The startup also announced a $5 million "rescue fund" to help credit unions ditch legacy software for its AI-native platform.

arXiv:2603.12878v1 Announce Type: new Abstract: The synchronized activity of neuronal populations can lead to pathological over-synchronization in conditions such as epilepsy and Parkinson disease. Such states can be desynchronized by brief electrical pulses. But when the underlying oscillating system is not known, as in most practical applications, to determine the specific times and intensities of pulses used for desynchronizaton is a difficult inverse problem. Here we propose a desynchronization scheme for neuronal models of bi-variate neural activity, with possible applications in the medical setting. Our main argument is the existence of a peculiar point in the phase space of the system, the centroid, that is both easy to calculate and robust under changes in the coupling constant. This important target point can be used in a control procedure because it lies in the region of minimal return times of the system.

arXiv:2603.12564v1 Announce Type: cross Abstract: Tool-augmented LLM agents increasingly serve as multi-turn advisors in high-stakes domains, yet their evaluation relies on ranking-quality metrics that measure what is recommended but not whether it is safe for the user. We introduce a paired-trajectory protocol that replays real financial dialogues under clean and contaminated tool-output conditions across seven LLMs (7B to frontier) and decomposes divergence into information-channel and memory-channel mechanisms. Across the seven models tested, we consistently observe the evaluation-blindness pattern: recommendation quality is largely preserved under contamination (utility preservation ratio approximately 1.0) while risk-inappropriate products appear in 65-93% of turns, a systematic safety failure poorly reflected by standard NDCG. Safety violations are predominantly information-channel-driven, emerge at the first contaminated turn, and persist without self-correction over 23-step trajectories; no agent across 1,563 contaminated turns explicitly questions tool-data reliability. Even narrative-only corruption (biased headlines, no numerical manipulation) induces significant drift while completely evading consistency monitors. A safety-penalized NDCG variant (sNDCG) reduces preservation ratios to 0.51-0.74, indicating that much of the evaluation gap becomes visible once safety is explicitly measured. These results motivate considering trajectory-level safety monitoring, beyond single-turn quality, for deployed multi-turn agents in high-stakes settings.

arXiv:2603.13083v1 Announce Type: cross Abstract: Providing timely and individualised feedback on handwritten student work is highly beneficial for learning but difficult to achieve at scale. This challenge has become more pressing as generative AI undermines the reliability of take-home assessments, shifting emphasis toward supervised, in-class evaluation. We present a scalable, end-to-end workflow for LLM-assisted grading of short, pen-and-paper assessments. The workflow spans (1) constructing solution keys, (2) developing detailed rubric-style grading keys used to guide the LLM, and (3) a grading procedure that combines automated scanning and anonymisation, multi-pass LLM scoring, automated consistency checks, and mandatory human verification. We deploy the system in two undergraduate mathematics courses using six low-stakes in-class tests. Empirically, LLM assistance reduces grading time by approximately 23% while achieving agreement comparable to, and in several cases tighter than, fully manual grading. Occasional model errors occur but are effectively contained by the hybrid design. Overall, our results show that carefully embedded human-in-the-loop LLM grading can substantially reduce workload while maintaining fairness and accuracy.

arXiv:2603.13177v1 Announce Type: cross Abstract: The dynamics of Saturn's satellite system offer a rich framework for studying orbital stability and resonance interactions. Traditional methods for analysing such systems, including Fourier analysis and stability metrics, struggle with the scale and complexity of modern datasets. This study introduces a machine learning-based pipeline for clustering approximately 22,300 simulated satellite orbits, addressing these challenges with advanced feature extraction and dimensionality reduction techniques. The key to this approach is using MiniRocket, which efficiently transforms 400 timesteps into a 9,996-dimensional feature space, capturing intricate temporal patterns. Additional automated feature extraction and dimensionality reduction techniques refine the data, enabling robust clustering analysis. This pipeline reveals stability regions, resonance structures, and other key behaviours in Saturn's satellite system, providing new insights into their long-term dynamical evolution. By integrating computational tools with traditional celestial mechanics techniques, this study offers a scalable and interpretable methodology for analysing large-scale orbital datasets and advancing the exploration of planetary dynamics.

arXiv:2502.21123v5 Announce Type: replace-cross Abstract: Ensuring trustworthiness in machine learning (ML) systems is crucial as they become increasingly embedded in high-stakes domains. This paper advocates for integrating causal methods into machine learning to navigate the trade-offs among key principles of trustworthy ML, including fairness, privacy, robustness, accuracy, and explainability. While these objectives should ideally be satisfied simultaneously, they are often addressed in isolation, leading to conflicts and suboptimal solutions. Drawing on existing applications of causality in ML that successfully align goals such as fairness and accuracy or privacy and robustness, this paper argues that a causal approach is essential for balancing multiple competing objectives in both trustworthy ML and foundation models. Beyond highlighting these trade-offs, we examine how causality can be practically integrated into ML and foundation models, offering solutions to enhance their reliability and interpretability. Finally, we discuss the challenges, limitations, and opportunities in adopting causal frameworks, paving the way for more accountable and ethically sound AI systems.

arXiv:2601.10436v2 Announce Type: replace-cross Abstract: Ontological Knowledge Bases (OKBs) play a vital role in structuring domain-specific knowledge and serve as a foundation for effective knowledge management systems. However, their traditional manual development poses significant challenges related to scalability, consistency, and adaptability. Recent advancements in Generative AI, particularly Large Language Models (LLMs), offer promising solutions for automating and enhancing OKB development. This paper introduces a structured, iterative methodology leveraging LLMs to optimize knowledge acquisition, automate ontology artifact generation, and enable continuous refinement cycles. We demonstrate this approach through a detailed case study focused on developing a user context profile ontology within the vehicle sales domain. Key contributions include significantly accelerated ontology construction processes, improved ontological consistency, effective bias mitigation, and enhanced transparency in the ontology engineering process. Our findings highlight the transformative potential of integrating LLMs into ontology development, notably improving scalability, integration capabilities, and overall efficiency in knowledge management systems.

Nature Medicine, Published online: 16 March 2026; doi:10.1038/s41591-026-04306-9

In cohort 4 of the ILUSTRO trial, combination of anti-CLDN18.2 zolbetuximab plus mFOLFOX6 and nivolumab in patients with CLDN18.2-positive, HER2-negative metastatic gastric or gastroesophageal junction adenocarcinoma led to encouraging clinical efficacy, supporting the testing of this combination in a phase 3 trial.