Cells aren’t as passive as scientists once thought—they actively create internal currents to move proteins quickly and efficiently. These “cellular winds” push materials to the front of the cell, enabling faster movement and repair. Discovered by chance and confirmed with advanced imaging, this system challenges decades of textbook biology. It may also reveal why some cancer cells spread so rapidly.

Old canned salmon turned out to be a time capsule of ocean health. Researchers found that rising levels of tiny parasitic worms in some salmon species suggest stronger, more complete marine food webs. Because these parasites depend on multiple hosts—including marine mammals—their increase may reflect ecosystem recovery over decades. What looks unappetizing may actually be a sign of a healthier ocean.

Hidden within fish DNA are powerful genetic twists that may explain one of nature’s biggest mysteries: how new species form so quickly. In Lake Malawi, hundreds of cichlid fish species evolved at lightning speed, and scientists now think “flipped” sections of DNA—called chromosomal inversions—are the secret. These inversions lock together useful gene combinations, creating “supergenes” that help fish rapidly adapt to different environments, from deep waters to sandy shores.

Scientists have finally cracked a long-standing mystery about squid and cuttlefish evolution by analyzing newly sequenced genomes alongside global datasets. The research reveals that these bizarre, intelligent creatures likely originated deep in the ocean over 100 million years ago, surviving mass extinction events by retreating into oxygen-rich deep-sea refuges. For millions of years, their evolution barely changed—until a dramatic post-extinction boom sparked rapid diversification as they moved into new shallow-water habitats.

Scientists studying Bennu samples have discovered that its chemistry is far from uniform. Organic compounds and minerals cluster into three distinct types of regions, each shaped differently by past water activity. This uneven pattern shows that water altered the asteroid in a complex, localized way. The survival of delicate organic molecules adds an important clue to how life’s building blocks may persist in space.

Scientists have transformed a groundbreaking 2D nanomaterial called MXene into an even more powerful 1D form—tiny scroll-like tubes that are incredibly thin yet highly conductive. By rolling flat sheets into hollow nanoscrolls, they’ve created structures that act like fast “highways” for ions, boosting performance in batteries, sensors, and wearable electronics.

Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03756-2

Correction: The multifunctional RNA helicase DDX39A drives glioblastoma progression by modulating WISP1 alternative splicing that induces an immunosuppressive macrophage polarization

Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03737-5

LDHA-driven lactate metabolism promotes MDSC activation and immunosuppressive microenvironment in prostate cancer

Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03754-4

Targeting FTO shows therapeutic potential in esophageal squamous cell carcinoma by modulating microRNA biogenesis

Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03740-w

X-linked cancer-associated polypeptide (XCP) from lncRNA1456 modulates PHF8 histone demethylase activity to regulate the epigenome, gene expression, and cellular pathways in breast cancer

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10446-2

Structural modifications in strain-engineered bilayer nickelate thin films

Oncogene, Published online: 01 April 2026; doi:10.1038/s41388-026-03752-6

STAT3-mediated transactivation of NOVA2 promotes lung adenocarcinoma metastasis by splicing SMAD4

Nature, Published online: 01 April 2026; doi:10.1038/d41586-026-01052-3

In-flight experiment suggests lowering soot emissions might not reduce contrail formation — plus, what can be learnt from fakery in science.

Nature, Published online: 01 April 2026; doi:10.1038/d41586-026-01001-0

Lead recycled from centuries-old ammunition provides raw materials for perovskite solar cells.

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10310-3

DNA damage burden and inadequate repair in CUX2+ cortical layer 2/3 excitatory neurons contributes to selective vulnerability in neuroinflammatory injury.

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10230-2

Dissociative ionization of H2 molecules by the combination of a phase-locked attosecond laser pair and a few-cycle NIR laser shows that ion–photoelectron entanglement influences electronic coherence in H2+, allowing control over the degree of entanglement by varying the delay between the pulses.

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10315-y

Development of the pangenome-informed genome assembly (PIGA) workflow enabled the generation of 1,116 diploid genome assemblies (55 de novo and 1,061 pangenome-informed), representing an extensive resource of medically relevant genic variations.

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10322-z

Combining single-cell parallel profiling of genome conformation, histone modifications, chromatin accessibility and gene expression reveals dynamics and intranuclear spatial clustering of epigenome profiles, enabling sophisticated analysis of the regulatory landscape across cell types and tissues.

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10313-0

Findings suggest that neural crest fate bias predominantly emerges within the neural tube, and that only a minor subset of delaminated progenitors retain multipotency to generate both sensory and sympathetic derivatives.

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10301-4

Longitudinal tracking of mice reveals that stable, specialized social roles emerge spontaneously within groups during a foraging task, with dopaminergic activity in the ventral tegmental area driving sex-divergent patterns of specialization.