Normal view
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cs.AI, q-bio.NC updates on arXiv.org
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Learning Contextual Runtime Monitors for Safe AI-Based Autonomy
arXiv:2601.20666v3 Announce Type: replace-cross Abstract: We introduce a novel framework for learning context-aware runtime monitors for AI-based control ensembles. Machine-learning (ML) controllers are increasingly deployed in (autonomous) cyber-physical systems because of their ability to solve complex decision-making tasks. However, their accuracy can degrade sharply in unfamiliar environments, creating significant safety concerns. Traditional ensemble methods aim to improve robustness by av
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cs.AI, q-bio.NC updates on arXiv.org
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Do Phone-Use Agents Respect Your Privacy?
arXiv:2604.00986v2 Announce Type: replace-cross Abstract: We study whether phone-use agents respect privacy while completing benign mobile tasks. This question has remained hard to answer because privacy-compliant behavior is not operationalized for phone-use agents, and ordinary apps do not reveal exactly what data agents type into which form entries during execution. To make this question measurable, we introduce MyPhoneBench, a verifiable evaluation framework for privacy behavior in mobile a
Do Phone-Use Agents Respect Your Privacy?
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cs.AI, q-bio.NC updates on arXiv.org
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Ran Score: a LLM-based Evaluation Score for Radiology Report Generation
arXiv:2603.22935v1 Announce Type: new Abstract: Chest X-ray report generation and automated evaluation are limited by poor recognition of low-prevalence abnormalities and inadequate handling of clinically important language, including negation and ambiguity. We develop a clinician-guided framework combining human expertise and large language models for multi-label finding extraction from free-text chest X-ray reports and use it to define Ran Score, a finding-level metric for report evaluation.
Ran Score: a LLM-based Evaluation Score for Radiology Report Generation
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cs.AI, q-bio.NC updates on arXiv.org
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Set-Valued Prediction for Large Language Models with Feasibility-Aware Coverage Guarantees
arXiv:2603.22966v1 Announce Type: cross Abstract: Large language models (LLMs) inherently operate over a large generation space, yet conventional usage typically reports the most likely generation (MLG) as a point prediction, which underestimates the model's capability: although the top-ranked response can be incorrect, valid answers may still exist within the broader output space and can potentially be discovered through repeated sampling. This observation motivates moving from point predictio
Set-Valued Prediction for Large Language Models with Feasibility-Aware Coverage Guarantees
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cs.AI, q-bio.NC updates on arXiv.org
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From Editor to Dense Geometry Estimator
arXiv:2509.04338v2 Announce Type: replace-cross Abstract: Leveraging visual priors from pre-trained text-to-image (T2I) generative models has shown success in dense prediction. However, dense prediction is inherently an image-to-image task, suggesting that image editing models, rather than T2I generative models, may be a more suitable foundation for fine-tuning. Motivated by this, we conduct a systematic analysis of the fine-tuning behaviors of both editors and generators for dense geometry e
From Editor to Dense Geometry Estimator
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cs.AI, q-bio.NC updates on arXiv.org
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FlyPrompt: Brain-Inspired Random-Expanded Routing with Temporal-Ensemble Experts for General Continual Learning
arXiv:2602.01976v3 Announce Type: replace-cross Abstract: General continual learning (GCL) challenges intelligent systems to learn from single-pass, non-stationary data streams without clear task boundaries. While recent advances in continual parameter-efficient tuning (PET) of pretrained models show promise, they typically rely on multiple training epochs and explicit task cues, limiting their effectiveness in GCL scenarios. Moreover, existing methods often lack targeted design and fail to add
FlyPrompt: Brain-Inspired Random-Expanded Routing with Temporal-Ensemble Experts for General Continual Learning
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Pulmonary nodule
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NFATC2::NUTM2 Fusion Defines a Novel Primary Pulmonary Epithelial Tumor With a Distinctive Immunophenotype
Am J Surg Pathol. 2026 Jun 1;50(6):695-704. doi: 10.1097/PAS.0000000000002533. Epub 2026 Mar 13.ABSTRACTWith the application of molecular techniques in pathologic diagnosis, several novel primary pulmonary epithelial tumors have been continuously discovered and classified under the WHO classification of thoracic tumors. Recently, a pulmonary tumor with NFATC2 :: NUTM2B fusion was first documented, but the spectrum of NFATC2::NUTM2 fusion variants and their associated pathologic features remains
NFATC2::NUTM2 Fusion Defines a Novel Primary Pulmonary Epithelial Tumor With a Distinctive Immunophenotype
Am J Surg Pathol. 2026 Jun 1;50(6):695-704. doi: 10.1097/PAS.0000000000002533. Epub 2026 Mar 13.
ABSTRACT
With the application of molecular techniques in pathologic diagnosis, several novel primary pulmonary epithelial tumors have been continuously discovered and classified under the WHO classification of thoracic tumors. Recently, a pulmonary tumor with NFATC2 :: NUTM2B fusion was first documented, but the spectrum of NFATC2::NUTM2 fusion variants and their associated pathologic features remains incompletely characterized. Coincidentally, we also found and described 6 primary pulmonary tumors harboring recurrent NFATC2::NUTM2A/E fusions through integrated genomic analysis. These patients, including 4 females and 2 males, with a median age of 53 years, presented with incidentally detected peripheral lung nodules composed of monotonous epithelioid cells arranged in cords, nests, and trabeculae within a prominent desmoplastic stroma. All tumors exhibited a consistent immunophenotype: CK5/6+/GATA3+/calponin+/EMA+/DOG1 (perinuclear dot-like staining)/p63-. High-throughput chromosome conformation capture (Hi-C) analysis showed the structural variation of NFATC2::NUTM2E in all 6 cases, whereas RNA sequencing detected the fusion transcripts in 5 cases ( NFATC2::NUTM2A , n=2; NFATC2::NUTM2E , n=3). Ultrastructural examination of 1 case suggested epithelial differentiation. All patients remained disease-free after complete resection (median follow-up: 24 mo; range: 9 to 41 mo). These findings define a novel primary pulmonary tumor entity driven by NFATC2::NUTM2 fusions, and characterized by a distinctive immunophenotype, expanding the spectrum of NUTM2 -associated neoplasms. Our study underscores the utility of multiomics approaches for characterizing rare neoplasms and provides a diagnostic framework for this entity.
PMID:41821426 | DOI:10.1097/PAS.0000000000002533
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Omics In Lung
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NFATC2::NUTM2 Fusion Defines a Novel Primary Pulmonary Epithelial Tumor With a Distinctive Immunophenotype
Am J Surg Pathol. 2026 Mar 13. doi: 10.1097/PAS.0000000000002533. Online ahead of print.ABSTRACTWith the application of molecular techniques in pathologic diagnosis, several novel primary pulmonary epithelial tumors have been continuously discovered and classified under the WHO classification of thoracic tumors. Recently, a pulmonary tumor with NFATC2::NUTM2B fusion was first documented, but the spectrum of NFATC2::NUTM2 fusion variants and their associated pathologic features remains incomplete
NFATC2::NUTM2 Fusion Defines a Novel Primary Pulmonary Epithelial Tumor With a Distinctive Immunophenotype
Am J Surg Pathol. 2026 Mar 13. doi: 10.1097/PAS.0000000000002533. Online ahead of print.
ABSTRACT
With the application of molecular techniques in pathologic diagnosis, several novel primary pulmonary epithelial tumors have been continuously discovered and classified under the WHO classification of thoracic tumors. Recently, a pulmonary tumor with NFATC2::NUTM2B fusion was first documented, but the spectrum of NFATC2::NUTM2 fusion variants and their associated pathologic features remains incompletely characterized. Coincidentally, we also found and described 6 primary pulmonary tumors harboring recurrent NFATC2::NUTM2A/E fusions through integrated genomic analysis. These patients, including 4 females and 2 males, with a median age of 53 years, presented with incidentally detected peripheral lung nodules composed of monotonous epithelioid cells arranged in cords, nests, and trabeculae within a prominent desmoplastic stroma. All tumors exhibited a consistent immunophenotype: CK5/6+/GATA3+/calponin+/EMA+/DOG1 (perinuclear dot-like staining)/p63-. High-throughput chromosome conformation capture (Hi-C) analysis showed the structural variation of NFATC2::NUTM2E in all 6 cases, whereas RNA sequencing detected the fusion transcripts in 5 cases (NFATC2::NUTM2A, n=2; NFATC2::NUTM2E, n=3). Ultrastructural examination of 1 case suggested epithelial differentiation. All patients remained disease-free after complete resection (median follow-up: 24 mo; range: 9 to 41 mo). These findings define a novel primary pulmonary tumor entity driven by NFATC2::NUTM2 fusions, and characterized by a distinctive immunophenotype, expanding the spectrum of NUTM2-associated neoplasms. Our study underscores the utility of multiomics approaches for characterizing rare neoplasms and provides a diagnostic framework for this entity.
PMID:41821426 | DOI:10.1097/PAS.0000000000002533
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Journal of Medical Internet Research
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eHealth Literacy and Type 2 Diabetes Prevention Among At-Risk Populations: Mechanistic Systematic Review Using Theory-Driven Thematic Analysis
Background: Type 2 diabetes (T2D) is emerging as a growing global public health crisis. Early and effective interventions can reduce T2D incidence among at-risk populations. Compared with traditional approaches, digital health technologies offer promising opportunities for prevention, with eHealth literacy (eHL) emerging as a critical determinant of digital prevention outcomes. Objective: This systematic review aims to synthesize and explain the pathways and mechanisms through which eHL supports
eHealth Literacy and Type 2 Diabetes Prevention Among At-Risk Populations: Mechanistic Systematic Review Using Theory-Driven Thematic Analysis
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cs.AI, q-bio.NC updates on arXiv.org
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Multi-Agent DRL for V2X Resource Allocation: Disentangling Challenges and Benchmarking Solutions
arXiv:2603.06607v1 Announce Type: cross Abstract: Multi-agent deep reinforcement learning (DRL) has emerged as a promising approach for radio resource allocation (RRA) in cellular vehicle-to-everything (C-V2X) networks. However, the multifaceted challenges inherent to multi-agent reinforcement learning (MARL) - including non-stationarity, coordination difficulty, large action spaces, partial observability, and limited robustness and generalization - are often intertwined, making it difficult to
Multi-Agent DRL for V2X Resource Allocation: Disentangling Challenges and Benchmarking Solutions
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cs.AI, q-bio.NC updates on arXiv.org
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\$OneMillion-Bench: How Far are Language Agents from Human Experts?
arXiv:2603.07980v1 Announce Type: cross Abstract: As language models (LMs) evolve from chat assistants to long-horizon agents capable of multi-step reasoning and tool use, existing benchmarks remain largely confined to structured or exam-style tasks that fall short of real-world professional demands. To this end, we introduce \$OneMillion-Bench \$OneMillion-Bench, a benchmark of 400 expert-curated tasks spanning Law, Finance, Industry, Healthcare, and Natural Science, built to evaluate agents a
\$OneMillion-Bench: How Far are Language Agents from Human Experts?
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cs.AI, q-bio.NC updates on arXiv.org
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Solution to the 10th ABAW Expression Recognition Challenge: A Robust Multimodal Framework with Safe Cross-Attention and Modality Dropout
arXiv:2603.08034v1 Announce Type: cross Abstract: Emotion recognition in real-world environments is hindered by partial occlusions, missing modalities, and severe class imbalance. To address these issues, particularly for the Affective Behavior Analysis in-the-wild (ABAW) Expression challenge, we propose a multimodal framework that dynamically fuses visual and audio representations. Our approach uses a dual-branch Transformer architecture featuring a safe cross-attention mechanism and a modalit
Solution to the 10th ABAW Expression Recognition Challenge: A Robust Multimodal Framework with Safe Cross-Attention and Modality Dropout
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cs.AI, q-bio.NC updates on arXiv.org
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OCN: Effectively Utilizing Higher-Order Common Neighbors for Better Link Prediction
arXiv:2505.19719v2 Announce Type: replace-cross Abstract: Common Neighbors (CNs) and their higher-order variants are important pairwise features widely used in state-of-the-art link prediction methods. However, existing methods often struggle with the repetition across different orders of CNs and fail to fully leverage their potential. We identify that these limitations stem from two key issues: redundancy and over-smoothing in high-order common neighbors. To address these challenges, we design
OCN: Effectively Utilizing Higher-Order Common Neighbors for Better Link Prediction
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cs.AI, q-bio.NC updates on arXiv.org
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TIGeR: Tool-Integrated Geometric Reasoning in Vision-Language Models for Robotics
arXiv:2510.07181v3 Announce Type: replace-cross Abstract: Vision-Language Models (VLMs) have shown remarkable capabilities in spatial reasoning, yet they remain fundamentally limited to qualitative precision and lack the computational precision required for real-world robotics. Current approaches fail to leverage metric cues from depth sensors and camera calibration, instead reducing geometric problems to pattern recognition tasks that cannot deliver the centimeter-level accuracy essential for
TIGeR: Tool-Integrated Geometric Reasoning in Vision-Language Models for Robotics
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cs.AI, q-bio.NC updates on arXiv.org
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Geometry-Guided Reinforcement Learning for Multi-view Consistent 3D Scene Editing
arXiv:2603.03143v1 Announce Type: cross Abstract: Leveraging the priors of 2D diffusion models for 3D editing has emerged as a promising paradigm. However, maintaining multi-view consistency in edited results remains challenging, and the extreme scarcity of 3D-consistent editing paired data renders supervised fine-tuning (SFT), the most effective training strategy for editing tasks, infeasible. In this paper, we observe that, while generating multi-view consistent 3D content is highly challengi
Geometry-Guided Reinforcement Learning for Multi-view Consistent 3D Scene Editing
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cs.AI, q-bio.NC updates on arXiv.org
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Learning Contextual Runtime Monitors for Safe AI-Based Autonomy
arXiv:2601.20666v2 Announce Type: replace-cross Abstract: We introduce a novel framework for learning context-aware runtime monitors for AI-based control ensembles. Machine-learning (ML) controllers are increasingly deployed in (autonomous) cyber-physical systems because of their ability to solve complex decision-making tasks. However, their accuracy can degrade sharply in unfamiliar environments, creating significant safety concerns. Traditional ensemble methods aim to improve robustness by av
Learning Contextual Runtime Monitors for Safe AI-Based Autonomy
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cs.AI, q-bio.NC updates on arXiv.org
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Recurrent Structural Policy Gradient for Partially Observable Mean Field Games
arXiv:2602.20141v1 Announce Type: new Abstract: Mean Field Games (MFGs) provide a principled framework for modeling interactions in large population models: at scale, population dynamics become deterministic, with uncertainty entering only through aggregate shocks, or common noise. However, algorithmic progress has been limited since model-free methods are too high variance and exact methods scale poorly. Recent Hybrid Structural Methods (HSMs) use Monte Carlo rollouts for the common noise in c
Recurrent Structural Policy Gradient for Partially Observable Mean Field Games
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cs.AI, q-bio.NC updates on arXiv.org
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Look Back to Reason Forward: Revisitable Memory for Long-Context LLM Agents
arXiv:2509.23040v4 Announce Type: replace-cross Abstract: Large language models face challenges in long-context question answering, where key evidence of a query may be dispersed across millions of tokens. Existing works equip large language models with a memory buffer that is dynamically updated via a linear document scan, also known as the "memorize while reading" methods. While this approach scales efficiently, it suffers from pruning of latent evidence, information loss through overwriting,
Look Back to Reason Forward: Revisitable Memory for Long-Context LLM Agents
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cs.AI, q-bio.NC updates on arXiv.org
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Step 3.5 Flash: Open Frontier-Level Intelligence with 11B Active Parameters
arXiv:2602.10604v2 Announce Type: replace-cross Abstract: We introduce Step 3.5 Flash, a sparse Mixture-of-Experts (MoE) model that bridges frontier-level agentic intelligence and computational efficiency. We focus on what matters most when building agents: sharp reasoning and fast, reliable execution. Step 3.5 Flash pairs a 196B-parameter foundation with 11B active parameters for efficient inference. It is optimized with interleaved 3:1 sliding-window/full attention and Multi-Token Prediction
Step 3.5 Flash: Open Frontier-Level Intelligence with 11B Active Parameters
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cs.AI, q-bio.NC updates on arXiv.org
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ST-EVO: Towards Generative Spatio-Temporal Evolution of Multi-Agent Communication Topologies
arXiv:2602.14681v2 Announce Type: replace-cross Abstract: LLM-powered Multi-Agent Systems (MAS) have emerged as an effective approach towards collaborative intelligence, and have attracted wide research interests. Among them, ``self-evolving'' MAS, treated as a more flexible and powerful technical route, can construct task-adaptive workflows or communication topologies, instead of relying on a predefined static structue template. Current self-evolving MAS mainly focus on Spatial Evolving or Tem