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Joint impact of pathological burden and cognitive resilience on Alzheimer’s disease risk

Nature Medicine, Published online: 11 September 2026; doi:10.1038/s41591-026-04635-9

A 15-year cohort study shows that Alzheimer’s dementia risk is jointly shaped by Alzheimer’s pathology and cognitive resilience, with high resilience linked to lower risk, even under greater pathology.
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ATP2B4 driven chromatin compaction exacerbates pancreatic cancer radiotherapy resistance

Cell Death Discovery, Published online: 25 May 2026; doi:10.1038/s41420-026-03142-7

ATP2B4 driven chromatin compaction exacerbates pancreatic cancer radiotherapy resistance
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NAT10 promotes cisplatin resistance and immune escape by increasing the expression of DUSP1 and PD-L1 in gastric cancer

Cell Death Discovery, Published online: 10 April 2026; doi:10.1038/s41420-026-03107-w

NAT10 promotes cisplatin resistance and immune escape by increasing the expression of DUSP1 and PD-L1 in gastric cancer
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Structures of Marburgvirus glycoprotein and its complex with NPC1 receptor

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10240-0

Marburgvirus glycoprotein binds to the endosomal receptor NPC1 in a distinct orientation with higher affinity compared with Ebola virus glycoprotein, accompanied by fusion-relevant rearrangements, enabling more efficient viral entry.
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