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Sequence Display enables large-scale sequence–activity datasets for rapid protein evolution

βœ‡Nature Biotechnology - Issue - nature.com science feeds
By: Linqi Cheng Β· Xinzhe Zheng Β· Shiyu Jason Jiang Β· Yu Hu Β· Yijie Liu Β· Kaiqiang Yang Β· Jinyan Rui Β· Haoxue Ding Β· Mengxi Zhang Β· Teng Yuan Β· Qianglan Lu Β· Haoxin Ye Β· Chen-Long Li Β· Yiming Guo Β· Zuotong Tian Β· Anna Qin Β· Boyang Zhou Β· Kevin K. Yang Β· Xiongyi Huang Β· Han Xiao

Nature Biotechnology, Published online: 08 April 2026; doi:10.1038/s41587-026-03087-3

Sequence Display maps protein variant activities to a sequencing-based readout.
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MAPK14/SLC7A11/GPX4 axis dysregulation drives podocyte ferroptosis via mediating glycerophospholipid metabolism

βœ‡Cell Death Discovery nature.com science feeds
By: Shi Qiu Β· Dandan Xie Β· Sifan Guo Β· Zhibo Wang Β· Ying Cai Β· Xian Wang Β· Zhencai Hu Β· Shiwei Wang Β· Chunsheng Lin Β· Hong Yao Β· Qiang Yang Β· Yu Guan Β· Qiqi Zhao Β· Songqi Tang Β· Wenjie Sun Β· Yiqiang Xie Β· Aihua Zhang

Cell Death Discovery, Published online: 11 March 2026; doi:10.1038/s41420-026-02990-7

MAPK14/SLC7A11/GPX4 axis dysregulation drives podocyte ferroptosis via mediating glycerophospholipid metabolism
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