Functional RNA splitting drove the evolutionary emergence of type V CRISPR-Cas systems from transposons

Cell

By: Shuai Jin · Zixu Zhu · Yunjia Li · Shouyue Zhang · Yijing Liu · Danyuan Li · Yuanqing Li · Yingfeng Luo · Zhiheng Cheng · Kevin Tianmeng Zhao · Qiang Gao · Guanglei Yang · Hongchao Li · Ronghong Liang · Rui Zhang · Jin-Long Qiu · Yong E. Zhang · Jun-Jie Gogo Liu · Caixia Gao

17 March 2026 at 08:00

(Cell 188, 6283–6300.e1–e10; October 30, 2025)

Restoring circadian rhythms in the hypothalamic paraventricular nucleus reverses aging biomarkers and extends lifespan in male mice

Cell

By: Haijiao Zhao · Meimei Liao · Ran Huo · Ting He · Hongni Tian · Zeqi Li · Chen Chen · Ziqing Yu · Juan Chai · Xiaocui Song · Ruichao Shao · Shuhua Ying · Wen Gao · Ling Liu · Di Sang · Qi Li · Haohong Li · Fengchao Wang · Dapeng Ju · Eric Erquan Zhang

4 March 2026 at 08:00

Enhancing circadian amplitude in mouse hypothalamic paraventricular nucleus neurons by 3′-deoxyadenosine treatment alleviates age-related pathologies and extends lifespan.

Structure of the mouse cytoplasmic lattice

Nature - Issue - nature.com science feeds

By: Pengliang Chi · Xiang Wang · Jialu Li · Jingrui Huang · Sicheng Ju · Sibei Liu · Li Yan · Yuechao Lu · Zihan Zhang · Zhuo Han · Jinhong Li · Qianqian Qi · Qingting Liu · Yiren Zeng · Li Guo · Xiaofeng Zhang · Long Gui · Dong Deng

31 March 2026 at 08:00

Nature, Published online: 31 March 2026; doi:10.1038/s41586-026-10442-6

Structure of the mouse cytoplasmic lattice

CSF1R T567M mutation induces microglial dysfunction and synaptic impairment in patient iPSC-derived cerebral organoids of CSF1R-related disorder

Cell Death Discovery nature.com science feeds

By: Li Chi · Haitao Tu · Zhihong Li · Lifeng Qiu · Zhi-Wei Zhang · Sook-Yoong Chia · Jayne Yi Tan · Ivy A. W. Ho · Yuin-Han Loh · Eng-King Tan · Wei Teng · Zhong Pei · Zbigniew K. Wszolek · Adeline S. L. Ng · Li Zeng

12 March 2026 at 08:00

Cell Death Discovery, Published online: 12 March 2026; doi:10.1038/s41420-026-02995-2

CSF1R T567M mutation induces microglial dysfunction and synaptic impairment in patient iPSC-derived cerebral organoids of CSF1R-related disorder

Dexamethasone promotes neutrophil ROS-mediated tumor killing through the glucocorticoid receptor

Oncogene - Issue - nature.com science feeds

By: Zhanhong Liu · Rongrong Sun · Yinghong Li · Ziqi Zhang · Peiqing Huang · Yipeng Zhou · Pengbo Hou · Wenqing Mu · Gerry Melino · Peishan Li · Yufang Shi · Changshun Shao

6 March 2026 at 08:00

Oncogene, Published online: 06 March 2026; doi:10.1038/s41388-026-03708-w

Dexamethasone promotes neutrophil ROS-mediated tumor killing through the glucocorticoid receptor

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