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Fibronectin 1 mediated histone lactylation promotes malignant progression of GIST regulated by m<sup>6</sup>A modification

Cell Death Discovery, Published online: 11 September 2026; doi:10.1038/s41420-026-03338-x

Fibronectin 1 mediated histone lactylation promotes malignant progression of GIST regulated by m6A modification
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CD44v5 promotes triple-negative breast cancer cisplatin resistance by enhancing IL-4/IL-4Rα/STAT3 pathway and stabilizing membranous SLC7A11

Oncogenesis, Published online: 21 August 2026; doi:10.1038/s41389-026-00650-0

CD44v5 promotes triple-negative breast cancer cisplatin resistance by enhancing IL-4/IL-4Rα/STAT3 pathway and stabilizing membranous SLC7A11
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AI-induced never-skilling in medical education

Nature Medicine, Published online: 22 May 2026; doi:10.1038/s41591-026-04438-y

Will medical trainees who rely on AI fail to develop foundational independent clinical reasoning? This Perspective outlines a precautionary framework to preserve foundational competence while supporting safe and effective AI integration in medical training.
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Granzyme B-based CAR-T cells targeting membrane-bound HSP70 suppress solid tumor growth and metastasis

Oncogene, Published online: 18 April 2026; doi:10.1038/s41388-026-03797-7

Granzyme B-based CAR-T cells targeting membrane-bound HSP70 suppress solid tumor growth and metastasis
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FGFR1 suppresses ovarian cancer progression by modulating SIRT3-dependent lactylation and metabolic reprogramming

Cell Death Discovery, Published online: 07 April 2026; doi:10.1038/s41420-026-03054-6

FGFR1 suppresses ovarian cancer progression by modulating SIRT3-dependent lactylation and metabolic reprogramming
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