Nature Biomedical Engineering, Published online: 05 October 2026; doi:10.1038/s41551-026-01805-5This Review highlights how organoids and organ-on-a-chip technologies are transforming gastrointestinal disease research by providing clinically relevant models of inflammation, infection and cancer and discusses future opportunities for therapeutic developments.

Nature Cancer, Published online: 22 September 2026; doi:10.1038/s43018-026-01234-yChio and colleagues describe an iron-dependent pathway with a role in the induction of cancer cachexia-linked events such as adipose browning and identify methionine sulfoxide reductase A as an important and targetable factor in this process.