arXiv:2604.01538v1 Announce Type: cross Abstract: Large language models have been adopted in the medical domain for clinical documentation to reduce clinician burden. However, studies have reported that LLMs often "forget" a significant amount of instruction-following ability when fine-tuned using a task-specific medical dataset, a critical challenge in adopting general-purpose LLMs for clinical applications. This study presents a model merging framework to efficiently adapt general-purpose LLMs to the medical domain by countering this forgetting issue. By merging a clinical foundation model (GatorTronLlama) with a general instruct model (Llama-3.1-8B-Instruct) via interpolation-based merge methods, we seek to derive a domain-adapted model with strong performance on clinical tasks while retaining instruction-following ability. Comprehensive evaluation across medical benchmarks and five clinical generation tasks (e.g., radiology and discharge summarization) shows that merged models can effectively mitigate catastrophic forgetting, preserve clinical domain expertise, and retain instruction-following ability. In addition, our model merging strategies demonstrate training efficiency, achieving performance on par with fully fine-tuned baselines under severely constrained supervision (e.g., 64-shot vs. 256-shot). Consequently, weight-space merging constitutes a highly scalable solution for adapting open-source LLMs to clinical applications, facilitating broader deployment in resource-constrained healthcare environments.

arXiv:2604.01681v1 Announce Type: cross Abstract: Large foundation models enable powerful reasoning for autonomous systems, but mapping semantic intent to reliable real-time control remains challenging. Existing approaches either (i) let Large Language Models (LLMs) generate trajectories directly - brittle, hard to verify, and latency-prone - or (ii) adjust Model Predictive Control (MPC) objectives online - mixing slow deliberation with fast control and blurring interfaces. We propose Agentic Fast-Slow Planning, a hierarchical framework that decouples perception, reasoning, planning, and control across natural timescales. The framework contains two bridges. Perception2Decision compresses scenes into ego-centric topologies using an on-vehicle Vision-Language Model (VLM) detector, then maps them to symbolic driving directives in the cloud with an LLM decision maker - reducing bandwidth and delay while preserving interpretability. Decision2Trajectory converts directives into executable paths: Semantic-Guided A* embeds language-derived soft costs into classical search to bias solutions toward feasible trajectories, while an Agentic Refinement Module adapts planner hyperparameters using feedback and memory. Finally, MPC tracks the trajectories in real time, with optional cloud-guided references for difficult cases. Experiments in CARLA show that Agentic Fast-Slow Planning improves robustness under perturbations, reducing lateral deviation by up to 45% and completion time by over 12% compared to pure MPC and an A*-guided MPC baseline. Code is available at https://github.com/cjychenjiayi/icra2026_AFSP.