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cs.AI, q-bio.NC updates on arXiv.org
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Scale over Preference: The Impact of AI-Generated Content on Online Content Ecology
arXiv:2604.01690v1 Announce Type: new Abstract: The rapid proliferation of Artificial Intelligence-Generated Content (AIGC) is fundamentally restructuring online content ecologies, necessitating a rigorous examination of its behavioral and distributional implications. Leveraging a comprehensive longitudinal dataset comprising tens of millions of users from a leading Chinese video-sharing platform, this study elucidated the distinct creation and consumption behaviors characterizing AIGC versus H
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cs.AI, q-bio.NC updates on arXiv.org
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Unifying Group-Relative and Self-Distillation Policy Optimization via Sample Routing
arXiv:2604.02288v1 Announce Type: cross Abstract: Reinforcement learning with verifiable rewards (RLVR) has become a standard paradigm for post-training large language models. While Group Relative Policy Optimization (GRPO) is widely adopted, its coarse credit assignment uniformly penalizes failed rollouts, lacking the token-level focus needed to efficiently address specific deviations. Self-Distillation Policy Optimization (SDPO) addresses this by providing denser, more targeted logit-level su
Unifying Group-Relative and Self-Distillation Policy Optimization via Sample Routing
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cs.AI, q-bio.NC updates on arXiv.org
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Beyond Preset Identities: How Agents Form Stances and Boundaries in Generative Societies
arXiv:2603.23406v2 Announce Type: replace Abstract: While large language models simulate social behaviors, their capacity for stable stance formation and identity negotiation during complex interventions remains unclear. To overcome the limitations of static evaluations, this paper proposes a novel mixed-methods framework combining computational virtual ethnography with quantitative socio-cognitive profiling. By embedding human researchers into generative multiagent communities, controlled disc
Beyond Preset Identities: How Agents Form Stances and Boundaries in Generative Societies
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Omics In Lung
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Pathogenesis and immune regulation of rheumatoid arthritis-associated interstitial lung disease: from basic research to clinical implications
Front Immunol. 2026 Mar 13;17:1770348. doi: 10.3389/fimmu.2026.1770348. eCollection 2026.ABSTRACTInterstitial lung disease (ILD) is one of the most common extra-articular manifestations of rheumatoid arthritis (RA). Some patients with RA-ILD may develop progressive pulmonary fibrosis, leading to severe impairment of lung function and respiratory failure, which impacts quality of life and can even be life-threatening. This review identified genetic susceptibility, environmental factors, and immun
Pathogenesis and immune regulation of rheumatoid arthritis-associated interstitial lung disease: from basic research to clinical implications
Front Immunol. 2026 Mar 13;17:1770348. doi: 10.3389/fimmu.2026.1770348. eCollection 2026.
ABSTRACT
Interstitial lung disease (ILD) is one of the most common extra-articular manifestations of rheumatoid arthritis (RA). Some patients with RA-ILD may develop progressive pulmonary fibrosis, leading to severe impairment of lung function and respiratory failure, which impacts quality of life and can even be life-threatening. This review identified genetic susceptibility, environmental factors, and immune dysregulation as key contributors to the etiology and pathogenesis of RA-ILD. We highlight that autoantibodies, adaptive immune abnormalities, and tertiary lymphoid organ formation significantly drive pulmonary inflammation and fibrosis, while pro-inflammatory cytokines and epithelial-mesenchymal transition (EMT) further contribute to lung tissue injury. Current treatment options, including glucocorticoids, immunosuppressants, and antifibrotic agents such as nintedanib and pirfenidone, are often limited by substantial side effects. Additionally, emerging therapies like JAK inhibitors, CAR-T cells, and the upcoming phosphodiesterase-4B inhibitor, nerandomilast, show promise, but no curative treatment exists to date. Future research could focus on multi-omics technologies and conducting multicenter clinical trials to establish therapeutic targets and advance precision medicine for RA-ILD.
PMID:41909710 | PMC:PMC13021622 | DOI:10.3389/fimmu.2026.1770348
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cs.AI, q-bio.NC updates on arXiv.org
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Beyond Preset Identities: How Agents Form Stances and Boundaries in Generative Societies
arXiv:2603.23406v1 Announce Type: new Abstract: While large language models simulate social behaviors, their capacity for stable stance formation and identity negotiation during complex interventions remains unclear. To overcome the limitations of static evaluations, this paper proposes a novel mixed-methods framework combining computational virtual ethnography with quantitative socio-cognitive profiling. By embedding human researchers into generative multiagent communities, controlled discursi
Beyond Preset Identities: How Agents Form Stances and Boundaries in Generative Societies
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cs.AI, q-bio.NC updates on arXiv.org
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ForestPrune: High-ratio Visual Token Compression for Video Multimodal Large Language Models via Spatial-Temporal Forest Modeling
arXiv:2603.22911v1 Announce Type: cross Abstract: Due to the great saving of computation and memory overhead, token compression has become a research hot-spot for MLLMs and achieved remarkable progress in image-language tasks. However, for the video, existing methods still fall short of high-ratio token compression. We attribute this shortcoming to the insufficient modeling of temporal and continual video content, and propose a novel and training-free token pruning method for video MLLMs, terme
ForestPrune: High-ratio Visual Token Compression for Video Multimodal Large Language Models via Spatial-Temporal Forest Modeling
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Nature Biotechnology - Issue - nature.com science feeds
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Sustained nitric oxide production by engineered <i>E. coli</i> remodels the tumor microenvironment and potentiates immunotherapy
Nature Biotechnology, Published online: 18 March 2026; doi:10.1038/s41587-026-03054-ySolid tumors are sensitized to anti‑PD‑L1 immunotherapy by engineered E. coli to produce nitric oxide.
Sustained nitric oxide production by engineered <i>E. coli</i> remodels the tumor microenvironment and potentiates immunotherapy
Nature Biotechnology, Published online: 18 March 2026; doi:10.1038/s41587-026-03054-y
Solid tumors are sensitized to anti‑PD‑L1 immunotherapy by engineered E. coli to produce nitric oxide.-
cs.AI, q-bio.NC updates on arXiv.org
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Adaptation of Agentic AI: A Survey of Post-Training, Memory, and Skills
arXiv:2512.16301v3 Announce Type: replace Abstract: Large language model (LLM) agents are moving beyond prompting alone. ChatGPT marked the rise of general-purpose LLM assistants, DeepSeek showed that on-policy reinforcement learning with verifiable rewards can improve reasoning and tool use, and OpenClaw highlights a newer direction in which agents accumulate persistent memory and reusable skills. Yet the research landscape remains fragmented across post-training, retrieval, memory, and skill
Adaptation of Agentic AI: A Survey of Post-Training, Memory, and Skills
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cs.AI, q-bio.NC updates on arXiv.org
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FOCA: Frequency-Oriented Cross-Domain Forgery Detection, Localization and Explanation via Multi-Modal Large Language Model
arXiv:2602.18880v1 Announce Type: cross Abstract: Advances in image tampering techniques, particularly generative models, pose significant challenges to media verification, digital forensics, and public trust. Existing image forgery detection and localization (IFDL) methods suffer from two key limitations: over-reliance on semantic content while neglecting textural cues, and limited interpretability of subtle low-level tampering traces. To address these issues, we propose FOCA, a multimodal lar
FOCA: Frequency-Oriented Cross-Domain Forgery Detection, Localization and Explanation via Multi-Modal Large Language Model
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cs.AI, q-bio.NC updates on arXiv.org
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Elo-Evolve: A Co-evolutionary Framework for Language Model Alignment
arXiv:2602.13575v1 Announce Type: cross Abstract: Current alignment methods for Large Language Models (LLMs) rely on compressing vast amounts of human preference data into static, absolute reward functions, leading to data scarcity, noise sensitivity, and training instability. We introduce Elo-Evolve, a co-evolutionary framework that redefines alignment as dynamic multi-agent competition within an adaptive opponent pool. Our approach makes two key innovations: (1) eliminating Bradley-Terry mode