Clinical application of base editing for treating β-thalassaemia

Nature - Issue - nature.com science feeds

By: Yongrong Lai · Rongrong Liu · Lijie Wang · Xu-Kai Ma · Yaliang Li · Gaohui Yang · Lingling Shi · Yi-Lin Guo · Zhenbin Wei · Xuemei Zhou · Wenchao Xu · Yaofeng Hou · Annarita Miccio · Bei Yang · Xiaodun Mou · Li Yang · Jia Chen

8 April 2026 at 08:00

Nature, Published online: 08 April 2026; doi:10.1038/s41586-026-10342-9

A clinical phase 1 trial of a single infusion of CS-101, CD34+ cells modified using a transformer base editor to reactivate fetal haemoglobin production, led to early and enduring transfusion independence in patients with β-thalassaemia.

Integrating large language models for enhanced predictive analytics in healthcare

npj Digital Medicine

By: Yuli Wang · Yuwei Dai · Robin Wang · Tej Mehta · Premal Trivedi · Thao Vu · Cheng Ting Lin · Li Yang · Zhicheng Jiao · Ihab Kamel · Jing Wu · Harrison Bai

2 April 2026 at 08:00

npj Digital Medicine, Published online: 02 April 2026; doi:10.1038/s41746-026-02572-y

Integrating large language models for enhanced predictive analytics in healthcare

Structure of the mouse cytoplasmic lattice

Nature - Issue - nature.com science feeds

By: Pengliang Chi · Xiang Wang · Jialu Li · Jingrui Huang · Sicheng Ju · Sibei Liu · Li Yan · Yuechao Lu · Zihan Zhang · Zhuo Han · Jinhong Li · Qianqian Qi · Qingting Liu · Yiren Zeng · Li Guo · Xiaofeng Zhang · Long Gui · Dong Deng

31 March 2026 at 08:00

Nature, Published online: 31 March 2026; doi:10.1038/s41586-026-10442-6

Structure of the mouse cytoplasmic lattice

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