Normal view
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cs.AI, q-bio.NC updates on arXiv.org
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MindAlign: Bridging EEG, Vision, and Language for Zero-Shot Visual Decoding
arXiv:2605.24523v1 Announce Type: cross Abstract: Visual decoding from brain signals is a key challenge at the intersection of computer vision and neuroscience, requiring methods that bridge neural representations and computational models of vision. We introduce a tri-modal contrastive framework for EEG-based visual decoding that aligns EEG, visual, and textual representations within a unified latent space. Our approach follows a two-stage design. First, we pre-train an EEG encoder via masked r
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cs.AI, q-bio.NC updates on arXiv.org
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What Are We Actually Decoding? Source Attribution for Non-Invasive Brain-to-Language Retrieval
arXiv:2605.24524v1 Announce Type: cross Abstract: In non-invasive neural language decoding, results can be inflated by sources that are not stimulus-evoked neural evidence: decoder priors, embedding-based metrics, and non-neural structural nuisances such as signal duration. The methodological challenge is therefore attribution: a reported gain is more informative when it can be traced to a specific source. We recast stimulus-locked MEG-to-audio retrieval as an auditing framework that separates
What Are We Actually Decoding? Source Attribution for Non-Invasive Brain-to-Language Retrieval
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(Multiomics OR Omics) AND (Pancreatic)
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Data-driven precision: artificial intelligence redefining immunoradiotherapy in advanced pancreatic cancer
Front Pharmacol. 2026 May 8;17:1804673. doi: 10.3389/fphar.2026.1804673. eCollection 2026.ABSTRACTAdvanced pancreatic ductal adenocarcinoma (PDAC) remains among the most formidable challenges in oncology, driven by a profoundly immunosuppressive tumor microenvironment (TME) and pervasive resistance to systemic and local therapies. Although immune checkpoint inhibitors (ICIs) can synergize with radiotherapy (RT) in several malignancies, the clinical benefit of immunoradiotherapy (iRT) in PDAC has
Data-driven precision: artificial intelligence redefining immunoradiotherapy in advanced pancreatic cancer
Front Pharmacol. 2026 May 8;17:1804673. doi: 10.3389/fphar.2026.1804673. eCollection 2026.
ABSTRACT
Advanced pancreatic ductal adenocarcinoma (PDAC) remains among the most formidable challenges in oncology, driven by a profoundly immunosuppressive tumor microenvironment (TME) and pervasive resistance to systemic and local therapies. Although immune checkpoint inhibitors (ICIs) can synergize with radiotherapy (RT) in several malignancies, the clinical benefit of immunoradiotherapy (iRT) in PDAC has been modest, highlighting the limitations of population-averaged paradigms that fail to capture extensive inter- and intratumoral heterogeneity. Here, we synthesize an artificial intelligence (AI)-enabled framework to refine both the biological rationale and clinical implementation of iRT for advanced PDAC through integrative analysis of multimodal data (clinical variables, imaging, RT dose distributions, and multi-omics). We highlight advances in three domains. First, AI-based deconvolution of TME heterogeneity can delineate clinically relevant molecular subtypes and spatial immune architectures that may be therapeutically tractable. Second, AI-driven modeling can optimize spatiotemporal RT-immunotherapy interactions, informing individualized dose, fractionation, and biologically guided target definition. Third, AI-supported predictive modeling and adaptive feedback can enable response-guided treatment adjustment beyond static planning. We also discuss unresolved clinical questions and key translational barriers, including data scarcity, lack of standardization, and limited interpretability. Finally, we outline priorities for translation-prospective digital biobanks, hybrid mechanistic-data-driven modeling, and adaptive trial designs-to enable rigorous validation and clinical deployment. Collectively, these developments position AI as a catalyst to move iRT for PDAC from empiricism toward real-time, individualized precision medicine.
PMID:42181887 | PMC:PMC13194001 | DOI:10.3389/fphar.2026.1804673
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Oncogenesis - nature.com science feeds
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PRMT6-mediated EZH2 arginine methylation is critical for breast cancer development
Oncogenesis, Published online: 19 April 2026; doi:10.1038/s41389-026-00619-zPRMT6-mediated EZH2 arginine methylation is critical for breast cancer development
PRMT6-mediated EZH2 arginine methylation is critical for breast cancer development
Oncogenesis, Published online: 19 April 2026; doi:10.1038/s41389-026-00619-z
PRMT6-mediated EZH2 arginine methylation is critical for breast cancer development-
cs.AI, q-bio.NC updates on arXiv.org
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Affording Process Auditability with QualAnalyzer: An Atomistic LLM Analysis Tool for Qualitative Research
arXiv:2604.03820v1 Announce Type: new Abstract: Large language models are increasingly used for qualitative data analysis, but many workflows obscure how analytic conclusions are produced. We present QualAnalyzer, an open-source Chrome extension for Google Workspace that supports atomistic LLM analysis by processing each data segment independently and preserving the prompt, input, and output for every unit. Through two case studies -- holistic essay scoring and deductive thematic coding of inte
Affording Process Auditability with QualAnalyzer: An Atomistic LLM Analysis Tool for Qualitative Research
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cs.AI, q-bio.NC updates on arXiv.org
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ReFlow: Self-correction Motion Learning for Dynamic Scene Reconstruction
arXiv:2604.01561v1 Announce Type: cross Abstract: We present ReFlow, a unified framework for monocular dynamic scene reconstruction that learns 3D motion in a novel self-correction manner from raw video. Existing methods often suffer from incomplete scene initialization for dynamic regions, leading to unstable reconstruction and motion estimation, which often resorts to external dense motion guidance such as pre-computed optical flow to further stabilize and constrain the reconstruction of dyna
ReFlow: Self-correction Motion Learning for Dynamic Scene Reconstruction
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cs.AI, q-bio.NC updates on arXiv.org
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TSHA: A Benchmark for Visual Language Models in Trustworthy Safety Hazard Assessment Scenarios
arXiv:2603.29759v1 Announce Type: cross Abstract: Recent advances in vision-language models (VLMs) have accelerated their application to indoor safety hazards assessment. However, existing benchmarks suffer from three fundamental limitations: (1) heavy reliance on synthetic datasets constructed via simulation software, creating a significant domain gap with real-world environments; (2) oversimplified safety tasks with artificial constraints on hazard and scene types, thereby limiting model gene
TSHA: A Benchmark for Visual Language Models in Trustworthy Safety Hazard Assessment Scenarios
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cs.AI, q-bio.NC updates on arXiv.org
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Let the Agent Steer: Closed-Loop Ranking Optimization via Influence Exchange
arXiv:2603.27765v2 Announce Type: replace Abstract: Recommendation ranking is fundamentally an influence allocation problem: a sorting formula distributes ranking influence among competing factors, and the business outcome depends on finding the optimal "exchange rates" among them. However, offline proxy metrics systematically misjudge how influence reallocation translates to online impact, with asymmetric bias across metrics that a single calibration factor cannot correct. We present Sortify
Let the Agent Steer: Closed-Loop Ranking Optimization via Influence Exchange
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Nature - Issue - nature.com science feeds
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Structure of the mouse cytoplasmic lattice
Nature, Published online: 31 March 2026; doi:10.1038/s41586-026-10442-6Structure of the mouse cytoplasmic lattice
Structure of the mouse cytoplasmic lattice
Nature, Published online: 31 March 2026; doi:10.1038/s41586-026-10442-6
Structure of the mouse cytoplasmic lattice-
cs.AI, q-bio.NC updates on arXiv.org
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EVA: Efficient Reinforcement Learning for End-to-End Video Agent
arXiv:2603.22918v1 Announce Type: cross Abstract: Video understanding with multimodal large language models (MLLMs) remains challenging due to the long token sequences of videos, which contain extensive temporal dependencies and redundant frames. Existing approaches typically treat MLLMs as passive recognizers, processing entire videos or uniformly sampled frames without adaptive reasoning. Recent agent-based methods introduce external tools, yet still depend on manually designed workflows and
EVA: Efficient Reinforcement Learning for End-to-End Video Agent
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cs.AI, q-bio.NC updates on arXiv.org
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Motion Dreamer: Boundary Conditional Motion Reasoning for Physically Coherent Video Generation
arXiv:2412.00547v4 Announce Type: replace-cross Abstract: Recent advances in video generation have shown promise for generating future scenarios, critical for planning and control in autonomous driving and embodied intelligence. However, real-world applications demand more than visually plausible predictions; they require reasoning about object motions based on explicitly defined boundary conditions, such as initial scene image and partial object motion. We term this capability Boundary Conditi
Motion Dreamer: Boundary Conditional Motion Reasoning for Physically Coherent Video Generation
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cs.AI, q-bio.NC updates on arXiv.org
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Dynamic Adversarial Reinforcement Learning for Robust Multimodal Large Language Models
arXiv:2602.22227v3 Announce Type: replace-cross Abstract: Despite their impressive capabilities, Multimodal Large Language Models (MLLMs) exhibit perceptual fragility when confronted with visually complex scenes. This weakness stems from a reliance on finite training datasets, which are prohibitively expensive to scale and impose a ceiling on model robustness. We introduce \textbf{AOT-SFT}, a large-scale adversarial dataset for bootstrapping MLLM robustness. Building on this, we propose \textbf
Dynamic Adversarial Reinforcement Learning for Robust Multimodal Large Language Models
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cs.AI, q-bio.NC updates on arXiv.org
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Buy versus Build an LLM: A Decision Framework for Governments
arXiv:2602.13033v2 Announce Type: replace-cross Abstract: Large Language Models (LLMs) represent a new frontier of digital infrastructure that can support a wide range of public-sector applications, from general purpose citizen services to specialized and sensitive state functions. When expanding AI access, governments face a set of strategic choices over whether to buy existing services, build domestic capabilities, or adopt hybrid approaches across different domains and use cases. These are c
Buy versus Build an LLM: A Decision Framework for Governments
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cs.AI, q-bio.NC updates on arXiv.org
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TabTracer: Monte Carlo Tree Search for Complex Table Reasoning with Large Language Models
arXiv:2602.14089v1 Announce Type: cross Abstract: Large language models (LLMs) have emerged as powerful tools for natural language table reasoning, where there are two main categories of methods. Prompt-based approaches rely on language-only inference or one-pass program generation without step-level verification. Agent-based approaches use tools in a closed loop, but verification is often local and backtracking is limited, allowing errors to propagate and increasing cost. Moreover, they rely o