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cs.AI, q-bio.NC updates on arXiv.org
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BlueLM-GUI Technical Report: A Real-Device-Centric Flywheel for Self-Improving Mobile GUI Agents
arXiv:2609.12394v1 Announce Type: new Abstract: Mobile GUI agents are shifting from multi-module frameworks to native models trained end-to-end, yet industrial deployment faces three persistent gaps. Sandbox training produces a distribution mismatch with production environments; expensive real-device failures remain underutilized; and fixed benchmarks saturate, losing the power to guide iteration. We present BlueLM-GUI, a 35B-A3B mobile GUI agent built as a real-device-centric flywheel that clo
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cs.AI, q-bio.NC updates on arXiv.org
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Mode-as-Sequence: Translating Multimodal Motion Prediction into Unified Sequential Mode Modeling
arXiv:2605.24037v1 Announce Type: cross Abstract: Multimodal motion forecasting is inherently under-supervised: each training scene provides only one realized future, yet multiple plausible futures exist. This sparse supervision often leads to mode collapse (redundant hypotheses and insufficient mode coverage) and unreliable confidence ranking when predicting a small set of trajectories. We propose Mode-as-Sequence, a unified decoding framework that translates an unordered mode set into an orde
Mode-as-Sequence: Translating Multimodal Motion Prediction into Unified Sequential Mode Modeling
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cs.AI, q-bio.NC updates on arXiv.org
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Metropolis-Scale Resilient and Trustworthy Traffic Flow Inference Using Multi-Source Data
arXiv:2605.25004v1 Announce Type: cross Abstract: Inferring network-wide traffic states from sparse observations with high accuracy and trustworthy uncertainty quantification is essential for intelligent transportation systems, yet it remains challenging due to the underdetermined nature of the problem, multifaceted disturbances in sensing networks, and the inherent conflicts among multiple inference sub-tasks when modeled jointly. We propose the Task-Aware Attentive Neural Process (TA-ANP), a
Metropolis-Scale Resilient and Trustworthy Traffic Flow Inference Using Multi-Source Data
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cs.AI, q-bio.NC updates on arXiv.org
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Can LLMs Time Travel? Enhancing Temporal Consistency in Legal Agentic Search through Reinforcement Learning
arXiv:2605.25920v1 Announce Type: cross Abstract: While large language models (LLMs) augmented with agentic search capabilities show promise for legal reasoning, they overlook a fundamental constraint that applicable law must match the temporal context of each case, as retroactive application of statutes violates core legal principles and leads to erroneous conclusions. Our observations reveal that current legal LLMs suffer from temporal bias anchored to their training cutoff, while search agen
Can LLMs Time Travel? Enhancing Temporal Consistency in Legal Agentic Search through Reinforcement Learning
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cs.AI, q-bio.NC updates on arXiv.org
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L-Drive: Beyond a Single Mapping-Latent Context Drives Time Series Forecasting
arXiv:2605.17730v2 Announce Type: replace-cross Abstract: Mainstream methods for multivariate time-series forecasting largely follow the Direct-Mapping paradigm. They learn a unified mapping from history to the future in the observation space to fit value-level dependencies. However, real-world systems often undergo distribution shifts and regime changes. In such cases, a unified mapping can exhibit response lag around turning points, causing error accumulation within the switching window and r
L-Drive: Beyond a Single Mapping-Latent Context Drives Time Series Forecasting
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Nature - Issue - nature.com science feeds
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Advancing solar and wind penetration in China through energy complementarity
Nature, Published online: 20 May 2026; doi:10.1038/s41586-026-10570-zUsing high-resolution satellite imagery combined with a deep-learning-based framework to build a national energy inventory enables a data-driven assessment of solar–wind complementarity strategies to reduce power variability and enhance renewable energy penetration across China.
Advancing solar and wind penetration in China through energy complementarity
Nature, Published online: 20 May 2026; doi:10.1038/s41586-026-10570-z
Using high-resolution satellite imagery combined with a deep-learning-based framework to build a national energy inventory enables a data-driven assessment of solar–wind complementarity strategies to reduce power variability and enhance renewable energy penetration across China.-
Nature - Issue - nature.com science feeds
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Accelerating scientific discovery with Co-Scientist
Nature, Published online: 19 May 2026; doi:10.1038/s41586-026-10644-yAccelerating scientific discovery with Co-Scientist
Accelerating scientific discovery with Co-Scientist
Nature, Published online: 19 May 2026; doi:10.1038/s41586-026-10644-y
Accelerating scientific discovery with Co-Scientist-
Omics in Gastric
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Integrative multi-omics analysis identifies stromal-immune crosstalk as a determinant of immunotherapy efficacy and establishes a prognostic signature in gastric cancer
Comput Biol Chem. 2026 Apr 23;124(Pt 1):109095. doi: 10.1016/j.compbiolchem.2026.109095. Online ahead of print.ABSTRACTImmune checkpoint inhibitors like pembrolizumab exhibit variable efficacy in metastatic gastric cancer (GC). This study aimed to identify molecular drivers of pembrolizumab response, explore mechanisms of immune checkpoint inhibitors (ICIs) efficacy, and develop a prognostic signature. Transcriptomic analysis of pembrolizumab-treated GC (TIGER database) identified 165 response-a
Integrative multi-omics analysis identifies stromal-immune crosstalk as a determinant of immunotherapy efficacy and establishes a prognostic signature in gastric cancer
Comput Biol Chem. 2026 Apr 23;124(Pt 1):109095. doi: 10.1016/j.compbiolchem.2026.109095. Online ahead of print.
ABSTRACT
Immune checkpoint inhibitors like pembrolizumab exhibit variable efficacy in metastatic gastric cancer (GC). This study aimed to identify molecular drivers of pembrolizumab response, explore mechanisms of immune checkpoint inhibitors (ICIs) efficacy, and develop a prognostic signature. Transcriptomic analysis of pembrolizumab-treated GC (TIGER database) identified 165 response-associated differentially expressed genes (DEGs). Functional annotation and single-cell RNA sequencing (scRNA-seq) data from the Gene Expression Omnibus (GEO) revealed that responder-upregulated genes (R-DEGs) were enriched in immune activation pathways and mainly localized to CD8 + T/NK cells. In contrast, non-responder-upregulated genes (D-DEGs) were linked to extracellular matrix (ECM) remodeling and mainly expressed in fibroblasts/endothelial cells. CellChat analysis demonstrated that key DEGs mediate immune-stromal crosstalk via MHC-I and collagen/laminin signaling. A prognostic signature (Lasso-StepCox[forward] Riskscore; LSR: APOD, APOH, BATF2, GJA1, MAGED1, SLC5A1, SLCO2A1, VWF, VCAN) was derived and validated in four independent GC cohorts from the GEO and Cancer Genome Atlas (TCGA) database. Multi-omics analyses showed that LSR-high tumors exhibited aggressive clinicopathological features, increased stromal components, reduced cytotoxic immune infiltration, diminished tumor mutational burden (TMB), and poorer prognosis. Immunohistochemistry (IHC) and spatial transcriptomics in GC showed that stromal VWF/VCAN expression correlates with reduced CD8⁺ T cell granzyme B expression, suggesting T cell dysfunction. High VWF expression in GC predicted poor survival, and a combined VWF/VCAN score showed enhanced prognostic stratification. This study highlights stromal-immune crosstalk as a driver of pembrolizumab resistance and provides a signature as a clinical tool for prognosis and personalized therapy in metastatic GC.
PMID:42068630 | DOI:10.1016/j.compbiolchem.2026.109095
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cs.AI, q-bio.NC updates on arXiv.org
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Group Representational Position Encoding
arXiv:2512.07805v5 Announce Type: replace-cross Abstract: We present GRAPE (Group Representational Position Encoding), a unified framework for positional encoding based on group actions. GRAPE unifies two families of mechanisms: (i) multiplicative rotations (Multiplicative GRAPE) in $\operatorname{SO}(d)$ and (ii) additive logit biases (Additive GRAPE) arising from unipotent actions in the general linear group $\mathrm{GL}$. In Multiplicative GRAPE, a position $n \in \mathbb{Z}$ (or $t \in \mat
Group Representational Position Encoding
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cs.AI, q-bio.NC updates on arXiv.org
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Derived Fields Preserve Fine-Scale Detail in Budgeted Neural Simulators
arXiv:2603.29224v1 Announce Type: cross Abstract: Fine-scale-faithful neural simulation under fixed storage budgets remains challenging. Many existing methods reduce high-frequency error by improving architectures, training objectives, or rollout strategies. However, under budgeted coarsen-quantize-decode pipelines, fine detail can already be lost when the carried state is constructed. In the canonical periodic incompressible Navier-Stokes setting, we show that primitive and derived fields unde
Derived Fields Preserve Fine-Scale Detail in Budgeted Neural Simulators
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cs.AI, q-bio.NC updates on arXiv.org
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Enhancing AI-Based Tropical Cyclone Track and Intensity Forecasting via Systematic Bias Correction
arXiv:2603.22314v1 Announce Type: cross Abstract: Tropical cyclones (TCs) pose severe threats to life, infrastructure, and economies in tropical and subtropical regions, underscoring the critical need for accurate and timely forecasts of both track and intensity. Recent advances in AI-based weather forecasting have shown promise in improving TC track forecasts. However, these systems are typically trained on coarse-resolution reanalysis data (e.g., ERA5 at 0.25 degree), which constrains predict
Enhancing AI-Based Tropical Cyclone Track and Intensity Forecasting via Systematic Bias Correction
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cs.AI, q-bio.NC updates on arXiv.org
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CognitionCapturerPro: Towards High-Fidelity Visual Decoding from EEG/MEG via Multi-modal Information and Asymmetric Alignment
arXiv:2603.12722v1 Announce Type: cross Abstract: Visual stimuli reconstruction from EEG remains challenging due to fidelity loss and representation shift. We propose CognitionCapturerPro, an enhanced framework that integrates EEG with multi-modal priors (images, text, depth, and edges) via collaborative training. Our core contributions include an uncertainty-weighted similarity scoring mechanism to quantify modality-specific fidelity and a fusion encoder for integrating shared representations.
CognitionCapturerPro: Towards High-Fidelity Visual Decoding from EEG/MEG via Multi-modal Information and Asymmetric Alignment
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cs.AI, q-bio.NC updates on arXiv.org
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Mozi: Governed Autonomy for Drug Discovery LLM Agents
arXiv:2603.03655v1 Announce Type: new Abstract: Tool-augmented large language model (LLM) agents promise to unify scientific reasoning with computation, yet their deployment in high-stakes domains like drug discovery is bottlenecked by two critical barriers: unconstrained tool-use governance and poor long-horizon reliability. In dependency-heavy pharmaceutical pipelines, autonomous agents often drift into irreproducible trajectories, where early-stage hallucinations multiplicatively compound in
Mozi: Governed Autonomy for Drug Discovery LLM Agents
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cs.AI, q-bio.NC updates on arXiv.org
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MedLA: A Logic-Driven Multi-Agent Framework for Complex Medical Reasoning with Large Language Models
arXiv:2509.23725v3 Announce Type: replace Abstract: Answering complex medical questions requires not only domain expertise and patient-specific information, but also structured and multi-perspective reasoning. Existing multi-agent approaches often rely on fixed roles or shallow interaction prompts, limiting their ability to detect and resolve fine-grained logical inconsistencies. To address this, we propose \textsc{MedLA}, a logic-driven multi-agent framework built on large language models. Eac
MedLA: A Logic-Driven Multi-Agent Framework for Complex Medical Reasoning with Large Language Models
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cs.AI, q-bio.NC updates on arXiv.org
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Group Representational Position Encoding
arXiv:2512.07805v4 Announce Type: replace-cross Abstract: We present GRAPE (Group Representational Position Encoding), a unified framework for positional encoding based on group actions. GRAPE unifies two families of mechanisms: (i) multiplicative rotations (Multiplicative GRAPE) in $\operatorname{SO}(d)$ and (ii) additive logit biases (Additive GRAPE) arising from unipotent actions in the general linear group $\mathrm{GL}$. In Multiplicative GRAPE, a position $n \in \mathbb{Z}$ (or $t \in \mat
Group Representational Position Encoding
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cs.AI, q-bio.NC updates on arXiv.org
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Transferable XAI: Relating Understanding Across Domains with Explanation Transfer
arXiv:2602.13675v1 Announce Type: cross Abstract: Current Explainable AI (XAI) focuses on explaining a single application, but when encountering related applications, users may rely on their prior understanding from previous explanations. This leads to either overgeneralization and AI overreliance, or burdensome independent memorization. Indeed, related decision tasks can share explanatory factors, but with some notable differences; e.g., body mass index (BMI) affects the risks for heart diseas
Transferable XAI: Relating Understanding Across Domains with Explanation Transfer
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cs.AI, q-bio.NC updates on arXiv.org
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Comparables XAI: Faithful Example-based AI Explanations with Counterfactual Trace Adjustments
arXiv:2602.13784v1 Announce Type: cross Abstract: Explaining with examples is an intuitive way to justify AI decisions. However, it is challenging to understand how a decision value should change relative to the examples with many features differing by large amounts. We draw from real estate valuation that uses Comparables-examples with known values for comparison. Estimates are made more accurate by hypothetically adjusting the attributes of each Comparable and correspondingly changing the val
Comparables XAI: Faithful Example-based AI Explanations with Counterfactual Trace Adjustments
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cs.AI, q-bio.NC updates on arXiv.org
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GeoEyes: On-Demand Visual Focusing for Evidence-Grounded Understanding of Ultra-High-Resolution Remote Sensing Imagery
arXiv:2602.14201v1 Announce Type: cross Abstract: The "thinking-with-images" paradigm enables multimodal large language models (MLLMs) to actively explore visual scenes via zoom-in tools. This is essential for ultra-high-resolution (UHR) remote sensing VQA, where task-relevant cues are sparse and tiny. However, we observe a consistent failure mode in existing zoom-enabled MLLMs: Tool Usage Homogenization, where tool calls collapse into task-agnostic patterns, limiting effective evidence acquisi
GeoEyes: On-Demand Visual Focusing for Evidence-Grounded Understanding of Ultra-High-Resolution Remote Sensing Imagery
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cs.AI, q-bio.NC updates on arXiv.org
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Making Slow Thinking Faster: Compressing LLM Chain-of-Thought via Step Entropy
arXiv:2508.03346v2 Announce Type: replace Abstract: Large Language Models (LLMs) using Chain-of-Thought (CoT) prompting excel at complex reasoning but generate verbose thought processes with considerable redundancy, leading to increased inference costs and reduced efficiency. We introduce a novel CoT compression framework based on step entropy, a metric that quantifies \emph{the informational contribution of individual reasoning steps} to identify redundancy. Through theoretical analysis and ex