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Ensuring multiomics data reproducibility for artificial intelligence with reference materials as a common calibrator

Nature Biotechnology, Published online: 01 September 2026; doi:10.1038/s41587-026-03267-1

Reference materials should be adopted as a common calibrator for multiomics measurement and co‑profiled with study samples. Multiomics results should be reported as sample‑to‑reference ratios so that they are reproducible and suitable for artificial intelligence tools.
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Electric dipole moment drives the dynamics of the TNFR1 complex I signalosome

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10304-1

Long-range interactions mediated by protein electric dipole moments have a role in driving the assembly and disassembly of super-signalling complex I for promoting NF-ΞΊB signalling.
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