arXiv:2607.12455v2 Announce Type: replace Abstract: Quantitative strategy optimization remains largely manual, requiring domain experts to identify weak signals, tune risk-control rules, and repeatedly validate iterative revisions. Large language models can accelerate this process, but directly relying on them to rewrite trading strategies often introduces hallucinated edits, strategy drift, and backtest overfitting. We propose EVOQUANT, a self-Evolving Verifier-guided framework for strategy Optimization in Quantitative trading. Our method utilizes LLMs to deeply diagnose performance bottlenecks, generates semantically controlled candidate edits, selects the best strategy through a multi-stage verification pipeline, and distills optimization experience into reusable knowledge for continual self-improvement. We evaluate our method using seven representative strategies: four from the A-share market and three from the Crypto market. Experimental results show that our method significantly improves the Sharpe ratio across all tested strategies: the average test Sharpe increases from -0.298 to 0.538, and the best-performing strategy achieves a 199% relative improvement. Ablation studies and stress tests under stricter conditions further validate the effectiveness and robustness of the framework. Overall, this work transforms quantitative strategy optimization from costly manual trial and error into an automated and verifiable iterative paradigm, offering a new path for applying large language models to financial strategy research.

Nature, Published online: 07 September 2026; doi:10.1038/s41586-026-11094-2

Author Correction: A mouse brain stereotaxic topographic atlas with isotropic 1-μm resolution

Ancient DNA from 149 individuals at 11 sites in Gansu, China, dated to around 4,700–3,000 years ago, reveals human population history during early transcontinental exchanges of agriculture and technology, as well as contemporary social practices, at the large Mogou cemetery.

arXiv:2605.24636v2 Announce Type: new Abstract: While large language models (LLMs) hold transformative potential for medicine, their reasoning robustness and safety in real-world clinical scenarios remain critically underexplored, particularly in dentistry. Here we introduce GlobalDentBench, the first multinational dental benchmark, featuring a taxonomy that encompasses 14 dental specialties across 88 countries and regions spanning six continents. The benchmark comprises 8,978 expert-validated questions across three formats (multiple-choice, short-answer, and case-based questions) and assesses three progressive reasoning levels: knowledge recall (L1), routine reasoning (L2), and individualized reasoning (L3). To ensure data quality, the automated construction framework was calibrated by six senior dentists, achieving expert agreement rates of 99.98% for multiple-choice and short-answer questions and 96.78% for the more complex case-based questions. Evaluation of 12 frontier LLMs on GlobalDentBench revealed a sharp, stepwise performance degradation with increasing reasoning complexity. Specifically, accuracy plummeted from 81.34% on multiple-choice to 64.53% on short-answer and 22.34% on case-based questions, while declining markedly from 74.01% at L1 to 55.64% at L2 and 35.71% at L3. More critically, risk analysis of real-world dental cases demonstrated an alarming overall unsafe rate of 31.01% in LLM-generated clinical recommendations, with 4.51% posing risks of irreversible patient harm and risks particularly pronounced in specialties such as orthodontics. These findings expose fundamental limitations in the medical reasoning and safety of current LLMs. Consequently, GlobalDentBench provides a scalable foundation for trustworthy clinical AI evaluation, underscoring the urgent need for rigorous validation before the safe deployment of these models in healthcare.

arXiv:2604.04475v1 Announce Type: cross Abstract: Leveraging Large Language Models (LLMs) as federated learning (FL)-based time series foundation models offers a promising way to transfer the generalization capabilities of LLMs to time series data while preserving access to private data. However, the semantic misalignment between time-series data and the text-centric latent space of existing LLMs often leads to degraded performance. Meanwhile, the parameter-sharing mechanism in existing FL methods model heterogeneous cross-domain time-series data into a unified continuous latent space, which contradicts the fact that time-series semantics frequently manifest as discrete and recurring regimes. To address these limitations, we propose \textsc{FeDPM}, a federated framework for time-series foundation models based on discrete prototypical memories. Specifically, we learn local prototypical memory priors for intra-domain time-series data. We then align cross-domain memories to promote a unified discrete latent space and introduce a domain-specific memory update mechanism to balance shared and personalized prototypical knowledge. Extensive experiments demonstrate the efficiency and effectiveness of \textsc{FeDPM}. The code is publicly available at https://anonymous.4open.science/r/FedUnit-64D1.

arXiv:2603.20670v2 Announce Type: replace Abstract: The rapid growth in the volume, variety, and velocity of geospatial data has created data ecosystems that are highly distributed, heterogeneous, and semantically inconsistent. Existing data catalogs, portals, and infrastructures still rely largely on keyword-based search with limited semantic support, which often fails to capture user intent and leads to weak retrieval performance. To address these challenges, this study proposes a knowledge graph-driven multi-agent framework for intelligent geospatial data discovery, powered by large language models. The framework introduces a unified geospatial metadata ontology as a semantic mediation layer to align heterogeneous metadata standards across platforms and constructs a geospatial metadata knowledge graph to explicitly model datasets and their multidimensional relationships. Building on the structured representation, the framework adopts a multi-agent collaborative architecture to perform intent parsing, knowledge graph retrieval, and answer synthesis, forming an interpretable and closed-loop discovery process from user queries to results. Results from representative use cases and performance evaluation show that the framework substantially improves intent matching accuracy, ranking quality, recall, and discovery transparency compared with traditional systems. This study advances geospatial data discovery toward a more semantic, intent-aware, and intelligent paradigm, providing a practical foundation for next-generation intelligent and autonomous spatial data infrastructures and contributing to the broader vision of Autonomous GIS.

arXiv:2603.08059v1 Announce Type: cross Abstract: With the rapid advancement of commercial multi-modal models, image editing has garnered significant attention due to its widespread applicability in daily life. Despite impressive progress, existing image editing systems, particularly closed-source or proprietary models, often struggle with complex, indirect, or multi-step user instructions. These limitations hinder their ability to perform nuanced, context-aware edits that align with human intent. In this work, we propose ImageEdit-R1, a multi-agent framework for intelligent image editing that leverages reinforcement learning to coordinate high-level decision-making across a set of specialized, pretrained vision-language and generative agents. Each agent is responsible for distinct capabilities--such as understanding user intent, identifying regions of interest, selecting appropriate editing actions, and synthesizing visual content--while reinforcement learning governs their collaboration to ensure coherent and goal-directed behavior. Unlike existing approaches that rely on monolithic models or hand-crafted pipelines, our method treats image editing as a sequential decision-making problem, enabling dynamic and context-aware editing strategies. Experimental results demonstrate that ImageEdit-R1 consistently outperforms both individual closed-source diffusion models and alternative multi-agent framework baselines across multiple image editing datasets.

arXiv:2601.19961v3 Announce Type: replace-cross Abstract: We present MeanCache, a training-free caching framework for efficient Flow Matching inference. Existing caching methods reduce redundant computation but typically rely on instantaneous velocity information (e.g., feature caching), which often leads to severe trajectory deviations and error accumulation under high acceleration ratios. MeanCache introduces an average-velocity perspective: by leveraging cached Jacobian--vector products (JVP) to construct interval average velocities from instantaneous velocities, it effectively mitigates local error accumulation. To further improve cache timing and JVP reuse stability, we develop a trajectory-stability scheduling strategy as a practical tool, employing a Peak-Suppressed Shortest Path under budget constraints to determine the schedule. Experiments on FLUX.1, Qwen-Image, and HunyuanVideo demonstrate that MeanCache achieves 4.12X and 4.56X and 3.59X acceleration, respectively, while consistently outperforming state-of-the-art caching baselines in generation quality. We believe this simple yet effective approach provides a new perspective for Flow Matching inference and will inspire further exploration of stability-driven acceleration in commercial-scale generative models.

arXiv:2510.10689v2 Announce Type: replace Abstract: Recent advances in multimodal large language models (MLLMs) have demonstrated substantial potential in video understanding. However, existing benchmarks fail to comprehensively evaluate synergistic reasoning capabilities across audio and visual modalities, often neglecting either one of the modalities or integrating them in a logically inconsistent manner. To bridge this gap, we introduce OmniVideoBench, a large-scale and rigorously designed benchmark dedicated to assessing synergistic audio-visual understanding, with a strong emphasis on modality complementarity and logical consistency. Specifically, OmniVideoBench comprises 1000 high-quality question-answer(QA) pairs, each annotated with step-by-step reasoning traces, derived from 628 diverse videos ranging from several seconds to 30 minutes, and manually verified to guarantee complete correctness and uniqueness. Moreover, OmniVideoBench encompasses 13 carefully designed question types, covering temporal reasoning, spatial localization, counting, causal inference, summarization, and beyond, thereby capturing the essential challenges of video understanding. Evaluation of multiple MLLMs on OmniVideoBench reveals a pronounced gap between model performance and human reasoning, with open-source models lagging significantly behind their closed-source counterparts, underscoring the inherent difficulty of genuine audio-visual reasoning. We will release OmniVideoBench to foster the development of MLLMs with stronger and more generalizable reasoning capabilities.