❌

Reading view

CSF clearance through arachnoid fenestrations to olfactory meningeal lymphatics

Cerebrospinal fluid (CSF) crosses arachnoid fenestrations near the olfactory bulbs to reach dural lymphatics that traverse the cribriform plate, connect to nasal lymphatics, and drain to cervical lymph nodes. Aging impairs this pathway, but intranasal VEGF-C restores the lymphatics and the CSF outflow.
  •  

Plasmin promotes hepatocellular carcinoma invasion and metastasis via CXCR4-mediated activation of PI3K/AKT/mTOR signaling

Oncogene, Published online: 09 April 2026; doi:10.1038/s41388-026-03775-z

Plasmin promotes hepatocellular carcinoma invasion and metastasis via CXCR4-mediated activation of PI3K/AKT/mTOR signaling
  •  
❌