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cs.AI, q-bio.NC updates on arXiv.org
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Benchmarking the Limits of In-Context Reinforcement Learning for Ad-Hoc Teamwork
arXiv:2605.24423v1 Announce Type: new Abstract: In-Context Reinforcement Learning (ICRL) has enabled foundation agents to adapt instantaneously to novel tasks, yet its efficacy in Ad-Hoc Teamwork (AHT)-where coordination with unknown partners is required-remains unexplored. To rigorously evaluate this, we introduce a large-scale benchmark ICRL4AHT, built upon a high-throughput JAX implementation of Overcooked-V2. Our benchmark includes a large, diverse teammate suite spanning both RL and heuris
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cs.AI, q-bio.NC updates on arXiv.org
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Claw-Anything: Benchmarking Always-On Personal Assistants with Broader Access to User's Digital World
arXiv:2605.26086v1 Announce Type: new Abstract: Large language model agents are increasingly envisioned as always-on personal assistants with access to anything relevant in the user's digital world. Yet current systems operate over only narrow slices of that world, limiting context-sensitive reasoning and effective assistance. Existing benchmarks similarly provide only partial user state and therefore fail to capture performance in such a broad, always-on setting. To address this gap, we introd
Claw-Anything: Benchmarking Always-On Personal Assistants with Broader Access to User's Digital World
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cs.AI, q-bio.NC updates on arXiv.org
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MobileGym: A Verifiable and Highly Parallel Simulation Platform for Mobile GUI Agent Research
arXiv:2605.26114v1 Announce Type: new Abstract: We present MobileGym, a browser-hosted, lightweight, fully controllable environment for everyday mobile use, targeting interaction fidelity without replicating proprietary backends. It enables two capabilities previously out of reach for everyday apps: verifiable outcome signals through deterministic state-based judging over structured JSON state, and scalable online RL through low-cost parallel rollouts. The full environment state is captured, co
MobileGym: A Verifiable and Highly Parallel Simulation Platform for Mobile GUI Agent Research
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cs.AI, q-bio.NC updates on arXiv.org
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How Should LLMs Consume High-Quality Data? Optimal Data Scheduling via Quality-Aware Functional Scaling Laws
arXiv:2605.25698v1 Announce Type: cross Abstract: High-quality data is scarce in large language model (LLM) training, yet how to schedule its use jointly with training dynamics lacks theoretical guidance. We extend functional scaling laws by incorporating a data-quality dimension, and solve the joint data-quality and batch-size scheduling problem in asymptotic closed form. The solution reveals two regimes and a dual role of high-quality data. In the noise-limited regime, high-quality data shoul
How Should LLMs Consume High-Quality Data? Optimal Data Scheduling via Quality-Aware Functional Scaling Laws
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(Multiomics OR Omics) AND (Lung OR gastric OR Hepatocellular)
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Bibliometric analysis of lung cancer organoid research: trends and emerging areas of study
J Thorac Dis. 2026 Apr 30;18(4):406. doi: 10.21037/jtd-2026-0547. Epub 2026 Apr 27.ABSTRACTBACKGROUND: Lung cancer remains the leading cause of cancer-related mortality worldwide, posing a substantial global health burden. Despite advances in early detection, molecular profiling, and targeted therapies, patient outcomes remain unsatisfactory due to tumor heterogeneity, therapeutic resistance, and the lack of reliable preclinical models. In recent years, lung cancer organoids (LCOs), patient-deri
Bibliometric analysis of lung cancer organoid research: trends and emerging areas of study
J Thorac Dis. 2026 Apr 30;18(4):406. doi: 10.21037/jtd-2026-0547. Epub 2026 Apr 27.
ABSTRACT
BACKGROUND: Lung cancer remains the leading cause of cancer-related mortality worldwide, posing a substantial global health burden. Despite advances in early detection, molecular profiling, and targeted therapies, patient outcomes remain unsatisfactory due to tumor heterogeneity, therapeutic resistance, and the lack of reliable preclinical models. In recent years, lung cancer organoids (LCOs), patient-derived three-dimensional (3D) culture systems, have demonstrated the ability to preserve the histological architecture and genomic features of primary tumors more faithfully than conventional models, making them a promising platform for translational research and precision medicine. This study aims to quantitatively evaluate the global research output, identify major contributors and collaboration patterns, and systematically uncover research hotspots and emerging trends in the field of LCOs through bibliometric analysis.
METHODS: A systematic bibliometric analysis was conducted using publications on LCOs retrieved from the Web of Science Core Collection (WoSCC). Articles published between 2015 and 2024 were included. A total of 356 publications were analyzed. Publication outputs, country and institutional contributions, collaboration networks, and keyword co-occurrence were evaluated using Bibliometrix (R package), VOSviewer, and CiteSpace.
RESULTS: The number of publications on LCOs has increased steadily over the past decade, reflecting growing research interest and technological advancement. China and the United States were identified as the leading contributors, accounting for the majority of publications, while Germany, South Korea, and Japan also demonstrated strong research capacity and active collaboration. Keyword and thematic analyses revealed several major research hotspots, including personalized medicine, drug response and resistance mechanisms, tumor microenvironment modeling, and immune-related interactions. Burst keyword analysis further identified emerging trends, such as co-culture systems, immunotherapy evaluation, and the integration of LCOs with high-throughput screening and multi-omics approaches.
CONCLUSIONS: LCOs have evolved into a versatile platform bridging basic research and clinical applications in lung cancer. This study provides a comprehensive overview of the current research landscape and highlights emerging directions in the field. Future research should focus on methodological standardization, optimization of organoid construction and evaluation, integration with multi-omics and immune models, and strengthened international collaboration to facilitate clinical translation and improve patient outcomes.
PMID:42182656 | PMC:PMC13190222 | DOI:10.21037/jtd-2026-0547
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Omics In Lung
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Bibliometric analysis of lung cancer organoid research: trends and emerging areas of study
J Thorac Dis. 2026 Apr 30;18(4):406. doi: 10.21037/jtd-2026-0547. Epub 2026 Apr 27.ABSTRACTBACKGROUND: Lung cancer remains the leading cause of cancer-related mortality worldwide, posing a substantial global health burden. Despite advances in early detection, molecular profiling, and targeted therapies, patient outcomes remain unsatisfactory due to tumor heterogeneity, therapeutic resistance, and the lack of reliable preclinical models. In recent years, lung cancer organoids (LCOs), patient-deri
Bibliometric analysis of lung cancer organoid research: trends and emerging areas of study
J Thorac Dis. 2026 Apr 30;18(4):406. doi: 10.21037/jtd-2026-0547. Epub 2026 Apr 27.
ABSTRACT
BACKGROUND: Lung cancer remains the leading cause of cancer-related mortality worldwide, posing a substantial global health burden. Despite advances in early detection, molecular profiling, and targeted therapies, patient outcomes remain unsatisfactory due to tumor heterogeneity, therapeutic resistance, and the lack of reliable preclinical models. In recent years, lung cancer organoids (LCOs), patient-derived three-dimensional (3D) culture systems, have demonstrated the ability to preserve the histological architecture and genomic features of primary tumors more faithfully than conventional models, making them a promising platform for translational research and precision medicine. This study aims to quantitatively evaluate the global research output, identify major contributors and collaboration patterns, and systematically uncover research hotspots and emerging trends in the field of LCOs through bibliometric analysis.
METHODS: A systematic bibliometric analysis was conducted using publications on LCOs retrieved from the Web of Science Core Collection (WoSCC). Articles published between 2015 and 2024 were included. A total of 356 publications were analyzed. Publication outputs, country and institutional contributions, collaboration networks, and keyword co-occurrence were evaluated using Bibliometrix (R package), VOSviewer, and CiteSpace.
RESULTS: The number of publications on LCOs has increased steadily over the past decade, reflecting growing research interest and technological advancement. China and the United States were identified as the leading contributors, accounting for the majority of publications, while Germany, South Korea, and Japan also demonstrated strong research capacity and active collaboration. Keyword and thematic analyses revealed several major research hotspots, including personalized medicine, drug response and resistance mechanisms, tumor microenvironment modeling, and immune-related interactions. Burst keyword analysis further identified emerging trends, such as co-culture systems, immunotherapy evaluation, and the integration of LCOs with high-throughput screening and multi-omics approaches.
CONCLUSIONS: LCOs have evolved into a versatile platform bridging basic research and clinical applications in lung cancer. This study provides a comprehensive overview of the current research landscape and highlights emerging directions in the field. Future research should focus on methodological standardization, optimization of organoid construction and evaluation, integration with multi-omics and immune models, and strengthened international collaboration to facilitate clinical translation and improve patient outcomes.
PMID:42182656 | PMC:PMC13190222 | DOI:10.21037/jtd-2026-0547