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Received — 8 April 2026 ⏭

ClawArena: Benchmarking AI Agents in Evolving Information Environments

✇cs.AI, q-bio.NC updates on arXiv.org
By: Haonian Ji · Kaiwen Xiong · Siwei Han · Peng Xia · Shi Qiu · Yiyang Zhou · Jiaqi Liu · Jinlong Li · Bingzhou Li · Zeyu Zheng · Cihang Xie · Huaxiu Yao
7 April 2026 at 12:00
arXiv:2604.04202v1 Announce Type: cross Abstract: AI agents deployed as persistent assistants must maintain correct beliefs as their information environment evolves. In practice, evidence is scattered across heterogeneous sources that often contradict one another, new information can invalidate earlier conclusions, and user preferences surface through corrections rather than explicit instructions. Existing benchmarks largely assume static, single-authority settings and do not evaluate whether agents can keep up with this complexity. We introduce ClawArena, a benchmark for evaluating AI agents in evolving information environments. Each scenario maintains a complete hidden ground truth while exposing the agent only to noisy, partial, and sometimes contradictory traces across multi-channel sessions, workspace files, and staged updates. Evaluation is organized around three coupled challenges: multi-source conflict reasoning, dynamic belief revision, and implicit personalization, whose interactions yield a 14-category question taxonomy. Two question formats, multi-choice (set-selection) and shell-based executable checks, test both reasoning and workspace grounding. The current release contains 64 scenarios across 8 professional domains, totaling 1{,}879 evaluation rounds and 365 dynamic updates. Experiments on five agent frameworks and five language models show that both model capability (15.4% range) and framework design (9.2%) substantially affect performance, that self-evolving skill frameworks can partially close model-capability gaps, and that belief revision difficulty is determined by update design strategy rather than the mere presence of updates. Code is available at https://github.com/aiming-lab/ClawArena.

Preserving Forgery Artifacts: AI-Generated Video Detection at Native Scale

✇cs.AI, q-bio.NC updates on arXiv.org
By: Zhengcen Li · Chenyang Jiang · Hang Zhao · Shiyang Zhou · Yunyang Mo · Feng Gao · Fan Yang · Qiben Shan · Shaocong Wu · Jingyong Su
7 April 2026 at 12:00
arXiv:2604.04634v1 Announce Type: cross Abstract: The rapid advancement of video generation models has enabled the creation of highly realistic synthetic media, raising significant societal concerns regarding the spread of misinformation. However, current detection methods suffer from critical limitations. They rely on preprocessing operations like fixed-resolution resizing and cropping. These operations not only discard subtle, high-frequency forgery traces but also cause spatial distortion and significant information loss. Furthermore, existing methods are often trained and evaluated on outdated datasets that fail to capture the sophistication of modern generative models. To address these challenges, we introduce a comprehensive dataset and a novel detection framework. First, we curate a large-scale dataset of over 140K videos from 15 state-of-the-art open-source and commercial generators, along with Magic Videos benchmark designed specifically for evaluating ultra-realistic synthetic content. In addition, we propose a novel detection framework built on the Qwen2.5-VL Vision Transformer, which operates natively at variable spatial resolutions and temporal durations. This native-scale approach effectively preserves the high-frequency artifacts and spatiotemporal inconsistencies typically lost during conventional preprocessing. Extensive experiments demonstrate that our method achieves superior performance across multiple benchmarks, underscoring the critical importance of native-scale processing and establishing a robust new baseline for AI-generated video detection.

TSPO: Breaking the Double Homogenization Dilemma in Multi-turn Search Policy Optimization

✇cs.AI, q-bio.NC updates on arXiv.org
By: Shichao Ma · Zhiyuan Ma · Ming Yang · Xiaofan Li · Xing Wu · Jintao Du · Yu Cheng · Weiqiang Wang · Qiliang Liu · Zhengyang Zhou · Yang Wang
7 April 2026 at 12:00
arXiv:2601.22776v2 Announce Type: replace Abstract: Multi-turn tool-integrated reasoning enables Large Language Models (LLMs) to solve complex tasks through iterative information retrieval. However, current reinforcement learning (RL) frameworks for search-augmented reasoning predominantly rely on sparse outcome-level rewards, leading to a "Double Homogenization Dilemma." This manifests as (1) Process homogenization, where the thinking, reasoning, and tooling involved in generation are ignored. (2) Intra-group homogenization, coarse-grained outcome rewards often lead to inefficiencies in intra-group advantage estimation with methods like Group Relative Policy Optimization (GRPO) during sampling. To address this, we propose Turn-level Stage-aware Policy Optimization (TSPO). TSPO introduces the First-Occurrence Latent Reward (FOLR) mechanism, allocating partial rewards to the step where the ground-truth answer first appears, thereby preserving process-level signals and increasing reward variance within groups without requiring external reward models or any annotations. Extensive experiments demonstrate that TSPO significantly outperforms state-of-the-art baselines, achieving average performance gains of 24% and 13.6% on Qwen2.5-3B and 7B models, respectively. Code is available at https://github.com/Flipped-May/TSPO.

A Data-driven Approach for Biomarker Discovery based on U-centered Distance Correlation Network: Multi-omics Warning Signals for Non-small Cell Lung Cancer

✇(Multiomics OR Omics) AND (Lung OR gastric OR Hepatocellular)
By: Xin Huang · Mei Yan · Yang Zhou
6 April 2026 at 18:00

Comb Chem High Throughput Screen. 2026 Mar 27. doi: 10.2174/0113862073445368260131002109. Online ahead of print.

ABSTRACT

INTRODUCTION/OBJECTIVE: Lung cancer is the leading cause of cancer-related mortality worldwide, and non-small cell lung cancer (NSCLC) accounts for the majority of cases. Alterations in metabolic activities play important roles in NSCLC development, wherein related genes and metabolites interact with each other, involving multiple forms.

METHODS: To comprehensively understand the pathogenic mechanisms and improve the performance of clinical early, precise diagnosis, this study proposed a data-driven approach for biomarker discovery based on U-centered distance correlation network (DCN) to investigate NSCLC metabolism-related reactions. In DCN, changes in molecular relationships during NSCLC initiation and progression are measured using the t-statistics of U-centered distance correlation for network construction, in which prospective warning signals representing NSCLC onset can be identified without human intervention. Additionally, the network construction criterion in DCN can precisely and effectively capture both linear and nonlinear molecular relationships in simple and biologically relevant manners.

RESULTS: DCN was successfully employed to analyze NSCLC metabolism-related metabolomics and genomics datasets. Statistical analyses confirmed that compared with other algorithms, the gene and metabolite biomarker panels identified by DCN provided more reliable diagnostic capabilities for clinical NSCLC detection. Biological analyses revealed that disturbed energy metabolism and lipid metabolism occurred during tumor cell proliferation and growth in NSCLC patients.

DISCUSSION: The gene ASPA and metabolite aspartic acid were significantly decreased in NSCLC samples, suggesting that the corresponding amino acid metabolic activities were intricately linked to NSCLC progression.

CONCLUSION: These findings demonstrated that DCN can further facilitate NSCLC studies to improve clinical outcomes in patients.

PMID:41937706 | DOI:10.2174/0113862073445368260131002109

A Data-driven Approach for Biomarker Discovery based on U-centered Distance Correlation Network: Multi-omics Warning Signals for Non-small Cell Lung Cancer

✇Omics In Lung
By: Xin Huang · Mei Yan · Yang Zhou
6 April 2026 at 18:00

Comb Chem High Throughput Screen. 2026 Mar 27. doi: 10.2174/0113862073445368260131002109. Online ahead of print.

ABSTRACT

INTRODUCTION/OBJECTIVE: Lung cancer is the leading cause of cancer-related mortality worldwide, and non-small cell lung cancer (NSCLC) accounts for the majority of cases. Alterations in metabolic activities play important roles in NSCLC development, wherein related genes and metabolites interact with each other, involving multiple forms.

METHODS: To comprehensively understand the pathogenic mechanisms and improve the performance of clinical early, precise diagnosis, this study proposed a data-driven approach for biomarker discovery based on U-centered distance correlation network (DCN) to investigate NSCLC metabolism-related reactions. In DCN, changes in molecular relationships during NSCLC initiation and progression are measured using the t-statistics of U-centered distance correlation for network construction, in which prospective warning signals representing NSCLC onset can be identified without human intervention. Additionally, the network construction criterion in DCN can precisely and effectively capture both linear and nonlinear molecular relationships in simple and biologically relevant manners.

RESULTS: DCN was successfully employed to analyze NSCLC metabolism-related metabolomics and genomics datasets. Statistical analyses confirmed that compared with other algorithms, the gene and metabolite biomarker panels identified by DCN provided more reliable diagnostic capabilities for clinical NSCLC detection. Biological analyses revealed that disturbed energy metabolism and lipid metabolism occurred during tumor cell proliferation and growth in NSCLC patients.

DISCUSSION: The gene ASPA and metabolite aspartic acid were significantly decreased in NSCLC samples, suggesting that the corresponding amino acid metabolic activities were intricately linked to NSCLC progression.

CONCLUSION: These findings demonstrated that DCN can further facilitate NSCLC studies to improve clinical outcomes in patients.

PMID:41937706 | DOI:10.2174/0113862073445368260131002109

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