Within the skin, glutamatergic neurons expressing neurofilament heavy chain (Nefh) play a role in aging. Loss of Nefh during aging drives skin fibroblast senescence and collagen loss, whereas glutamate supplementation improves skin aging phenotypes.

Nature, Published online: 20 May 2026; doi:10.1038/s41586-026-10571-y

The buffer pool designed to compensate for unintended carbon losses from the largest forest climate mitigation programme in the United States is too small when considering the impact of future climate change scenarios.

Cell Death Discovery, Published online: 09 March 2026; doi:10.1038/s41420-026-02950-1

Ferroptosis of smooth muscle cells in vascular diseases: from basic principles to clinical translation