arXiv:2603.07940v1 Announce Type: cross Abstract: Modern science is reaching a critical inflection point. Instruments across disciplines, from particle physics and astronomy to genomics and climate modeling, now produce data of such scale, diversity, and interdependence that traditional analytical methods can no longer keep pace. This growing imbalance between data generation and data understanding signals the need for a new scientific paradigm. We propose that intelligent, human-supervised AI agents operating over deep-learning algorithms, represent the next evolution of the scientific method. Built upon large language models and multimodal learning, these agents can interpret scientific intent, design and execute analytical workflows, and ensure traceability through domain-specific languages that preserve human oversight and accountability. Particle physics, a historic incubator of computational innovation, offers the ideal testbed for this transition. At the Institute of High Energy Physics of the Chinese Academy of Sciences, the Dr. Sai system embodies this vision, a multi-agent reasoning framework deployed within collider research at the CEPC. This emerging approach does not replace human scientists but extends their cognitive reach, enabling discovery to scale with complexity and redefining how knowledge itself is produced in the age of intelligent machines. The significance of this paradigm transcends particle physics, offering a blueprint for all data-driven sciences facing the same complexity ceiling.

arXiv:2511.18999v2 Announce Type: replace-cross Abstract: The current KM3NeT/ORCA neutrino telescope, still under construction, has not yet reached its full potential in neutrino reconstruction capability. When training any deep learning model, no explicit information about the physics or the detector is provided, thus they remain unknown to the model. This study leverages the strengths of transformers by incorporating attention masks inspired by the physics and detector design, making the model understand both the telescope design and the neutrino physics measured on it. The study also shows the efficacy of transformers on retaining valuable information between detectors when doing fine-tuning from one configurations to another.