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Risk-adaptive therapy guided by dynamic ctDNA in nasopharyngeal carcinoma

βœ‡Nature - Issue - nature.com science feeds
By: Jiawei Lv Β· Dan-Xue Zheng Β· Jin-Hui Liang Β· Ning Zhang Β· Zu-Lu Ye Β· Xu-Dong Xu Β· Melvin. L. K. Chua Β· Lu-Lu Zhang Β· Zi-Ming Du Β· Zi-Chen Zhang Β· Wen-Fei Li Β· Ling-Long Tang Β· Lei Chen Β· Yan-Ping Mao Β· Rui Guo Β· Yu-Pei Chen Β· Li Lin Β· Yuan Zhang Β· Xu Liu Β· Cheng Xu Β· Zhi-Xuan Li Β· Ling-Xin Xu Β· Pan-Yang Yang Β· Kun Chen Β· Deng Bin Β· Tian-Sheng Gao Β· Jian-Ye Yan Β· Lu-Si Chen Β· Shao Hui Huang Β· Hong-Yun Zhao Β· Shu-Bin Hong Β· Yu-Sheng Jie Β· Hui-Ling Huang Β· Xu-Hua Tang Β· Jing-Ping Yun Β· Li-Zhi Liu Β· Li Tian Β· Hao-Jiang Li Β· Ji-Bin Li Β· Guan-Qun Zhou Β· Jun Ma Β· Ying Sun

Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10244-w

A clinical trial testing whether monitoring ctDNA clearance during treatment for nasopharyngeal cancer could be used to inform decisions about an individual’s subsequent therapeutic programme shows promising results.
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<i>KRAS</i>-extrachromosomal DNA drives intratumoral heterogeneity in gastric cancer

βœ‡Oncogene - Issue - nature.com science feeds
By: Rong Guan Β· Chenxi Li Β· Xinchun Dai Β· Yanyan Wang Β· Yiyuan Zhang Β· Xiao Liang Β· Shan Yu Β· Zhizhou Li Β· Kexian Dong Β· Mengdi Cai Β· Jie Wu Β· Xueyuan Jia Β· Hao Wang Β· Dapeng Hao Β· Songbin Fu Β· Wenjing Sun

Oncogene, Published online: 05 March 2026; doi:10.1038/s41388-026-03713-z

KRAS-extrachromosomal DNA drives intratumoral heterogeneity in gastric cancer
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