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Non-Invasive Reconstruction of Intracranial EEG Across the Deep Temporal Lobe from Scalp EEG based on Conditional Normalizing Flow

arXiv:2603.03354v1 Announce Type: new Abstract: Although obtaining deep brain activity from non-invasive scalp electroencephalography (sEEG) is crucial for neuroscience and clinical diagnosis, directly generating high-fidelity intracranial electroencephalography (iEEG) signals remains a largely unexplored field, limiting our understanding of deep brain dynamics. Current research primarily focuses on traditional signal processing or source localization methods, which struggle to capture the complex waveforms and random characteristics of iEEG. To address this critical challenge, this paper introduces NeuroFlowNet, a novel cross-modal generative framework whose core contribution lies in the first-ever reconstruction of iEEG signals from the entire deep temporal lobe region using sEEG signals. NeuroFlowNet is built on Conditional Normalizing Flow (CNF), which directly models complex conditional probability distributions through reversible transformations, thereby explicitly capturing the randomness of brain signals and fundamentally avoiding the pattern collapse issues common in existing generative models. Additionally, the model integrates a multi-scale architecture and self-attention mechanisms to robustly capture fine-grained temporal details and long-range dependencies. Validation results on a publicly available synchronized sEEG-iEEG dataset demonstrate NeuroFlowNet's effectiveness in terms of temporal waveform fidelity, spectral feature reproduction, and functional connectivity restoration. This study establishes a more reliable and scalable new paradigm for non-invasive analysis of deep brain dynamics. The code of this study is available in https://github.com/hdy6438/NeuroFlowNet

Specification-Driven Generation and Evaluation of Discrete-Event World Models via the DEVS Formalism

arXiv:2603.03784v1 Announce Type: new Abstract: World models are essential for planning and evaluation in agentic systems, yet existing approaches lie at two extremes: hand-engineered simulators that offer consistency and reproducibility but are costly to adapt, and implicit neural models that are flexible but difficult to constrain, verify, and debug over long horizons. We seek a principled middle ground that combines the reliability of explicit simulators with the flexibility of learned models, allowing world models to be adapted during online execution. By targeting a broad class of environments whose dynamics are governed by the ordering, timing, and causality of discrete events, such as queueing and service operations, embodied task planning, and message-mediated multi-agent coordination, we advocate explicit, executable discrete-event world models synthesized directly from natural-language specifications. Our approach adopts the DEVS formalism and introduces a staged LLM-based generation pipeline that separates structural inference of component interactions from component-level event and timing logic. To evaluate generated models without a unique ground truth, simulators emit structured event traces that are validated against specification-derived temporal and semantic constraints, enabling reproducible verification and localized diagnostics. Together, these contributions produce world models that are consistent over long-horizon rollouts, verifiable from observable behavior, and efficient to synthesize on demand during online execution.

Towards Self-Robust LLMs: Intrinsic Prompt Noise Resistance via CoIPO

arXiv:2603.03314v1 Announce Type: cross Abstract: Large language models (LLMs) have demonstrated remarkable and steadily improving performance across a wide range of tasks. However, LLM performance may be highly sensitive to prompt variations especially in scenarios with limited openness or strict output formatting requirements, indicating insufficient robustness. In real-world applications, user prompts provided to LLMs often contain imperfections, which may undermine the quality of the model's responses. To address this issue, previous work has primarily focused on preprocessing prompts, employing external tools or even LLMs to refine prompt formulations in advance. However, these approaches overlook the intrinsic robustness of LLMs, and their reliance on external components introduces additional computational overhead and uncertainty. In this work, we propose a Contrastive Learning-based Inverse Direct Preference Optimization (CoIPO) method that minimizes the discrepancy between the label-aligned logits produced by the model under a clean prompt and its noisy counterpart, and conduct a detailed analysis using mutual information theory. We augment the FLAN dataset by constructing paired prompts, each consisting of a clean prompt and its corresponding noisy version for training. Additionally, to evaluate the effectiveness, we develop NoisyPromptBench, a benchmark enhanced and derived from the existing PromptBench. Experimental results conducted on NoisyPromptBench demonstrate that our proposed method achieves a significant improvement in average accuracy over the current state-of-the-art approaches. The source code of CoIPO, pair-wise FLAN datasets, and NoisyPromptBench have already been released on https://github.com/vegetable-yx/CoIPO.

AOI: Turning Failed Trajectories into Training Signals for Autonomous Cloud Diagnosis

arXiv:2603.03378v1 Announce Type: cross Abstract: Large language model (LLM) agents offer a promising data-driven approach to automating Site Reliability Engineering (SRE), yet their enterprise deployment is constrained by three challenges: restricted access to proprietary data, unsafe action execution under permission-governed environments, and the inability of closed systems to improve from failures. We present AOI (Autonomous Operations Intelligence), a trainable multi-agent framework formulating automated operations as a structured trajectory learning problem under security constraints. Our approach integrates three key components. First, a trainable diagnostic system applies Group Relative Policy Optimization (GRPO) to distill expert-level knowledge into locally deployed open-source models, enabling preference-based learning without exposing sensitive data. Second, a read-write separated execution architecture decomposes operational trajectories into observation, reasoning, and action phases, allowing safe learning while preventing unauthorized state mutation. Third, a Failure Trajectory Closed-Loop Evolver mines unsuccessful trajectories and converts them into corrective supervision signals, enabling continual data augmentation. Evaluated on the AIOpsLab benchmark, our contributions yield cumulative gains. (1) The AOI runtime alone achieves 66.3% best@5 success on all 86 tasks, outperforming the prior state-of-the-art (41.9%) by 24.4 points. (2) Adding Observer GRPO training, a locally deployed 14B model reaches 42.9% avg@1 on 63 held-out tasks with unseen fault types, surpassing Claude Sonnet 4.5. (3) The Evolver converts 37 failed trajectories into diagnostic guidance, improving end-to-end avg@5 by 4.8 points while reducing variance by 35%.

Phys4D: Fine-Grained Physics-Consistent 4D Modeling from Video Diffusion

arXiv:2603.03485v1 Announce Type: cross Abstract: Recent video diffusion models have achieved impressive capabilities as large-scale generative world models. However, these models often struggle with fine-grained physical consistency, exhibiting physically implausible dynamics over time. In this work, we present \textbf{Phys4D}, a pipeline for learning physics-consistent 4D world representations from video diffusion models. Phys4D adopts \textbf{a three-stage training paradigm} that progressively lifts appearance-driven video diffusion models into physics-consistent 4D world representations. We first bootstrap robust geometry and motion representations through large-scale pseudo-supervised pretraining, establishing a foundation for 4D scene modeling. We then perform physics-grounded supervised fine-tuning using simulation-generated data, enforcing temporally consistent 4D dynamics. Finally, we apply simulation-grounded reinforcement learning to correct residual physical violations that are difficult to capture through explicit supervision. To evaluate fine-grained physical consistency beyond appearance-based metrics, we introduce a set of \textbf{4D world consistency evaluation} that probe geometric coherence, motion stability, and long-horizon physical plausibility. Experimental results demonstrate that Phys4D substantially improves fine-grained spatiotemporal and physical consistency compared to appearance-driven baselines, while maintaining strong generative performance. Our project page is available at https://sensational-brioche-7657e7.netlify.app/

PhyPrompt: RL-based Prompt Refinement for Physically Plausible Text-to-Video Generation

arXiv:2603.03505v1 Announce Type: cross Abstract: State-of-the-art text-to-video (T2V) generators frequently violate physical laws despite high visual quality. We show this stems from insufficient physical constraints in prompts rather than model limitations: manually adding physics details reliably produces physically plausible videos, but requires expertise and does not scale. We present PhyPrompt, a two-stage reinforcement learning framework that automatically refines prompts for physically realistic generation. First, we fine-tune a large language model on a physics-focused Chain-of-Thought dataset to integrate principles like object motion and force interactions while preserving user intent. Second, we apply Group Relative Policy Optimization with a dynamic reward curriculum that initially prioritizes semantic fidelity, then progressively shifts toward physical commonsense. This curriculum achieves synergistic optimization: PhyPrompt-7B reaches 40.8\% joint success on VideoPhy2 (8.6pp gain), improving physical commonsense by 11pp (55.8\% to 66.8\%) while simultaneously increasing semantic adherence by 4.4pp (43.4\% to 47.8\%). Remarkably, our curriculum exceeds single-objective training on both metrics, demonstrating compositional prompt discovery beyond conventional multi-objective trade-offs. PhyPrompt outperforms GPT-4o (+3.8\% joint) and DeepSeek-V3 (+2.2\%, 100$\times$ larger) using only 7B parameters. The approach transfers zero-shot across diverse T2V architectures (Lavie, VideoCrafter2, CogVideoX-5B) with up to 16.8\% improvement, establishing that domain-specialized reinforcement learning with compositional curricula surpasses general-purpose scaling for physics-aware generation.

PROSPECT: Unified Streaming Vision-Language Navigation via Semantic--Spatial Fusion and Latent Predictive Representation

arXiv:2603.03739v1 Announce Type: cross Abstract: Multimodal large language models (MLLMs) have advanced zero-shot end-to-end Vision-Language Navigation (VLN), yet robust navigation requires not only semantic understanding but also predictive modeling of environment dynamics and spatial structure. We propose PROSPECT, a unified streaming navigation agent that couples a streaming Vision-Language-Action (VLA) policy with latent predictive representation learning. PROSPECT uses CUT3R as a streaming 3D foundation spatial encoder to produce long-context, absolute-scale spatial features, and fuses them with SigLIP semantic features via cross-attention. During training, we introduce learnable stream query tokens that query the streaming context and predict next-step 2D and 3D latent features (rather than pixels or explicit modalities), supervised in the latent spaces of frozen SigLIP and CUT3R teachers. The predictive branch shapes internal representations without inference overhead. Experiments on VLN-CE benchmarks and real-robot deployment demonstrate state-of-the-art performance and improved long-horizon robustness under diverse lighting. We will release code for the community soon.

T2S-Bench & Structure-of-Thought: Benchmarking and Prompting Comprehensive Text-to-Structure Reasoning

arXiv:2603.03790v1 Announce Type: cross Abstract: Think about how human handles complex reading tasks: marking key points, inferring their relationships, and structuring information to guide understanding and responses. Likewise, can a large language model benefit from text structure to enhance text-processing performance? To explore it, in this work, we first introduce Structure of Thought (SoT), a prompting technique that explicitly guides models to construct intermediate text structures, consistently boosting performance across eight tasks and three model families. Building upon this insight, we present T2S-Bench, the first benchmark designed to evaluate and improve text-to-structure capabilities of models. T2S-Bench includes 1.8K samples across 6 scientific domains and 32 structural types, rigorously constructed to ensure accuracy, fairness, and quality. Evaluation on 45 mainstream models reveals substantial improvement potential: the average accuracy on the multi-hop reasoning task is only 52.1%, and even the most advanced model achieves 58.1% node accuracy in end-to-end extraction. Furthermore, on Qwen2.5-7B-Instruct, SoT alone yields an average +5.7% improvement across eight diverse text-processing tasks, and fine-tuning on T2S-Bench further increases this gain to +8.6%. These results highlight the value of explicit text structuring and the complementary contributions of SoT and T2S-Bench. Dataset and eval code have been released at https://t2s-bench.github.io/T2S-Bench-Page/.

Pretrained Vision-Language-Action Models are Surprisingly Resistant to Forgetting in Continual Learning

arXiv:2603.03818v1 Announce Type: cross Abstract: Continual learning is a long-standing challenge in robot policy learning, where a policy must acquire new skills over time without catastrophically forgetting previously learned ones. While prior work has extensively studied continual learning in relatively small behavior cloning (BC) policy models trained from scratch, its behavior in modern large-scale pretrained Vision-Language-Action (VLA) models remains underexplored. In this work, we found that pretrained VLAs are remarkably resistant to forgetting compared with smaller policy models trained from scratch. Simple Experience Replay (ER) works surprisingly well on VLAs, sometimes achieving zero forgetting even with a small replay data size. Our analysis reveals that pretraining plays a critical role in downstream continual learning performance: large pretrained models mitigate forgetting with a small replay buffer size while maintaining strong forward learning capabilities. Furthermore, we found that VLAs can retain relevant knowledge from prior tasks despite performance degradation during learning new tasks. This knowledge retention enables rapid recovery of seemingly forgotten skills through finetuning. Together, these insights imply that large-scale pretraining fundamentally changes the dynamics of continual learning, enabling models to continually acquire new skills over time with simple replay. Code and more information can be found at https://ut-austin-rpl.github.io/continual-vla

PlaneCycle: Training-Free 2D-to-3D Lifting of Foundation Models Without Adapters

arXiv:2603.04165v1 Announce Type: cross Abstract: Large-scale 2D foundation models exhibit strong transferable representations, yet extending them to 3D volumetric data typically requires retraining, adapters, or architectural redesign. We introduce PlaneCycle, a training-free, adapter-free operator for architecture-agnostic 2D-to-3D lifting of foundation models. PlaneCycle reuses the original pretrained 2D backbone by cyclically distributing spatial aggregation across orthogonal HW, DW, and DH planes throughout network depth, enabling progressive 3D fusion while preserving pretrained inductive biases. The method introduces no additional parameters and is applicable to arbitrary 2D networks. Using pretrained DINOv3 models, we evaluate PlaneCycle on six 3D classification and three 3D segmentation benchmarks. Without any training, the lifted models exhibit intrinsic 3D fusion capability and, under linear probing, outperform slice-wise 2D baselines and strong 3D counterparts, approaching the performance of fully trained models. With full fine-tuning, PlaneCycle matches standard 3D architectures, highlighting its potential as a seamless and practical 2D-to-3D lifting operator. These results demonstrate that 3D capability can be unlocked from pretrained 2D foundation models without structural modification or retraining. Code is available at https://github.com/HINTLab/PlaneCycle.

IPD: Boosting Sequential Policy with Imaginary Planning Distillation in Offline Reinforcement Learning

arXiv:2603.04289v1 Announce Type: cross Abstract: Decision transformer based sequential policies have emerged as a powerful paradigm in offline reinforcement learning (RL), yet their efficacy remains constrained by the quality of static datasets and inherent architectural limitations. Specifically, these models often struggle to effectively integrate suboptimal experiences and fail to explicitly plan for an optimal policy. To bridge this gap, we propose \textbf{Imaginary Planning Distillation (IPD)}, a novel framework that seamlessly incorporates offline planning into data generation, supervised training, and online inference. Our framework first learns a world model equipped with uncertainty measures and a quasi-optimal value function from the offline data. These components are utilized to identify suboptimal trajectories and augment them with reliable, imagined optimal rollouts generated via Model Predictive Control (MPC). A Transformer-based sequential policy is then trained on this enriched dataset, complemented by a value-guided objective that promotes the distillation of the optimal policy. By replacing the conventional, manually-tuned return-to-go with the learned quasi-optimal value function, IPD improves both decision-making stability and performance during inference. Empirical evaluations on the D4RL benchmark demonstrate that IPD significantly outperforms several state-of-the-art value-based and transformer-based offline RL methods across diverse tasks.

Offline-to-Online Multi-Agent Reinforcement Learning with Offline Value Function Memory and Sequential Exploration

arXiv:2410.19450v3 Announce Type: replace Abstract: Offline-to-Online Reinforcement Learning has emerged as a powerful paradigm, leveraging offline data for initialization and online fine-tuning to enhance both sample efficiency and performance. However, most existing research has focused on single-agent settings, with limited exploration of the multi-agent extension, i.e., Offline-to-Online Multi-Agent Reinforcement Learning (O2O MARL). In O2O MARL, two critical challenges become more prominent as the number of agents increases: (i) the risk of unlearning pre-trained Q-values due to distributional shifts during the transition from offline-to-online phases, and (ii) the difficulty of efficient exploration in the large joint state-action space. To tackle these challenges, we propose a novel O2O MARL framework called Offline Value Function Memory with Sequential Exploration (OVMSE). First, we introduce the Offline Value Function Memory (OVM) mechanism to compute target Q-values, preserving knowledge gained during offline training, ensuring smoother transitions, and enabling efficient fine-tuning. Second, we propose a decentralized Sequential Exploration (SE) strategy tailored for O2O MARL, which effectively utilizes the pre-trained offline policy for exploration, thereby significantly reducing the joint state-action space to be explored. Extensive experiments on the StarCraft Multi-Agent Challenge (SMAC) demonstrate that OVMSE significantly outperforms existing baselines, achieving superior sample efficiency and overall performance.

To Think or Not To Think, That is The Question for Large Reasoning Models in Theory of Mind Tasks

arXiv:2602.10625v3 Announce Type: replace Abstract: Theory of Mind (ToM) assesses whether models can infer hidden mental states such as beliefs, desires, and intentions, which is essential for natural social interaction. Although recent progress in Large Reasoning Models (LRMs) has boosted step-by-step inference in mathematics and coding, it is still underexplored whether this benefit transfers to socio-cognitive skills. We present a systematic study of nine advanced Large Language Models (LLMs), comparing reasoning models with non-reasoning models on three representative ToM benchmarks. The results show that reasoning models do not consistently outperform non-reasoning models and sometimes perform worse. A fine-grained analysis reveals three insights. First, slow thinking collapses: accuracy significantly drops as responses grow longer, and larger reasoning budgets hurt performance. Second, moderate and adaptive reasoning benefits performance: constraining reasoning length mitigates failure, while distinct success patterns demonstrate the necessity of dynamic adaptation. Third, option matching shortcut: when multiple choice options are removed, reasoning models improve markedly, indicating reliance on option matching rather than genuine deduction. We also design two intervention approaches: Slow-to-Fast (S2F) adaptive reasoning and Think-to-Match (T2M) shortcut prevention to further verify and mitigate the problems. With all results, our study highlights the advancement of LRMs in formal reasoning (e.g., math, code) cannot be fully transferred to ToM, a typical task in social reasoning. We conclude that achieving robust ToM requires developing unique capabilities beyond existing reasoning methods.

Difficult Examples Hurt Unsupervised Contrastive Learning: A Theoretical Perspective

arXiv:2501.01317v2 Announce Type: replace-cross Abstract: Unsupervised contrastive learning has shown significant performance improvements in recent years, often approaching or even rivaling supervised learning in various tasks. However, its learning mechanism is fundamentally different from supervised learning. Previous works have shown that difficult examples (well-recognized in supervised learning as examples around the decision boundary), which are essential in supervised learning, contribute minimally in unsupervised settings. In this paper, perhaps surprisingly, we find that the direct removal of difficult examples, although reduces the sample size, can boost the downstream classification performance of contrastive learning. To uncover the reasons behind this, we develop a theoretical framework modeling the similarity between different pairs of samples. Guided by this framework, we conduct a thorough theoretical analysis revealing that the presence of difficult examples negatively affects the generalization of contrastive learning. Furthermore, we demonstrate that the removal of these examples, and techniques such as margin tuning and temperature scaling can enhance its generalization bounds, thereby improving performance. Empirically, we propose a simple and efficient mechanism for selecting difficult examples and validate the effectiveness of the aforementioned methods, which substantiates the reliability of our proposed theoretical framework.

Preference Leakage: A Contamination Problem in LLM-as-a-judge

arXiv:2502.01534v3 Announce Type: replace-cross Abstract: Large Language Models (LLMs) as judges and LLM-based data synthesis have emerged as two fundamental LLM-driven data annotation methods in model development. While their combination significantly enhances the efficiency of model training and evaluation, little attention has been given to the potential contamination brought by this new model development paradigm. In this work, we expose preference leakage, a contamination problem in LLM-as-a-judge caused by the relatedness between the synthetic data generators and LLM-based evaluators. To study this issue, we first define three common relatednesses between the data generator LLM and the judge LLM: being the same model, having an inheritance relationship, and belonging to the same model family. Through extensive experiments, we empirically confirm the bias of judges towards their related student models caused by preference leakage across multiple LLM baselines and benchmarks. Further analysis suggests that preference leakage is a pervasive and real-world problem that is harder to detect compared to previously identified biases in LLM-as-a-judge scenarios. All of these findings imply that preference leakage is a widespread and challenging problem in the area of LLM-as-a-judge. We release all codes and data at: https://github.com/David-Li0406/Preference-Leakage.

Towards Personalized Deep Research: Benchmarks and Evaluations

arXiv:2509.25106v3 Announce Type: replace-cross Abstract: Deep Research Agents (DRAs) can autonomously conduct complex investigations and generate comprehensive reports, demonstrating strong real-world potential. However, existing evaluations mostly rely on close-ended benchmarks, while open-ended deep research benchmarks remain scarce and typically neglect personalized scenarios. To bridge this gap, we introduce Personalized Deep Research Bench (PDR-Bench), the first benchmark for evaluating personalization in DRAs. It pairs 50 diverse research tasks across 10 domains with 25 authentic user profiles that combine structured persona attributes with dynamic real-world contexts, yielding 250 realistic user-task queries. To assess system performance, we propose the PQR Evaluation Framework, which jointly measures Personalization Alignment, Content Quality, and Factual Reliability. Our experiments on a range of systems highlight current capabilities and limitations in handling personalized deep research. This work establishes a rigorous foundation for developing and evaluating the next generation of truly personalized AI research assistants.

Vision-Zero: Scalable VLM Self-Improvement via Strategic Gamified Self-Play

arXiv:2509.25541v2 Announce Type: replace-cross Abstract: Although reinforcement learning (RL) has emerged as a promising approach for improving vision-language models (VLMs) and multimodal large language models (MLLMs), current methods rely heavily on manually curated datasets and costly human verification, which limits scalable self-improvement in multimodal systems. To address this challenge, we propose Vision-Zero, a label-free, domain-agnostic multi-agent self-play framework for self-evolving VLMs through competitive visual games generated from arbitrary image inputs. Specifically, Vision-Zero encompasses three main attributes: (1) Strategic Self-Play Framework: Vision-Zero trains VLMs in "Who Is the Spy"-style games, where the models engage in strategic reasoning and actions across multiple roles. Through interactive gameplay, models autonomously generate their training data without human annotation. (2) Gameplay from Arbitrary Images: Unlike existing gamified frameworks, Vision-Zero can generate games from arbitrary images, thereby enhancing the model's reasoning ability across diverse domains and showing strong generalization to different tasks. We demonstrate this versatility using three distinct types of image datasets: CLEVR-based synthetic scenes, charts, and real-world images. (3) Sustainable Performance Gain: We introduce Iterative Self-Play Policy Optimization (Iterative-SPO), a novel training algorithm that alternates between Self-Play and reinforcement learning with verifiable rewards (RLVR), mitigating the performance plateau often seen in self-play-only training and achieving sustained long-term improvements. Despite using label-free data, Vision-Zero achieves state-of-the-art performance on reasoning, chart question answering, and vision-centric understanding tasks, surpassing other annotation-based methods. Models and code have been released at https://github.com/wangqinsi1/Vision-Zero.

EnECG: Efficient Ensemble Learning for Electrocardiogram Multi-task Foundation Model

arXiv:2511.22935v2 Announce Type: replace-cross Abstract: Electrocardiogram (ECG) analysis plays a vital role in the early detection, monitoring, and management of various cardiovascular conditions. While existing models have achieved notable success in ECG interpretation, they fail to leverage the interrelated nature of various cardiac abnormalities. Conversely, developing a specific model capable of extracting all relevant features for multiple ECG tasks remains a significant challenge. Large-scale foundation models, though powerful, are not typically pretrained on ECG data, making full re-training or fine-tuning computationally expensive. To address these challenges, we propose EnECG(Mixture of Experts-based Ensemble Learning for ECG Multi-tasks), an ensemble-based framework that integrates multiple specialized foundation models, each excelling in different aspects of ECG interpretation. Instead of relying on a single model or single task, EnECG leverages the strengths of multiple specialized models to tackle a variety of ECG-based tasks. To mitigate the high computational cost of full re-training or fine-tuning, we introduce a lightweight adaptation strategy: attaching dedicated output layers to each foundation model and applying Low-Rank Adaptation (LoRA) only to these newly added parameters. We then adopt a Mixture of Experts (MoE) mechanism to learn ensemble weights, effectively combining the complementary expertise of individual models. Our experimental results demonstrate that by minimizing the scope of fine-tuning, EnECG can help reduce computational and memory costs while maintaining the strong representational power of foundation models. This framework not only enhances feature extraction and predictive performance but also ensures practical efficiency for real-world clinical applications. The code is available at https://github.com/yuhaoxu99/EnECG.git.

ITO: Images and Texts as One via Synergizing Multiple Alignment and Training-Time Fusion

arXiv:2603.02767v2 Announce Type: replace-cross Abstract: Image-text contrastive pretraining has become a dominant paradigm for visual representation learning, yet existing methods often yield representations that remain partially organized by modality. We propose ITO, a framework addressing this limitation through two synergistic mechanisms. Multimodal multiple alignment enriches supervision by mining diverse image-text correspondences, while a lightweight training-time multimodal fusion module enforces structured cross-modal interaction. Crucially, the fusion module is discarded at inference, preserving the efficiency of standard dual-encoder architectures. Extensive experiments show that ITO consistently outperforms strong baselines across classification, retrieval, and multimodal benchmarks. Our analysis reveals that while multiple alignment drives discriminative power, training-time fusion acts as a critical structural regularizer -- eliminating the modality gap and stabilizing training dynamics to prevent the early saturation often observed in aggressive contrastive learning.

RxnNano:Training Compact LLMs for Chemical Reaction and Retrosynthesis Prediction via Hierarchical Curriculum Learning

arXiv:2603.02215v1 Announce Type: cross Abstract: Chemical reaction prediction is pivotal for accelerating drug discovery and synthesis planning. Despite advances in data-driven models, current approaches are hindered by an overemphasis on parameter and dataset scaling. Some methods coupled with evaluation techniques that bypass fundamental challenges in reaction representation and fail to capture deep chemical intuition like reaction common sense and {topological atom mapping logic}. We argue that the core challenge lies in instilling these knowledge into the models. To this end, we propose a unified framework that prioritizes chemical understanding over scale through three key innovations: (1) a {Latent Chemical Consistency} objective that models reactions as movements on a continuous chemical manifold, ensuring reversible and physically plausible transformations; (2) a {Hierarchical Cognitive Curriculum} that trains the model through progressive stages, from syntax mastery to semantic reasoning, building robust chemical intuition; (3) {Atom-Map Permutation Invariance (AMPI)}, which force the model to learn invariant relational topology and balance multi-task learning. (4)and structured plan-based reasoning to improve the performance of the LLMs. Our compact {0.5B-parameter model}, \textbf{RxnNano} significantly outperforms fine-tuned LLMs ten times larger (>7B) and all the domain baselines, achieving a 23.5\% Top-1 accuracy improvement on rigorous benchmarks without test-time augmentation. https://github.com/rlisml/RxnNano.
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