Normal view
-
cs.AI, q-bio.NC updates on arXiv.org
-
Scaling Attention via Feature Sparsity
arXiv:2603.22300v1 Announce Type: cross Abstract: Scaling Transformers to ultra-long contexts is bottlenecked by the $O(n^2 d)$ cost of self-attention. Existing methods reduce this cost along the sequence axis through local windows, kernel approximations, or token-level sparsity, but these approaches consistently degrade accuracy. In this paper, we instead explore an orthogonal axis: feature sparsity. We propose Sparse Feature Attention (SFA), where queries and keys are represented as $k$-spars
-
cs.AI, q-bio.NC updates on arXiv.org
-
PhotoAgent: A Robotic Photographer with Spatial and Aesthetic Understanding
arXiv:2603.22796v1 Announce Type: cross Abstract: Embodied agents for creative tasks like photography must bridge the semantic gap between high-level language commands and geometric control. We introduce PhotoAgent, an agent that achieves this by integrating Large Multimodal Models (LMMs) reasoning with a novel control paradigm. PhotoAgent first translates subjective aesthetic goals into solvable geometric constraints via LMM-driven, chain-of-thought (CoT) reasoning, allowing an analytical solv
PhotoAgent: A Robotic Photographer with Spatial and Aesthetic Understanding
-
Omics In Lung
-
Low-dose intestinal irradiation enhances the efficacy and prognosis of PD-1 blockade in metastatic non-small cell lung cancer
Clin Cancer Res. 2026 Mar 18. doi: 10.1158/1078-0432.CCR-25-4153. Online ahead of print.ABSTRACTPURPOSE: Intestinal low-dose irradiation (ILDR) may enhance immunotherapy efficacy by modulating the gut microbiota and metabolism; however, its role in metastatic non-small cell lung cancer (mNSCLC), particularly in the first-line setting, remains unclear.EXPERIMENTAL DESIGN: This multicenter retrospective and prospective study included mNSCLC patients receiving first- and second-line programmed cell
Low-dose intestinal irradiation enhances the efficacy and prognosis of PD-1 blockade in metastatic non-small cell lung cancer
Clin Cancer Res. 2026 Mar 18. doi: 10.1158/1078-0432.CCR-25-4153. Online ahead of print.
ABSTRACT
PURPOSE: Intestinal low-dose irradiation (ILDR) may enhance immunotherapy efficacy by modulating the gut microbiota and metabolism; however, its role in metastatic non-small cell lung cancer (mNSCLC), particularly in the first-line setting, remains unclear.
EXPERIMENTAL DESIGN: This multicenter retrospective and prospective study included mNSCLC patients receiving first- and second-line programmed cell death protein 1 (PD-1) inhibitors along with abdominopelvic radiotherapy between 2018 and 2025. Patients were stratified by the mean intestinal radiation dose into <1 Gy, 1-3 Gy, and >3 Gy groups and treatment outcomes were compared. The blood and fecal samples were subjected to multi-omics profiling.
RESULTS: g>309 patients were included in the retrospective analysis. Optimal efficacy was observed with a small intestinal mean radiation dose (SIMRD) of 1-3 Gy, showing longer progression-free survival (PFS, 10.2 months) and overall survival (OS, 22.8 months) (P < 0.01), which was consistent across subgroups. Compared with 1-3 Gy, SIMRD >3 Gy (Hazard ratio [HR] = 4.87, P < 0.001) and <1 Gy (HR = 1.85, P < 0.001) independently predicted worse OS. Prospective results confirmed the best disease control rate (P = 0.041) and PFS (P = 0.046) with SIMRD of 1-3 Gy. Responders were enriched in Bacillota, Clostridia, and indole derivatives, particularly indole-3-carboxylic acid. Moreover, the 1-3 Gy group exhibited increased circulating macrophage inflammatory protein-3α and reduced circulating α4β7+ regulatory T cells.
CONCLUSIONS: ILDR influences the efficacy of PD-1 blockade in patients with mNSCLC, particularly when SIMRD is maintained within the 1-3 Gy range, likely through modulation of the gut microbiota-metabolite-immune axis.
PMID:41849236 | DOI:10.1158/1078-0432.CCR-25-4153
-
cs.AI, q-bio.NC updates on arXiv.org
-
SkillsBench: Benchmarking How Well Agent Skills Work Across Diverse Tasks
arXiv:2602.12670v3 Announce Type: replace Abstract: Agent Skills are structured packages of procedural knowledge that augment LLM agents at inference time. Despite rapid adoption, there is no standard way to measure whether they actually help. We present SkillsBench, a benchmark of 86 tasks across 11 domains paired with curated Skills and deterministic verifiers. Each task is evaluated under three conditions: no Skills, curated Skills, and self-generated Skills. We test 7 agent-model configurat
SkillsBench: Benchmarking How Well Agent Skills Work Across Diverse Tasks
-
cs.AI, q-bio.NC updates on arXiv.org
-
SkillsBench: Benchmarking How Well Agent Skills Work Across Diverse Tasks
arXiv:2602.12670v2 Announce Type: replace Abstract: Agent Skills are structured packages of procedural knowledge that augment LLM agents at inference time. Despite rapid adoption, there is no standard way to measure whether they actually help. We present SkillsBench, a benchmark of 86 tasks across 11 domains paired with curated Skills and deterministic verifiers. Each task is evaluated under three conditions: no Skills, curated Skills, and self-generated Skills. We test 7 agent-model configurat
SkillsBench: Benchmarking How Well Agent Skills Work Across Diverse Tasks
-
Cell Death Discovery nature.com science feeds
-
Lysophosphatidylcholine acyltransferase 1 promotes head and neck squamous cell carcinoma progression by enhancing COX17-dependent oxidative phosphorylation
Cell Death Discovery, Published online: 06 March 2026; doi:10.1038/s41420-026-02994-3Lysophosphatidylcholine acyltransferase 1 promotes head and neck squamous cell carcinoma progression by enhancing COX17-dependent oxidative phosphorylation
Lysophosphatidylcholine acyltransferase 1 promotes head and neck squamous cell carcinoma progression by enhancing COX17-dependent oxidative phosphorylation
Cell Death Discovery, Published online: 06 March 2026; doi:10.1038/s41420-026-02994-3
Lysophosphatidylcholine acyltransferase 1 promotes head and neck squamous cell carcinoma progression by enhancing COX17-dependent oxidative phosphorylation-
cs.AI, q-bio.NC updates on arXiv.org
-
Kaiwu-PyTorch-Plugin: Bridging Deep Learning and Photonic Quantum Computing for Energy-Based Models and Active Sample Selection
arXiv:2602.19114v1 Announce Type: cross Abstract: This paper introduces the Kaiwu-PyTorch-Plugin (KPP) to bridge Deep Learning and Photonic Quantum Computing across multiple dimensions. KPP integrates the Coherent Ising Machine into the PyTorch ecosystem, addressing classical inefficiencies in Energy-Based Models. The framework facilitates quantum integration in three key aspects: accelerating Boltzmann sampling, optimizing training data via Active Sampling, and constructing hybrid architecture
Kaiwu-PyTorch-Plugin: Bridging Deep Learning and Photonic Quantum Computing for Energy-Based Models and Active Sample Selection
-
cs.AI, q-bio.NC updates on arXiv.org
-
KVCache Cache in the Wild: Characterizing and Optimizing KVCache Cache at a Large Cloud Provider
arXiv:2506.02634v5 Announce Type: replace-cross Abstract: Serving large language models (LLMs) is important for cloud providers, and caching intermediate results (KV\$) after processing each request substantially improves serving throughput and latency. However, there is limited understanding of how LLM serving benefits from KV\$ caching, where system design decisions like cache eviction policies are highly workload-dependent. In this paper, we present the first systematic characterization of t