Oncogene, Published online: 12 September 2026; doi:10.1038/s41388-026-03988-2

Circular RNA MCM3 recruits USP49 to stabilize PTBP1 and promote cisplatin resistance in cervical squamous cell carcinoma

Oncogene, Published online: 11 September 2026; doi:10.1038/s41388-026-03986-4

CircRHBDD1(4,5) drives malignant progression of oral squamous cell carcinoma by enhancing DKK1 mRNA stability through facilitating m⁶A-dependent IGF2BP2 binding

Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10968-9

Deep-foam photolithography uses light-controlled polymer foaming to create high-resolution, multifunctional microstructures with tunable optical, wetting and fluid-handling properties for advanced manufacturing applications.

Ancient DNA from 149 individuals at 11 sites in Gansu, China, dated to around 4,700–3,000 years ago, reveals human population history during early transcontinental exchanges of agriculture and technology, as well as contemporary social practices, at the large Mogou cemetery.

Oncogene, Published online: 29 August 2026; doi:10.1038/s41388-026-03967-7

DHCR24⁺ tumor epithelial cells drive cisplatin resistance in bladder cancer by enhancing cholesterol metabolism to activate lipid raft-associated MAPK signaling

Oncogene, Published online: 23 May 2026; doi:10.1038/s41388-026-03825-6

Lactic acid induces dendritic cell pyroptosis through MCT-1 to promote tumor immune evasion

npj Digital Medicine, Published online: 11 April 2026; doi:10.1038/s41746-026-02602-9

Graphicalized vision-language modeling for comprehensive lung nodule analysis and risk stratification

Background: Social media intervention may enhance HIV prevention among men who have sex with men, but the effect of this intervention in resource-limited settings remains unclear. Objective: This randomized controlled trial evaluated whether a social media intervention grounded in the information-motivation-behavioral skills (IMB) model could be beneficial for HIV prevention among men who have sex with men in resource-limited settings. Methods: Participants were recruited in Nanning, China, between April 2023 and April 2024. Eligible participants were randomly assigned to either the social media intervention group or the routine HIV prevention services control group. Participants in the intervention group received a 3-month social media intervention, which included completing video-based tasks. Baseline surveys were conducted, followed by follow-up surveys every 3 months, for a total of 2 follow-ups. Outcomes included HIV testing uptake, high-risk behavior, AIDS-related knowledge, safe sex self-efficacy, and attitude. Results: A total of 180 eligible men who have sex with men were enrolled (90 per group). Follow-up rates were 97.8% (88/90) and 95.5% (86/90) for the intervention and control groups, respectively. At the follow-ups, the intervention group demonstrated significantly higher uptake of HIV testing, a lower proportion of participants reporting high-risk sexual behaviors, and higher condom use self-efficacy compared to the control group (all

(Cell 188, 6283–6300.e1–e10; October 30, 2025)

The development of genetically encoded fluorescent reporters, along with their corresponding knock-in mouse lines for labeling α-Syn inclusions, enables diverse applications in studying the propagation and pathological effects of α-Syn inclusions in the live brain.

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10322-z

Combining single-cell parallel profiling of genome conformation, histone modifications, chromatin accessibility and gene expression reveals dynamics and intranuclear spatial clustering of epigenome profiles, enabling sophisticated analysis of the regulatory landscape across cell types and tissues.