Nature Biomedical Engineering, Published online: 06 October 2026; doi:10.1038/s41551-026-01786-5A nanoscale metal–organic framework (MOF)-based cancer vaccine platform enables coordinated antigen presentation and innate immune activation, resulting in tumour regression, immune memory and protection against metastasis.

npj Digital Medicine, Published online: 06 October 2026; doi:10.1038/s41746-026-03318-6SPIRIT-CONSORT-ELM: element-level annotated dataset and large language model approach for assessing randomized controlled trial reporting

Nature Cancer, Published online: 25 September 2026; doi:10.1038/s43018-026-01238-8Lee and colleagues report that ischemic stroke induces the generation of an astrocytic population that, through reduced calcium signaling, favors the recruitment of tumor-associated macrophages, thereby promoting glioma invasion in preclinical models.

Nature Cancer, Published online: 22 September 2026; doi:10.1038/s43018-026-01234-yChio and colleagues describe an iron-dependent pathway with a role in the induction of cancer cachexia-linked events such as adipose browning and identify methionine sulfoxide reductase A as an important and targetable factor in this process.