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LiteInception: A Lightweight and Interpretable Deep Learning Framework for General Aviation Fault Diagnosis

arXiv:2604.01725v1 Announce Type: new Abstract: General aviation fault diagnosis and efficient maintenance are critical to flight safety; however, deploying deep learning models on resource-constrained edge devices poses dual challenges in computational capacity and interpretability. This paper proposes LiteInception--a lightweight interpretable fault diagnosis framework designed for edge deployment. The framework adopts a two-stage cascaded architecture aligned with standard maintenance workflows: Stage 1 performs high-recall fault detection, and Stage 2 conducts fine-grained fault classification on anomalous samples, thereby decoupling optimization objectives and enabling on-demand allocation of computational resources. For model compression, a multi-method fusion strategy based on mutual information, gradient analysis, and SE attention weights is proposed to reduce the input sensor channels from 23 to 15, and a 1+1 branch LiteInception architecture is introduced that compresses InceptionTime parameters by 70%, accelerates CPU inference by over 8x, with less than 3% F1 loss. Furthermore, knowledge distillation is introduced as a precision-recall regulation mechanism, enabling the same lightweight model to adapt to different scenarios--such as safety-critical and auxiliary diagnosis--by switching training strategies. Finally, a dual-layer interpretability framework integrating four attribution methods is constructed, providing traceable evidence chains of "which sensor x which time period." Experiments on the NGAFID dataset demonstrate a fault detection accuracy of 81.92% with 83.24% recall, and a fault identification accuracy of 77.00%, validating the framework's favorable balance among efficiency, accuracy, and interpretability.

Tex3D: Objects as Attack Surfaces via Adversarial 3D Textures for Vision-Language-Action Models

arXiv:2604.01618v1 Announce Type: cross Abstract: Vision-language-action (VLA) models have shown strong performance in robotic manipulation, yet their robustness to physically realizable adversarial attacks remains underexplored. Existing studies reveal vulnerabilities through language perturbations and 2D visual attacks, but these attack surfaces are either less representative of real deployment or limited in physical realism. In contrast, adversarial 3D textures pose a more physically plausible and damaging threat, as they are naturally attached to manipulated objects and are easier to deploy in physical environments. Bringing adversarial 3D textures to VLA systems is nevertheless nontrivial. A central obstacle is that standard 3D simulators do not provide a differentiable optimization path from the VLA objective function back to object appearance, making it difficult to optimize through an end-to-end manner. To address this, we introduce Foreground-Background Decoupling (FBD), which enables differentiable texture optimization through dual-renderer alignment while preserving the original simulation environment. To further ensure that the attack remains effective across long-horizon and diverse viewpoints in the physical world, we propose Trajectory-Aware Adversarial Optimization (TAAO), which prioritizes behaviorally critical frames and stabilizes optimization with a vertex-based parameterization. Built on these designs, we present Tex3D, the first framework for end-to-end optimization of 3D adversarial textures directly within the VLA simulation environment. Experiments in both simulation and real-robot settings show that Tex3D significantly degrades VLA performance across multiple manipulation tasks, achieving task failure rates of up to 96.7\%. Our empirical results expose critical vulnerabilities of VLA systems to physically grounded 3D adversarial attacks and highlight the need for robustness-aware training.

InCoder-32B: Code Foundation Model for Industrial Scenarios

arXiv:2603.16790v3 Announce Type: replace-cross Abstract: Recent code large language models have achieved remarkable progress on general programming tasks. Nevertheless, their performance degrades significantly in industrial scenarios that require reasoning about hardware semantics, specialized language constructs, and strict resource constraints. To address these challenges, we introduce InCoder-32B (Industrial-Coder-32B), the first 32B-parameter code foundation model unifying code intelligence across chip design, GPU kernel optimization, embedded systems, compiler optimization, and 3D modeling. By adopting an efficient architecture, we train InCoder-32B from scratch with general code pre-training, curated industrial code annealing, mid-training that progressively extends context from 8K to 128K tokens with synthetic industrial reasoning data, and post-training with execution-grounded verification. We conduct extensive evaluation on 14 mainstream general code benchmarks and 9 industrial benchmarks spanning 4 specialized domains. Results show InCoder-32B achieves highly competitive performance on general tasks while establishing strong open-source baselines across industrial domains.

Single-cell multiomics uncovers an endothelial mechanosensitive PIEZO1-IL-33 axis driving pulmonary fibrosis

Nat Commun. 2026 Mar 20;17(1):2655. doi: 10.1038/s41467-026-70193-w.

ABSTRACT

Pulmonary fibrosis represents a progressive interstitial lung disease marked by excessive extracellular matrix deposition and architectural distortion. Vascular endothelial cells critically contribute to fibrogenesis through paracrine secretion of pro-fibrotic mediators, yet their mechanobiological regulation remains elusive. Using integrated single-cell multi-omics profiling of human pulmonary fibrosis specimens and experimental fibrosis models induced by bleomycin or silica, we identify mechanosensitive Piezo1 upregulation in Endothelial cells as a hallmark of fibrotic progression. Endothelial-specific Piezo1 knockout significantly attenuates Bleomycin-induced fibrotic remodeling in male mice, establishing its pathogenic necessity. Mechanistically, PIEZO1 activation promotes pulmonary fibrosis development via CAPN2-mediated STAT3 phosphorylation, which may regulate the secretion of the pro-fibrotic molecule interleukin-33. These findings suggest that the endothelial PIEZO1-CAPN2-STAT3-IL33 axis is a potential therapeutic target for PF intervention.

PMID:41862476 | PMC:PMC13004862 | DOI:10.1038/s41467-026-70193-w

Trem1 regulates neutrophil metabolism and recruitment in lung ischemia-reperfusion injury

Redox Biol. 2026 Jan 14;92:104026. doi: 10.1016/j.redox.2026.104026. Online ahead of print.

ABSTRACT

Primary graft dysfunction (PGD) caused by ischemia-reperfusion injury (IRI) is a major complication after lung transplantation, yet its underlying mechanisms remain unclear. Triggering receptor expressed on myeloid cells 1 (Trem1) is an important mediator of inflammation, but its role in neutrophil function and metabolic reprogramming during lung IRI is not well understood. In this study, we used a murine orthotopic lung transplantation model with cold ischemia and reperfusion, and Trem1 knockout (Trem1-/-) and myeloid-specific Trem1 conditional knockout mice (LysmCreTrem1fl) to explore the role of Trem1 in neutrophil recruitment, neutrophil extracellular trap (NET) formation, and metabolism. Our results show that Trem1 expression increases in both mouse and human lungs after reperfusion and correlates with neutrophil infiltration and lung injury. Trem1 deficiency significantly reduced neutrophil and macrophage recruitment, NET formation, and tissue damage. Multi-omics analysis revealed that Trem1 deletion suppressed oxidative phosphorylation (OXPHOS) and induced a metabolic shift in neutrophils toward glycolysis. In clinical samples, the abundance of TREM1+ neutrophils was correlated with PGD severity and OXPHOS activity. These findings identify Trem1 as a key regulator of neutrophil metabolism and recruitment in lung IRI, and suggest that targeting Trem1 may provide a novel therapeutic strategy to mitigate PGD and improve lung transplant outcomes.

PMID:41861599 | DOI:10.1016/j.redox.2026.104026

DSH-Bench: A Difficulty- and Scenario-Aware Benchmark with Hierarchical Subject Taxonomy for Subject-Driven Text-to-Image Generation

arXiv:2603.08090v1 Announce Type: cross Abstract: Significant progress has been achieved in subject-driven text-to-image (T2I) generation, which aims to synthesize new images depicting target subjects according to user instructions. However, evaluating these models remains a significant challenge. Existing benchmarks exhibit critical limitations: 1) insufficient diversity and comprehensiveness in subject images, 2) inadequate granularity in assessing model performance across different subject difficulty levels and prompt scenarios, and 3) a profound lack of actionable insights and diagnostic guidance for subsequent model refinement. To address these limitations, we propose DSH-Bench, a comprehensive benchmark that enables systematic multi-perspective analysis of subject-driven T2I models through four principal innovations: 1) a hierarchical taxonomy sampling mechanism ensuring comprehensive subject representation across 58 fine-grained categories, 2) an innovative classification scheme categorizing both subject difficulty level and prompt scenario for granular capability assessment, 3) a novel Subject Identity Consistency Score (SICS) metric demonstrating a 9.4\% higher correlation with human evaluation compared to existing measures in quantifying subject preservation, and 4) a comprehensive set of diagnostic insights derived from the benchmark, offering critical guidance for optimizing future model training paradigms and data construction strategies. Through an extensive empirical evaluation of 19 leading models, DSH-Bench uncovers previously obscured limitations in current approaches, establishing concrete directions for future research and development.

City Editing: Hierarchical Agentic Execution for Dependency-Aware Urban Geospatial Modification

arXiv:2602.19326v1 Announce Type: cross Abstract: As cities evolve over time, challenges such as traffic congestion and functional imbalance increasingly necessitate urban renewal through efficient modification of existing plans, rather than complete re-planning. In practice, even minor urban changes require substantial manual effort to redraw geospatial layouts, slowing the iterative planning and decision-making procedure. Motivated by recent advances in agentic systems and multimodal reasoning, we formulate urban renewal as a machine-executable task that iteratively modifies existing urban plans represented in structured geospatial formats. More specifically, we represent urban layouts using GeoJSON and decompose natural-language editing instructions into hierarchical geometric intents spanning polygon-, line-, and point-level operations. To coordinate interdependent edits across spatial elements and abstraction levels, we propose a hierarchical agentic framework that jointly performs multi-level planning and execution with explicit propagation of intermediate spatial constraints. We further introduce an iterative execution-validation mechanism that mitigates error accumulation and enforces global spatial consistency during multi-step editing. Extensive experiments across diverse urban editing scenarios demonstrate significant improvements in efficiency, robustness, correctness, and spatial validity over existing baselines.

Cautious Optimizers: Improving Training with One Line of Code

arXiv:2411.16085v4 Announce Type: replace-cross Abstract: AdamW has been the default optimizer for transformer pretraining. For many years, our community searched for faster and more stable optimizers with only constrained positive outcomes. In this work, we propose a \textbf{one-line modification in Pytorch} to any momentum-based optimizer, which we rename cautious optimizer, e.g. C-AdamW and C-Lion. Our theoretical result shows that this modification preserves Adam's Hamiltonian function and it does not break the convergence guarantee under the Lyapunov analysis. In addition, a whole new family of optimizers is revealed by our theoretical insight. Among them, we pick the simplest one for empirical experiments, showing not only consistent speed-up on LLM pretraining, but also image classification, with minimum extra tuning on hyperparameters. Code is available at https://github.com/kyleliang919/C-Optim.

IntentMiner: Intent Inversion Attack via Tool Call Analysis in the Model Context Protocol

arXiv:2512.14166v2 Announce Type: replace-cross Abstract: The evolution of Large Language Models (LLMs) into Agentic AI has established the Model Context Protocol (MCP) as the standard for connecting reasoning engines with external tools. Although this decoupled architecture fosters modularity, it simultaneously shatters the traditional trust boundary. We uncover a novel privacy vector inherent to this paradigm: the Intent Inversion Attack. We show that semi-honest third-party MCP servers can accurately reconstruct users' underlying intents by leveraging only authorized metadata (e.g., function signatures, arguments, and receipts), effectively bypassing the need for raw query access. To quantify this threat, we introduce IntentMiner. Unlike statistical approaches, IntentMiner employs a hierarchical semantic parsing strategy that performs step-level intent reconstruction by analyzing tool functions, parameter entities, and result feedback in an orthogonal manner. Experiments on the ToolACE benchmark reveal that IntentMiner achieves a semantic alignment of over 85% with original queries, substantially surpassing LLM baselines. This work exposes a critical endogenous vulnerability: without semantic obfuscation, executing functions requires the transparency of intent, thereby challenging the privacy foundations of next-generation AI agents.
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