Normal view
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cs.AI, q-bio.NC updates on arXiv.org
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Tracing and Coordinating Cross-Layer Influence for Multimodal Model Merging
arXiv:2609.12897v1 Announce Type: new Abstract: Multimodal model merging aims to consolidate task experts into a single model that retains their complementary capabilities. Most unimodal model merging methods combine expert updates within individual layers, and multimodal approaches largely follow this design. However, an expert update changes the representations passed to subsequent layers, allowing its influence to propagate across depth and affect how visual and textual information interact.
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cs.AI, q-bio.NC updates on arXiv.org
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Behavior Quotient Learning for Low-Rank Adaptation of LLM Agents
arXiv:2609.12896v1 Announce Type: cross Abstract: LLM-based agents rely on heterogeneous interaction capabilities to accomplish complex tasks. Existing approaches often distribute these capabilities across multiple LoRA adapters, which increases adapter storage requirements and introduces routing overhead during inference. A single LoRA avoids this overhead, but learning from diverse agent trajectories under a fixed rank budget presents two challenges. First, trajectories with different interac
Behavior Quotient Learning for Low-Rank Adaptation of LLM Agents
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npj Digital Medicine
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Deep learning combined habitat radiomics analysis of central lymph node metastasis in papillary thyroid carcinoma
npj Digital Medicine, Published online: 12 September 2026; doi:10.1038/s41746-026-03203-2Deep learning combined habitat radiomics analysis of central lymph node metastasis in papillary thyroid carcinoma
Deep learning combined habitat radiomics analysis of central lymph node metastasis in papillary thyroid carcinoma
npj Digital Medicine, Published online: 12 September 2026; doi:10.1038/s41746-026-03203-2
Deep learning combined habitat radiomics analysis of central lymph node metastasis in papillary thyroid carcinoma-
cs.AI, q-bio.NC updates on arXiv.org
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M$^\star$: Every Task Deserves Its Own Memory Harness
arXiv:2604.11811v2 Announce Type: replace-cross Abstract: Large language model agents rely on specialized memory systems to accumulate and reuse knowledge during extended interactions. Recent architectures typically adopt a fixed memory design tailored to specific domains, such as semantic retrieval for conversations or skills reused for coding. However, a memory system optimized for one purpose frequently fails to transfer to others. To address this limitation, we introduce M$^\star$, a method
M$^\star$: Every Task Deserves Its Own Memory Harness
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Nature Biotechnology - Issue - nature.com science feeds
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Sequence Display enables large-scale sequence–activity datasets for rapid protein evolution
Nature Biotechnology, Published online: 08 April 2026; doi:10.1038/s41587-026-03087-3Sequence Display maps protein variant activities to a sequencing-based readout.
Sequence Display enables large-scale sequence–activity datasets for rapid protein evolution
Nature Biotechnology, Published online: 08 April 2026; doi:10.1038/s41587-026-03087-3
Sequence Display maps protein variant activities to a sequencing-based readout.-
cs.AI, q-bio.NC updates on arXiv.org
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ClawArena: Benchmarking AI Agents in Evolving Information Environments
arXiv:2604.04202v1 Announce Type: cross Abstract: AI agents deployed as persistent assistants must maintain correct beliefs as their information environment evolves. In practice, evidence is scattered across heterogeneous sources that often contradict one another, new information can invalidate earlier conclusions, and user preferences surface through corrections rather than explicit instructions. Existing benchmarks largely assume static, single-authority settings and do not evaluate whether a
ClawArena: Benchmarking AI Agents in Evolving Information Environments
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cs.AI, q-bio.NC updates on arXiv.org
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Preserving Forgery Artifacts: AI-Generated Video Detection at Native Scale
arXiv:2604.04634v1 Announce Type: cross Abstract: The rapid advancement of video generation models has enabled the creation of highly realistic synthetic media, raising significant societal concerns regarding the spread of misinformation. However, current detection methods suffer from critical limitations. They rely on preprocessing operations like fixed-resolution resizing and cropping. These operations not only discard subtle, high-frequency forgery traces but also cause spatial distortion an
Preserving Forgery Artifacts: AI-Generated Video Detection at Native Scale
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cs.AI, q-bio.NC updates on arXiv.org
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TSPO: Breaking the Double Homogenization Dilemma in Multi-turn Search Policy Optimization
arXiv:2601.22776v2 Announce Type: replace Abstract: Multi-turn tool-integrated reasoning enables Large Language Models (LLMs) to solve complex tasks through iterative information retrieval. However, current reinforcement learning (RL) frameworks for search-augmented reasoning predominantly rely on sparse outcome-level rewards, leading to a "Double Homogenization Dilemma." This manifests as (1) Process homogenization, where the thinking, reasoning, and tooling involved in generation are ignored.
TSPO: Breaking the Double Homogenization Dilemma in Multi-turn Search Policy Optimization
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(Multiomics OR Omics) AND (Lung OR gastric OR Hepatocellular)
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A Data-driven Approach for Biomarker Discovery based on U-centered Distance Correlation Network: Multi-omics Warning Signals for Non-small Cell Lung Cancer
Comb Chem High Throughput Screen. 2026 Mar 27. doi: 10.2174/0113862073445368260131002109. Online ahead of print.ABSTRACTINTRODUCTION/OBJECTIVE: Lung cancer is the leading cause of cancer-related mortality worldwide, and non-small cell lung cancer (NSCLC) accounts for the majority of cases. Alterations in metabolic activities play important roles in NSCLC development, wherein related genes and metabolites interact with each other, involving multiple forms.METHODS: To comprehensively understand th
A Data-driven Approach for Biomarker Discovery based on U-centered Distance Correlation Network: Multi-omics Warning Signals for Non-small Cell Lung Cancer
Comb Chem High Throughput Screen. 2026 Mar 27. doi: 10.2174/0113862073445368260131002109. Online ahead of print.
ABSTRACT
INTRODUCTION/OBJECTIVE: Lung cancer is the leading cause of cancer-related mortality worldwide, and non-small cell lung cancer (NSCLC) accounts for the majority of cases. Alterations in metabolic activities play important roles in NSCLC development, wherein related genes and metabolites interact with each other, involving multiple forms.
METHODS: To comprehensively understand the pathogenic mechanisms and improve the performance of clinical early, precise diagnosis, this study proposed a data-driven approach for biomarker discovery based on U-centered distance correlation network (DCN) to investigate NSCLC metabolism-related reactions. In DCN, changes in molecular relationships during NSCLC initiation and progression are measured using the t-statistics of U-centered distance correlation for network construction, in which prospective warning signals representing NSCLC onset can be identified without human intervention. Additionally, the network construction criterion in DCN can precisely and effectively capture both linear and nonlinear molecular relationships in simple and biologically relevant manners.
RESULTS: DCN was successfully employed to analyze NSCLC metabolism-related metabolomics and genomics datasets. Statistical analyses confirmed that compared with other algorithms, the gene and metabolite biomarker panels identified by DCN provided more reliable diagnostic capabilities for clinical NSCLC detection. Biological analyses revealed that disturbed energy metabolism and lipid metabolism occurred during tumor cell proliferation and growth in NSCLC patients.
DISCUSSION: The gene ASPA and metabolite aspartic acid were significantly decreased in NSCLC samples, suggesting that the corresponding amino acid metabolic activities were intricately linked to NSCLC progression.
CONCLUSION: These findings demonstrated that DCN can further facilitate NSCLC studies to improve clinical outcomes in patients.
PMID:41937706 | DOI:10.2174/0113862073445368260131002109
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Omics In Lung
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A Data-driven Approach for Biomarker Discovery based on U-centered Distance Correlation Network: Multi-omics Warning Signals for Non-small Cell Lung Cancer
Comb Chem High Throughput Screen. 2026 Mar 27. doi: 10.2174/0113862073445368260131002109. Online ahead of print.ABSTRACTINTRODUCTION/OBJECTIVE: Lung cancer is the leading cause of cancer-related mortality worldwide, and non-small cell lung cancer (NSCLC) accounts for the majority of cases. Alterations in metabolic activities play important roles in NSCLC development, wherein related genes and metabolites interact with each other, involving multiple forms.METHODS: To comprehensively understand th
A Data-driven Approach for Biomarker Discovery based on U-centered Distance Correlation Network: Multi-omics Warning Signals for Non-small Cell Lung Cancer
Comb Chem High Throughput Screen. 2026 Mar 27. doi: 10.2174/0113862073445368260131002109. Online ahead of print.
ABSTRACT
INTRODUCTION/OBJECTIVE: Lung cancer is the leading cause of cancer-related mortality worldwide, and non-small cell lung cancer (NSCLC) accounts for the majority of cases. Alterations in metabolic activities play important roles in NSCLC development, wherein related genes and metabolites interact with each other, involving multiple forms.
METHODS: To comprehensively understand the pathogenic mechanisms and improve the performance of clinical early, precise diagnosis, this study proposed a data-driven approach for biomarker discovery based on U-centered distance correlation network (DCN) to investigate NSCLC metabolism-related reactions. In DCN, changes in molecular relationships during NSCLC initiation and progression are measured using the t-statistics of U-centered distance correlation for network construction, in which prospective warning signals representing NSCLC onset can be identified without human intervention. Additionally, the network construction criterion in DCN can precisely and effectively capture both linear and nonlinear molecular relationships in simple and biologically relevant manners.
RESULTS: DCN was successfully employed to analyze NSCLC metabolism-related metabolomics and genomics datasets. Statistical analyses confirmed that compared with other algorithms, the gene and metabolite biomarker panels identified by DCN provided more reliable diagnostic capabilities for clinical NSCLC detection. Biological analyses revealed that disturbed energy metabolism and lipid metabolism occurred during tumor cell proliferation and growth in NSCLC patients.
DISCUSSION: The gene ASPA and metabolite aspartic acid were significantly decreased in NSCLC samples, suggesting that the corresponding amino acid metabolic activities were intricately linked to NSCLC progression.
CONCLUSION: These findings demonstrated that DCN can further facilitate NSCLC studies to improve clinical outcomes in patients.
PMID:41937706 | DOI:10.2174/0113862073445368260131002109
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cs.AI, q-bio.NC updates on arXiv.org
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DriveDreamer-Policy: A Geometry-Grounded World-Action Model for Unified Generation and Planning
arXiv:2604.01765v1 Announce Type: cross Abstract: Recently, world-action models (WAM) have emerged to bridge vision-language-action (VLA) models and world models, unifying their reasoning and instruction-following capabilities and spatio-temporal world modeling. However, existing WAM approaches often focus on modeling 2D appearance or latent representations, with limited geometric grounding-an essential element for embodied systems operating in the physical world. We present DriveDreamer-Policy
DriveDreamer-Policy: A Geometry-Grounded World-Action Model for Unified Generation and Planning
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cs.AI, q-bio.NC updates on arXiv.org
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Beyond Matching to Tiles: Bridging Unaligned Aerial and Satellite Views for Vision-Only UAV Navigation
arXiv:2603.22153v2 Announce Type: replace-cross Abstract: Recent advances in cross-view geo-localization (CVGL) methods have shown strong potential for supporting unmanned aerial vehicle (UAV) navigation in GNSS-denied environments. However, existing work predominantly focuses on matching UAV views to onboard map tiles, which introduces an inherent trade-off between accuracy and storage overhead, and overlooks the importance of the UAV's heading during navigation. Moreover, the substantial disc
Beyond Matching to Tiles: Bridging Unaligned Aerial and Satellite Views for Vision-Only UAV Navigation
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cs.AI, q-bio.NC updates on arXiv.org
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DrivingGen: A Comprehensive Benchmark for Generative Video World Models in Autonomous Driving
arXiv:2601.01528v2 Announce Type: replace-cross Abstract: Video generation models, as one form of world models, have emerged as one of the most exciting frontiers in AI, promising agents the ability to imagine the future by modeling the temporal evolution of complex scenes. In autonomous driving, this vision gives rise to driving world models: generative simulators that imagine ego and agent futures, enabling scalable simulation, safe testing of corner cases, and rich synthetic data generation.