March 2026; doi:10.1038/s41420-026-02954-x

SOX4 induces cisplatin resistance in cervical cancer cells by inhibiting aerobic glycolysis

arXiv:2603.03782v1 Announce Type: cross Abstract: Shared-account usage is common on streaming and e-commerce platforms, where multiple users share one account. Existing shared-account sequential recommendation (SSR) methods often assume a fixed number of latent users per account, limiting their ability to adapt to diverse sharing patterns and reducing recommendation accuracy. Recent latent reasoning technique applied in sequential recommendation (SR) generate intermediate embeddings from the user embedding (e.g, last item embedding) to uncover users' potential interests, which inspires us to treat the problem of inferring the number of latent users as generating a series of intermediate embeddings, shifting from inferring preferences behind user to inferring the users behind account. However, the last item cannot be directly used for reasoning in SSR, as it can only represent the behavior of the most recent latent user, rather than the collective behavior of the entire account. To address this, we propose DisenReason, a two-stage reasoning method tailored to SSR. DisenReason combines behavior disentanglement stage from frequency-domain perspective to create a collective and unified account behavior representation, which serves as a pivot for latent user reasoning stage to infer the number of users behind the account. Experiments on four benchmark datasets show that DisenReason consistently outperforms all state-of-the-art baselines across four benchmark datasets, achieving relative improvements of up to 12.56\% in MRR@5 and 6.06\% in Recall@20.