arXiv:2609.12422v1 Announce Type: new Abstract: Lux AI Season 3 requires agents to act under partial observability, randomized episode level dynamics, and a best of five match structure that rewards both tactical execution and fast adaptation. We present HORIZON, a hierarchical agent that combines symmetry aware spatial perception, dual memory belief tracking, relic centric graph attention, information gain driven exploration, and an opponent conditioned policy mixture. HORIZON separates short horizon control from cross match meta reasoning, while auxiliary belief and world model objectives stabilize learning. Trained with PPO in a large scale JAX simulator, the resulting agent explicitly infers hidden game parameters and opponent style. Experiments show consistent gains in match win rate, episode win rate, adaptation gain, and league rating over strong recurrent and feed forward baselines.

arXiv:2609.12746v1 Announce Type: new Abstract: Agentic pipelines for structured-query generation are rapidly expanding, but it is unclear which part of the loop produces the gain. We use LAST-CQ -- a five-agent, training-free, execution-grounded Text-to-Cypher framework -- as an instrumented testbed, running three counterfactuals over 2,471 live-database queries and six backbones spanning three vendor scale tiers. Removing correction is worth between 3.1% aggregate execution-BLEU against the single-pass system and 12.3% against a no-refinement counterfactual (up to 80.7% for the weakest backbone). Replacing schema-grounded, LLM-synthesised feedback with raw database error strings costs almost nothing (20.9% vs. 19.9% naive exact match;

arXiv:2609.12170v1 Announce Type: cross Abstract: Autonomous network management requires systems that can evaluate Network Service Intents (NSIs) under varying conditions without manual implementation of analysis logic, as envisioned in TM Forum Level~4 (L4) autonomy. Behavioral Network Digital Twins (NDTs) enable such evaluation, but existing NDTs rely on pre-defined analytical logic, limiting adaptability for evolving closed-loop control. This paper introduces the NDT factory, a multi-agent software system that synthesizes executable behavioral NDTs on demand from semantic models using Large Language Model (LLM). We validate the system using a Call Admission Control (CAC) case study, where deterministic what-if analysis serves as the admission decision process. The NDT factory generates a complete CAC NDT through parallel synthesis and orchestration, achieving 100% compilation and test pass rates across multiple runs. Simulation over 300 NSIs shows 99.3% decision agreement with a reference implementation, 90% admission rate, and correct attribution of all rejections, demonstrating reliable synthesis with deterministic, verifiable execution.

arXiv:2609.03753v3 Announce Type: replace Abstract: Cumulative culture enables humans to preserve, reuse, and extend knowledge and skills across experiences and generations. Inspired by this principle, we introduce \textit{SimSkill}, a self-evolving agent built around the Simulation of Urban MObility (SUMO) traffic simulator. SimSkill continually identifies capability gaps, generates and solves environment-grounded tasks, verifies solutions through an action--critic loop, and consolidates experience into episodic, procedural, and semantic memory. Through autonomous exploration, it builds a library of reusable skills and knowledge spanning major stages of the traffic-simulation workflow. We evaluate SimSkill on two held-out benchmarks across three backbone LLMs, with each result independently verified. It improves verified success by up to 25 percentage points, and ablations show complementary contributions from procedural and semantic memory. Its benefits remain backbone- and budget-dependent, as memory does not improve every model or uniformly reduce inference cost. More broadly, SimSkill illustrates a natural-language-centered design paradigm for LLM-based agent systems. Its high-level control logic, operating principles, and accumulated knowledge are expressed in natural language, while an LLM integrates them with executable tools and code to realize precise and reproducible execution. All code and experimental data are publicly available at https://github.com/qiliuchn/SimSkill-V1.

arXiv:2602.04850v3 Announce Type: replace-cross Abstract: Quantum chemistry is a foundational enabling tool for the fields of chemistry, materials science, computational biology and others. Despite of its power, the practical application of quantum chemistry simulations remains in the hands of qualified experts due to methodological complexity, software heterogeneity, and the need for informed interpretation of results. To bridge the accessibility gap for these tools and expand their reach to chemists with broader backgrounds, we introduce El Agente Quntur, a hierarchical, multi-agent AI system designed to operate not merely as an automation tool but as a research collaborator for computational quantum chemistry. Quntur was designed following three main strategies: i) elimination of hard-coded procedural policies in favour of reasoning-driven decisions, ii) construction of general and composable actions that facilitate generalization and efficiency, and iii) implementation of guided deep research to integrate abstract quantum-chemical reasoning across subdisciplines and a detailed understanding of the software's internal logic and syntax. Although instantiated in ORCA, these design principles are applicable to research agents more generally and easily expandable to additional quantum chemistry packages and beyond. Quntur supports the full range of calculations available in ORCA 6.0 and reasons over software documentation and scientific literature to plan, execute, adapt, and analyze in silico chemistry experiments following best practices. We discuss the advances and current bottlenecks in agentic systems operating at the research level in computational chemistry, and outline a roadmap toward a fully autonomous end-to-end computational chemistry research agent.

arXiv:2603.01131v4 Announce Type: replace-cross Abstract: Clinical diagnosis is a gradual process of evidence integration, in which physicians move from symptoms and medical history to examinations, competing hypotheses, disease relations, and treatment decisions. Large language models have advanced medical text understanding and generation. Yet their clinical use remains limited by weak evidence grounding, opaque reasoning, and inconsistent links among differential diagnosis, final diagnosis, diagnostic basis, and treatment planning. We introduce MedCollab, a multi-agent framework for full-cycle clinical diagnosis and report generation. MedCollab coordinates specialist and examination agents according to patient records. It structures agent deliberation with an Issue-Based Information System (IBIS) protocol, so that each diagnostic position is supported by patient-specific evidence and medical knowledge. It also builds Hierarchical Disease Relation Chains (HDRC) to connect accepted hypotheses through progression, complication, and comorbidity relations. During multi-round deliberation, a verifier-guided consensus module evaluates evidence support, medical plausibility, and logical conflicts. It then adjusts agent contributions and filters unsupported reasoning. Experiments on ClinicalBench and MIMIC-IV show that MedCollab outperforms leading LLMs and medical multi-agent baselines in diagnostic accuracy, evidence consistency, and clinical reasoning quality. These results indicate that structured and auditable collaboration can produce more faithful and clinically coherent diagnostic reports.

arXiv:2608.15424v2 Announce Type: replace-cross Abstract: The rapid adoption of large language models has enabled the development of clinical multi-agent systems (MAS) capable of integrating multimodal patient data and supporting increasingly complex clinical decision-making. However, the deployment of these systems in real-world healthcare settings raises critical ethical concerns related to safety, fairness, accountability, transparency, and patient trust. While numerous organizations, including the World Health Organization, the National Academy of Medicine, and the FUTURE-AI consortium, have proposed ethical frameworks and governance principles for healthcare AI, these efforts remain largely conceptual. To address this challenge, we present ETHOS (Ethics and Trust through Hierarchical Oversight System), a modular ethics framework designed as a governance meta-agent that can be integrated with any existing multi-agent system without requiring changes to its underlying architecture. ETHOS translates stakeholder-informed ethical requirements into executable runtime oversight through a layered governance approach consisting of deterministic checks, contextual reviews, and a final ethics critic. These components continuously evaluate intermediate reasoning steps and final outputs, enabling the system to identify ethical risks, request revisions, or suppress responses that fail predefined safety and trustworthiness criteria. We demonstrate ETHOS within a hepatology clinical decision-support MAS. Results show that ETHOS improves decision reliability by detecting incomplete, inconsistent, or out-of-scope evidence and appropriately increasing abstention when safe recommendations cannot be supported. By embedding ethical governance directly into system operation, ETHOS provides a practical and auditable mechanism for transforming high-level AI ethics principles into deployable safeguards.