Normal view

Received — 2 April 2026 ⏭

Nature - Issue - nature.com science feeds
Deconstruction of a spino-brain–spinal cord circuit that drives chronic pain Qian Wang · Joo Han Lee · Gregory Nachtrab · Yuan Yuan · Lei Yuan · Wei Qi · Manuel A. Mohr · Jing Xiong · Mark A. Horowitz · Xiaoke Chen
Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10296-yIn mice, a circuit between the spinal cord and various regions of the brain, centring on spinal-cord-projecting neurons in the rostral ventromedial medulla, has a key role in driving chronic pain.
1 April 2026 at 08:00

Deconstruction of a spino-brain–spinal cord circuit that drives chronic pain

Nature - Issue - nature.com science feeds

By: Qian Wang · Joo Han Lee · Gregory Nachtrab · Yuan Yuan · Lei Yuan · Wei Qi · Manuel A. Mohr · Jing Xiong · Mark A. Horowitz · Xiaoke Chen

1 April 2026 at 08:00

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10296-y

In mice, a circuit between the spinal cord and various regions of the brain, centring on spinal-cord-projecting neurons in the rostral ventromedial medulla, has a key role in driving chronic pain.