Normal view
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cs.AI, q-bio.NC updates on arXiv.org
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How Good Are Frontier Models at Physics? Expert Re-Grading Reveals Broken Evaluations and Near-Saturation of Leading Benchmarks
arXiv:2609.13009v1 Announce Type: new Abstract: Low reported scores on leading physics benchmarks, including those featured in the Artificial Analysis Intelligence Index (2026), suggest that frontier language models still struggle with advanced physics, a demanding test of their scientific reasoning and quantitative problem-solving abilities. Yet this impression does not always align with domain experts' experiences using these models in their work. We revisit these reported findings by evaluat
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cs.AI, q-bio.NC updates on arXiv.org
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Embodied-BenchForge: A Closed-Loop Agentic Workflow for Embodied Benchmark Construction
arXiv:2609.13082v1 Announce Type: new Abstract: Agentic systems offer a promising way to automate embodied benchmark construction, but existing approaches typically cover isolated stages or remain specialized to predefined environments and task families. More importantly, multi-step construction produces dependent intermediate artifacts that are often passed downstream without artifact-specific verification, allowing local defects to propagate into the final benchmark. We present Embodied-Bench
Embodied-BenchForge: A Closed-Loop Agentic Workflow for Embodied Benchmark Construction
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cs.AI, q-bio.NC updates on arXiv.org
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Iterative Refinement Neural Operators are Learned Fixed-Point Solvers: A Principled Approach to Spectral Bias Mitigation
arXiv:2605.24041v2 Announce Type: cross Abstract: Neural operators serve as fast, data-driven surrogates for scientific modeling but typically rely on a monolithic, single-pass inference procedure that struggles to resolve high-frequency details, a limitation known as spectral bias. We introduce the Iterative Refinement Neural Operator (IRNO), which augments pre-trained operators with a learned refinement module iteratively applied via fixed-point iteration. IRNO decomposes the prediction into
Iterative Refinement Neural Operators are Learned Fixed-Point Solvers: A Principled Approach to Spectral Bias Mitigation
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cs.AI, q-bio.NC updates on arXiv.org
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Federation over Text: Insight Sharing for Multi-Agent Reasoning
arXiv:2604.16778v2 Announce Type: replace-cross Abstract: We propose a federated learning-like framework, Federation over Text (FoT), that enables multiple clients solving different tasks to collectively generate a shared library of metacognitive insights by iteratively federating their local reasoning processes without sharing actual problem instances or task instructions. Instead of federation over gradients (e.g., as in distributed training), FoT operates at the semantic level without any gr
Federation over Text: Insight Sharing for Multi-Agent Reasoning
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Nature - Issue - nature.com science feeds
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Satellite imagery reveals increasing volatility in human night-time activity
Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10260-wDaily satellite data reveal that Earth’s artificial lights at night are highly volatile, with frequent brightening and dimming between 2014 and 2022.
Satellite imagery reveals increasing volatility in human night-time activity
Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10260-w
Daily satellite data reveal that Earth’s artificial lights at night are highly volatile, with frequent brightening and dimming between 2014 and 2022.-
AAAS: Table of Contents
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A high-throughput selection system for fast-acting covalent protein drugs
Science, Ahead of Print.
A high-throughput selection system for fast-acting covalent protein drugs
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cs.AI, q-bio.NC updates on arXiv.org
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Long-Document QA with Chain-of-Structured-Thought and Fine-Tuned SLMs
arXiv:2603.29232v1 Announce Type: cross Abstract: Large language models (LLMs) are widely applied to data analytics over documents, yet direct reasoning over long, noisy documents remains brittle and error-prone. Hence, we study document question answering (QA) that consolidates dispersed evidence into a structured output (e.g., a table, graph, or chunks) to support reliable, verifiable QA. We propose a two-pillar framework, LiteCoST, to achieve both high accuracy and low latency with small lan
Long-Document QA with Chain-of-Structured-Thought and Fine-Tuned SLMs
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Nature - Issue - nature.com science feeds
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Dual-symmetry-guided assembly of complex lattices
Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10364-3A dual-symmetry-guided strategy is used to assemble a broad class of complex Archimedean lattices and two-dimensional quasicrystalline structures, providing a general and experimentally accessible route to complex-symmetry materials.
Dual-symmetry-guided assembly of complex lattices
Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10364-3
A dual-symmetry-guided strategy is used to assemble a broad class of complex Archimedean lattices and two-dimensional quasicrystalline structures, providing a general and experimentally accessible route to complex-symmetry materials.-
(Multiomics OR Omics) AND (Lung OR gastric OR Hepatocellular)
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AI-guided multi-omics analysis identifies NPC1-modulated susceptibility to SARS-CoV-2 infection under PM(2.5) exposure
Nat Commun. 2026 Mar 30. doi: 10.1038/s41467-026-71196-3. Online ahead of print.ABSTRACTExposure to airborne fine particulate matter (PM2.5) has been linked to increased risk of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, yet the underlying mechanisms remain unclear. Here, by leveraging a fine-tuned foundation model of single-cell transcriptomics, we uncover shared transcriptional signatures between PM2.5 exposure and SARS-CoV-2 infection. We further validate this
AI-guided multi-omics analysis identifies NPC1-modulated susceptibility to SARS-CoV-2 infection under PM(2.5) exposure
Nat Commun. 2026 Mar 30. doi: 10.1038/s41467-026-71196-3. Online ahead of print.
ABSTRACT
Exposure to airborne fine particulate matter (PM2.5) has been linked to increased risk of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, yet the underlying mechanisms remain unclear. Here, by leveraging a fine-tuned foundation model of single-cell transcriptomics, we uncover shared transcriptional signatures between PM2.5 exposure and SARS-CoV-2 infection. We further validate this association using population-level epidemiological analyses and perform genome-wide association studies (GWAS) to identify genetic variants that modulate infection risk under PM2.5 exposure. In addition, we identify NPC1 as a key modulator involved in SARS-CoV-2 infection efficiency under virus-laden PM2.5 exposure through integrative functional genomic analyses and in vitro experiments. Our findings suggest that PM2.5 facilitates viral entry through an NPC1-modulated endo-lysosomal pathway, providing a mechanistic explanation for observed pollution-related susceptibility. By integrating artificial intelligence (AI)-guided transcriptomics, epidemiology, GWAS, functional genomics, and in vitro verification, our study elucidates how environmental and genetic factors jointly influence SARS-CoV-2 susceptibility. This work highlights how AI-assisted multi-omics integration systematically decodes the health impacts of environmental exposures from molecular to population levels and informs air quality policy and infectious disease preparedness.
PMID:41912520 | DOI:10.1038/s41467-026-71196-3
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cs.AI, q-bio.NC updates on arXiv.org
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Towards Self-Robust LLMs: Intrinsic Prompt Noise Resistance via CoIPO
arXiv:2603.03314v1 Announce Type: cross Abstract: Large language models (LLMs) have demonstrated remarkable and steadily improving performance across a wide range of tasks. However, LLM performance may be highly sensitive to prompt variations especially in scenarios with limited openness or strict output formatting requirements, indicating insufficient robustness. In real-world applications, user prompts provided to LLMs often contain imperfections, which may undermine the quality of the model'
Towards Self-Robust LLMs: Intrinsic Prompt Noise Resistance via CoIPO
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cs.AI, q-bio.NC updates on arXiv.org
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To Think or Not To Think, That is The Question for Large Reasoning Models in Theory of Mind Tasks
arXiv:2602.10625v3 Announce Type: replace Abstract: Theory of Mind (ToM) assesses whether models can infer hidden mental states such as beliefs, desires, and intentions, which is essential for natural social interaction. Although recent progress in Large Reasoning Models (LRMs) has boosted step-by-step inference in mathematics and coding, it is still underexplored whether this benefit transfers to socio-cognitive skills. We present a systematic study of nine advanced Large Language Models (LLMs
To Think or Not To Think, That is The Question for Large Reasoning Models in Theory of Mind Tasks
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cs.AI, q-bio.NC updates on arXiv.org
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SenTSR-Bench: Thinking with Injected Knowledge for Time-Series Reasoning
arXiv:2602.19455v1 Announce Type: cross Abstract: Time-series diagnostic reasoning is essential for many applications, yet existing solutions face a persistent gap: general reasoning large language models (GRLMs) possess strong reasoning skills but lack the domain-specific knowledge to understand complex time-series patterns. Conversely, fine-tuned time-series LLMs (TSLMs) understand these patterns but lack the capacity to generalize reasoning for more complicated questions. To bridge this gap,