Normal view

Received — 26 March 2026 ⏭

Nature - Issue - nature.com science feeds
Androgen activity in the male embryonic hindbrain drives lethal PFA ependymoma Jiao Zhang · Winnie Ong · Alexandra Rasnitsyn · Ricardo Daniel Gonzalez · Rodrigo Lopez Gutierrez · Polina Balin · Amr Saadeldin · Xiaochong Wu · Maria C. Vladoiu · Vicente Santa-Maria Lopez · Fernando Gonzalez-Salinas · Navneesh Yadav · Dinesh Mohanakrishnan · Kannan Boosi Narayana Rao · Raja Gopal Reddy Mooli · Hinda Najem · Sebastian Pacheco · Kaitlin Kharas · Cory Richman · David Przelicki · Evan Y. Wang · Haipeng Su · Rachel Naomi Curry · Runze Yang · Michelle Masayo Kameda-Smith · Bryn Livingston · David Scott · Zaili Luo · Mingyang Xia · Namal Abeysundara · Anders W. Erickson · Ncedile Mankahla · Lucas ZhongMing Hu · Chu Pan · Raul Suarez · Ning Huang · Yihao Wu · Hao Wang · Tajana Douglas · Jonelle Pallota · Steven Hébert · Karen Ng · Krystin Mantione · Heather Whetstone · Hassaan Maan · Hussein Lakkis · Juyeun Lee · Sadeesh K. Ramakrishnan · Yanxin Pei · Yujie Tang · Frank Y. Lin · Guillermo Aldave · Marco Gallo · Robert M. Friedlander · Faiyaz Notta · Laura K. Donovan · Murali Chintagumpala · Bo Wang · Yun Li · Daniel D. De Carvalho · Zhaolei Zhang · Ying M
Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10264-6Androgen activity in the male embryonic hindbrain prolongs hindbrain differentiation in male individuals and drives sex differences in the incidence and prognosis of posterior fossa type A (PFA) ependymoma, an aggressive childhood brain tumour.
25 March 2026 at 08:00

Androgen activity in the male embryonic hindbrain drives lethal PFA ependymoma

Nature - Issue - nature.com science feeds

By: Jiao Zhang · Winnie Ong · Alexandra Rasnitsyn · Ricardo Daniel Gonzalez · Rodrigo Lopez Gutierrez · Polina Balin · Amr Saadeldin · Xiaochong Wu · Maria C. Vladoiu · Vicente Santa-Maria Lopez · Fernando Gonzalez-Salinas · Navneesh Yadav · Dinesh Mohanakrishnan · Kannan Boosi Narayana Rao · Raja Gopal Reddy Mooli · Hinda Najem · Sebastian Pacheco · Kaitlin Kharas · Cory Richman · David Przelicki · Evan Y. Wang · Haipeng Su · Rachel Naomi Curry · Runze Yang · Michelle Masayo Kameda-Smith · Bryn Livingston · David Scott · Zaili Luo · Mingyang Xia · Namal Abeysundara · Anders W. Erickson · Ncedile Mankahla · Lucas ZhongMing Hu · Chu Pan · Raul Suarez · Ning Huang · Yihao Wu · Hao Wang · Tajana Douglas · Jonelle Pallota · Steven Hébert · Karen Ng · Krystin Mantione · Heather Whetstone · Hassaan Maan · Hussein Lakkis · Juyeun Lee · Sadeesh K. Ramakrishnan · Yanxin Pei · Yujie Tang · Frank Y. Lin · Guillermo Aldave · Marco Gallo · Robert M. Friedlander · Faiyaz Notta · Laura K. Donovan · Murali Chintagumpala · Bo Wang · Yun Li · Daniel D. De Carvalho · Zhaolei Zhang · Ying M

25 March 2026 at 08:00

Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10264-6

Androgen activity in the male embryonic hindbrain prolongs hindbrain differentiation in male individuals and drives sex differences in the incidence and prognosis of posterior fossa type A (PFA) ependymoma, an aggressive childhood brain tumour.

Nature Biotechnology - Issue - nature.com science feeds
Sustained nitric oxide production by engineered <i>E. coli</i> remodels the tumor microenvironment and potentiates immunotherapy Shuyu Xu · Tianjiao Zhang · Yang Song · Mengxin Wang · Ruiqi Wu · Mofan Li · Haonan Wang · Xinxin Xie · Qingfeng Chen · Xiaotu Ma · Xiaolong Liang
Nature Biotechnology, Published online: 18 March 2026; doi:10.1038/s41587-026-03054-ySolid tumors are sensitized to anti‑PD‑L1 immunotherapy by engineered E. coli to produce nitric oxide.
18 March 2026 at 08:00

Sustained nitric oxide production by engineered <i>E. coli</i> remodels the tumor microenvironment and potentiates immunotherapy

Nature Biotechnology - Issue - nature.com science feeds

By: Shuyu Xu · Tianjiao Zhang · Yang Song · Mengxin Wang · Ruiqi Wu · Mofan Li · Haonan Wang · Xinxin Xie · Qingfeng Chen · Xiaotu Ma · Xiaolong Liang

18 March 2026 at 08:00

Nature Biotechnology, Published online: 18 March 2026; doi:10.1038/s41587-026-03054-y

Solid tumors are sensitized to anti‑PD‑L1 immunotherapy by engineered E. coli to produce nitric oxide.