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<i>TWIST1</i> mediated transcriptional activation of <i>SPON2</i> drives colorectal cancer peritoneal metastasis through stromal cell signaling network

Oncogene - Issue - nature.com science feeds

By: Zhuan Zhou · Alessandro La Ferlita · Manoj H. Palavalli · Xiongfeng Chen · Lauren Tyler · Aslam Ejaz · Joal Beane · Patricio M. Polanco · Huocong Huang · Alex C. Kim

3 April 2026 at 08:00

Oncogene, Published online: 03 April 2026; doi:10.1038/s41388-026-03743-7

TWIST1 mediated transcriptional activation of SPON2 drives colorectal cancer peritoneal metastasis through stromal cell signaling network

Genetically encoded fluorescent reporters to visualize α-synuclein pathology in live brain

Cell

By: Li Zhang · Minhui Yu · Guoqing Chen · Siyuan Ge · Mengdi Wang · Xianying Zhang · Miao Zhao · Huating Gu · Meizhu Huang · Aixue Liu · Gengxin Ran · Zeyuan Liu · Tiepeng Liao · Qi Chen · Chenjian Miao · Yao Lu · Yibing Wang · Fengchao Wang · Zhihui Liu · Hongying Zhu · Qian Wu · Zhuan Zhou · Wei Xiong · Xiaoqun Wang · Peng Cao

4 March 2026 at 08:00

The development of genetically encoded fluorescent reporters, along with their corresponding knock-in mouse lines for labeling α-Syn inclusions, enables diverse applications in studying the propagation and pathological effects of α-Syn inclusions in the live brain.