arXiv:2603.21597v2 Announce Type: replace Abstract: Modern clinical practice increasingly depends on reasoning over heterogeneous, evolving, and incomplete patient data. Although recent advances in multimodal foundation models have improved performance on various clinical tasks, most existing models remain static, opaque, and poorly aligned with real-world clinical workflows. We present Cerebra, an interactive multi-agent AI team that coordinates specialized agents for EHR, clinical notes, and medical imaging analysis. These outputs are synthesized into a clinician-facing dashboard that combines visual analytics with a conversational interface, enabling clinicians to interrogate predictions and contextualize risk at the point of care. Cerebra supports privacy-preserving deployment by operating on structured representations and remains robust when modalities are incomplete. We evaluated Cerebra using a massive multi-institutional dataset spanning 3 million patients from four independent healthcare systems. Cerebra consistently outperformed both state-of-the-art single-modality models and large multimodal language model baselines. In dementia risk prediction, it achieved AUROCs up to 0.80, compared with 0.74 for the strongest single-modality model and 0.68 for language model baselines. For dementia diagnosis, it achieved an AUROC of 0.86, and for survival prediction, a C-index of 0.81. In a reader study with experienced physicians, Cerebra significantly improved expert performance, increasing accuracy by 17.5 percentage points in prospective dementia risk estimation. These results demonstrate Cerebra's potential for interpretable, robust decision support in clinical care.

arXiv:2507.00026v2 Announce Type: replace-cross Abstract: As large language models (LLMs) are increasingly deployed as black-box components in real-world applications, red teaming has become essential for identifying potential risks. It tests LLMs with adversarial prompts to uncover vulnerabilities and improve safety alignment. Ideally, effective red teaming should be adaptive to evolving LLM capabilities and explore a broad range of harmful topics. However, existing approaches face two limitations: 1) topic-based approaches rely on pre-collected harmful topics, limited in flexibility and adaptivity. 2) topic-free methods use reinforcement learning (RL), but they lack an explicit reward signal for exploration and tend to over-optimize a narrow objective, reducing topic diversity. To address these limitations, we propose RedTopic, a novel red teaming framework that generates topic-diverse adversarial prompts through a contextualized generation pipeline, an aggregate reward design, and a multi-objective RL training loop. Experiments show that RedTopic produces more effective and diverse adversarial prompts than existing methods, with notable improvements in integrated evaluation metrics. We believe RedTopic represents a step toward more adaptive and topic-diverse red teaming for large language models.