arXiv:2604.11557v2 Announce Type: replace Abstract: Tool-use capability is a fundamental component of LLM agents, enabling them to interact with external systems through structured function calls. However, existing research exhibits inconsistent interaction representations, largely overlooks the structural distribution of tool-use trajectories, and relies on incompatible evaluation benchmarks. We present UniToolCall, a unified framework for tool learning that standardizes the entire pipeline from toolset construction and dataset generation to evaluation. The framework curates a large tool pool of 22k+ tools and constructs a hybrid training corpus of 390k+ instances by combining 10 standardized public datasets with structurally controlled synthetic trajectories. It explicitly models diverse interaction patterns, including single-hop vs. multi-hop and single-turn vs. multi-turn, while capturing both serial and parallel execution structures. To support coherent multi-turn reasoning, we further introduce an Anchor Linkage mechanism that enforces cross-turn dependencies. Furthermore, we convert 7 public benchmarks into a unified Query--Action--Observation--Answer (QAOA) representation with fine-grained evaluation at the function-call, turn, and conversation levels. Experiments show that fine-tuning Qwen3-8B on our dataset substantially improves tool-use performance. Under the distractor-heavy Hybrid-20 setting, achieves 93.0% single-turn Strict Precision, outperforming commercial models including GPT, Gemini, and Claude.

npj Digital Medicine, Published online: 26 May 2026; doi:10.1038/s41746-026-02798-w

Personalized neoadjuvant treatment regimen selection in locally advanced rectal cancer based on regimen-specific response modeling

arXiv:2604.01907v1 Announce Type: cross Abstract: Annotated 3D scene data is scarce and expensive to acquire, while abundant unlabeled videos are readily available on the internet. In this paper, we demonstrate that carefully designed data engines can leverage web-curated, unlabeled videos to automatically generate training data, to facilitate end-to-end models in 3D scene understanding alongside human-annotated datasets. We identify and analyze bottlenecks in automated data generation, revealing critical factors that determine the efficiency and effectiveness of learning from unlabeled data. To validate our approach across different perception granularities, we evaluate on three tasks spanning low-level perception, i.e., 3D object detection and instance segmentation, to high-evel reasoning, i.e., 3D spatial Visual Question Answering (VQA) and Vision-Lanugage Navigation (VLN). Models trained on our generated data demonstrate strong zero-shot performance and show further improvement after finetuning. This demonstrates the viability of leveraging readily available web data as a path toward more capable scene understanding systems.

npj Digital Medicine, Published online: 28 March 2026; doi:10.1038/s41746-026-02575-9

A multicenter randomized clinical trial of portable transcranial alternating current stimulation for major depressive disorder

arXiv:2603.06859v1 Announce Type: cross Abstract: Cooperative multi-agent reinforcement learning (MARL) systems powered by large language models (LLMs) are frequently optimized via sparse terminal-only feedback. This shared signal entangles upstream decisions, obstructing accurate decision-level credit assignment. To address this trajectory-level diffusion, we introduce Contextual Counterfactual Credit Assignment (\textbf{\texttt{C3}}). Instead of distributing rewards across an entire episode, \textbf{\texttt{C3}} isolates the causal impact of individual messages by freezing the exact transcript-derived context, evaluating context-matched alternatives via fixed-continuation replay, and applying a leave-one-out (LOO) baseline. This localized intervention extracts unbiased, low-variance marginal advantages for standard policy-gradient optimization. Evaluated across five mathematical and coding benchmarks under matched budgets, \textbf{\texttt{C3}} improves terminal performance over established baselines. Mechanistic diagnostics further show that these gains are accompanied by higher credit fidelity, lower contextual variance, and stronger inter-agent causal dependence. Our code is available at https://github.com/EIT-EAST-Lab/C3.

arXiv:2509.23519v2 Announce Type: replace-cross Abstract: Retrieval-Augmented Generation (RAG) enhances Large Language Models by grounding their outputs in external documents. These systems, however, remain vulnerable to attacks on the retrieval corpus, such as prompt injection. RAG-based search systems (e.g., Google's Search AI Overview) present an interesting setting for studying and protecting against such threats, as defense algorithms can benefit from built-in reliability signals -- like document ranking -- and represent a non-LLM challenge for the adversary due to decades of work to thwart SEO. Motivated by, but not limited to, this scenario, this work introduces ReliabilityRAG, a framework for adversarial robustness that explicitly leverages reliability information of retrieved documents. Our first contribution adopts a graph-theoretic perspective to identify a "consistent majority" among retrieved documents to filter out malicious ones. We introduce a novel algorithm based on finding a Maximum Independent Set (MIS) on a document graph where edges encode contradiction. Our MIS variant explicitly prioritizes higher-reliability documents and provides provable robustness guarantees against bounded adversarial corruption under natural assumptions. Recognizing the computational cost of exact MIS for large retrieval sets, our second contribution is a scalable weighted sample and aggregate framework. It explicitly utilizes reliability information, preserving some robustness guarantees while efficiently handling many documents. We present empirical results showing ReliabilityRAG provides superior robustness against adversarial attacks compared to prior methods, maintains high benign accuracy, and excels in long-form generation tasks where prior robustness-focused methods struggled. Our work is a significant step towards more effective, provably robust defenses against retrieved corpus corruption in RAG.