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cs.AI, q-bio.NC updates on arXiv.org
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VTAM: Video-Tactile-Action Models for Complex Physical Interaction Beyond VLAs
arXiv:2603.23481v1 Announce Type: cross Abstract: Video-Action Models (VAMs) have emerged as a promising framework for embodied intelligence, learning implicit world dynamics from raw video streams to produce temporally consistent action predictions. Although such models demonstrate strong performance on long-horizon tasks through visual reasoning, they remain limited in contact-rich scenarios where critical interaction states are only partially observable from vision alone. In particular, fine
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cs.AI, q-bio.NC updates on arXiv.org
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Metaphor-based Jailbreak Attacks on Text-to-Image Models
arXiv:2512.10766v2 Announce Type: replace-cross Abstract: Text-to-image (T2I) models commonly incorporate defense mechanisms to prevent the generation of sensitive images. Unfortunately, recent jailbreak attacks have shown that adversarial prompts can effectively bypass these mechanisms and induce T2I models to produce sensitive content, revealing critical safety vulnerabilities. However, existing attack methods implicitly assume that the attacker knows the type of deployed defenses, which limi
Metaphor-based Jailbreak Attacks on Text-to-Image Models
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Omics in Gastric
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Mechanisms of Xinwei Tang in stress-induced gastric dysmotility: evidence from rat and In Vitro models
In Vitro Cell Dev Biol Anim. 2026 Mar 18. doi: 10.1007/s11626-026-01151-5. Online ahead of print.ABSTRACTStress is a key trigger of gastric dysmotility, partly via mitochondrial dysfunction and disordered gut-brain hormonal signaling. Xinwei Tang (XWT) is a multi-herb formula used empirically for upper gastrointestinal symptoms, but its mechanisms remain unclear. This study aimed to determine whether XWT alleviates water-immersion restraint stress (WIRS)-induced gastric dysmotility and to deline
Mechanisms of Xinwei Tang in stress-induced gastric dysmotility: evidence from rat and In Vitro models
In Vitro Cell Dev Biol Anim. 2026 Mar 18. doi: 10.1007/s11626-026-01151-5. Online ahead of print.
ABSTRACT
Stress is a key trigger of gastric dysmotility, partly via mitochondrial dysfunction and disordered gut-brain hormonal signaling. Xinwei Tang (XWT) is a multi-herb formula used empirically for upper gastrointestinal symptoms, but its mechanisms remain unclear. This study aimed to determine whether XWT alleviates water-immersion restraint stress (WIRS)-induced gastric dysmotility and to delineate underlying mitochondrial and metabolic pathways using integrated in vivo, in vitro and multi-omics approaches. Male rats underwent 7-d WIRS and received vehicle, domperidone (3 mg/kg) or XWT (3, 6, 12 g/kg). Gastric emptying, serum motilin/gastrin, oxidative stress indices and PINK1/Parkin-LC3/p62 proteins were assessed, and HβOβ-injured GES-1 cells were treated with XWT-medicated serum. Gastric antra from MOD and XWT-H rats were analyzed by RNA-seq and DIA proteomics (n = 3/group). WIRS reduced gastric emptying by roughly half and lowered motilin/gastrin, increased ROS/MDA and disrupted PINK1/Parkin-LC3/p62 profiles; XWT dose-dependently reversed these changes, with XWT-H approximating domperidone. Omics revealed XWT-associated downregulation of inflammatory/protease and acute-phase genes/proteins and enrichment of oxidative phosphorylation, tricarboxylic-acid cycle and other metabolic pathways, without global activation of canonical autophagy/mitophagy gene sets. These preclinical data indicate that XWT ameliorates stress-induced gastric dysmotility via mitochondria- and metabolism-centred protection with selective tuning of mitophagy-related proteins.
PMID:41851413 | DOI:10.1007/s11626-026-01151-5